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4,4'-(2-(4-methylpiperidyl)-1-hydroxyethyl)biphenyl and choline

4,4'-(2-(4-methylpiperidyl)-1-hydroxyethyl)biphenyl has been researched along with choline in 5 studies

*Choline: A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. [MeSH]

*Choline: A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. [MeSH]

Compound Research Comparison

Studies
(4,4'-(2-(4-methylpiperidyl)-1-hydroxyethyl)biphenyl)
Trials
(4,4'-(2-(4-methylpiperidyl)-1-hydroxyethyl)biphenyl)
Recent Studies (post-2010)
(4,4'-(2-(4-methylpiperidyl)-1-hydroxyethyl)biphenyl)
Studies
(choline)
Trials
(choline)
Recent Studies (post-2010) (choline)
70019,6286084,345

Protein Interaction Comparison

ProteinTaxonomy4,4'-(2-(4-methylpiperidyl)-1-hydroxyethyl)biphenyl (IC50)choline (IC50)
Sodium- and chloride-dependent creatine transporter 1Rattus norvegicus (Norway rat)1.6
High affinity choline transporter 1Mus musculus (house mouse)1.6

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Long, JP; Sheff, KY; Yorek, MA3
Bhatnagar, RK; Cannon, JG; Flynn, JR; Long, JP; Tedford, CE1
Cannon, JG; Flynn, JR; Long, JP; Sheff, KY; Tedford, CE; Yorek, MA1

Other Studies

5 other study(ies) available for 4,4'-(2-(4-methylpiperidyl)-1-hydroxyethyl)biphenyl and choline

ArticleYear
Hemicholinium-3 derivatives A-4 and A-5 alter choline metabolism in NB41A3 neuroblastoma cells.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:1

    Topics: Animals; Biphenyl Compounds; Choline; Ethanolamine; Ethanolamines; Mice; Neuroblastoma; Phosphatidylcholines; Phospholipids; Piperidines; S-Adenosylmethionine; Tumor Cells, Cultured

1991
Hemicholinium-3 derivatives A-4 and A-5 affect choline and acetylcholine metabolism.
    European journal of pharmacology, 1991, Feb-25, Volume: 206, Issue:2

    Topics: Acetylcholine; Animals; Biological Transport, Active; Biphenyl Compounds; Choline; Hemicholinium 3; Neurons; Parasympatholytics; Piperidines; Tumor Cells, Cultured

1991
Characterization of the effect of two 4-methyl piperidine derivatives of hemicholinium-3, A-4 and A-5, on choline transport.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:1

    Topics: Animals; Biological Transport; Biphenyl Compounds; Choline; Dose-Response Relationship, Drug; Mice; Neuroblastoma; Parasympatholytics; Piperidines; Sodium; Tumor Cells, Cultured

1990
Alterations in acetylcholine metabolism in rat striatal slices by a 4-methyl piperidine analog of hemicholinium-3.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:2

    Topics: Acetylcholine; Animals; Biphenyl Compounds; Choline; Chromatography, High Pressure Liquid; Corpus Striatum; Hemicholinium 3; Piperidines; Potassium; Rats; Structure-Activity Relationship

1988
Stereoisomers of quaternary and tertiary 4-methyl piperidine analogs of hemicholinium-3.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:2

    Topics: Acetylcholine; Animals; Biphenyl Compounds; Caudate Nucleus; Cells, Cultured; Choline; Hemicholinium 3; Male; Piperidines; Rabbits; Rats; Rats, Inbred Strains; Sciatic Nerve; Stereoisomerism

1988