Page last updated: 2024-09-03

4'-phosphopantetheine and cysteine

4'-phosphopantetheine has been researched along with cysteine in 14 studies

Compound Research Comparison

Studies
(4'-phosphopantetheine)
Trials
(4'-phosphopantetheine)
Recent Studies (post-2010)
(4'-phosphopantetheine)
Studies
(cysteine)
Trials
(cysteine)
Recent Studies (post-2010) (cysteine)
12902940,13241811,457

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's3 (21.43)18.2507
2000's8 (57.14)29.6817
2010's1 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Knudsen, J; Mikkelsen, J; Smith, S; Stern, A1
Katiyar, SS; Pan, D; Porter, JW1
Flint, DH1
Joshi, AK; Smith, S; Witkowski, A1
Falick, AM; Joshi, AK; Rangan, VS; Smith, S; Witkowska, HE; Witkowski, A1
Blaesse, M; Jung, G; Kupke, T; Schmid, D; Steinbacher, S; Uebele, M1
Suo, Z; Tseng, CC; Walsh, CT1
Culianez-Macia, FA; Hernandez-Acosta, P; Kupke, T; Steinbacher, S1
Begley, TP; Strauss, E1
Culiáñez-Macià, FA; Hernández-Acosta, P; Kupke, T1
Amara, AA; Rehm, BH1
Begley, TP; Brand, LA; McLafferty, FW; Strauss, E; Zhai, H1
Bodner, MJ; Freeman, MF; Li, R; Moshos, KA; Townsend, CA1
Abe, T; Kawamura, S; Kobayashi, K; Kobayashi, M; Sakaguchi, T; Shiiba, K1

Other Studies

14 other study(ies) available for 4'-phosphopantetheine and cysteine

ArticleYear
Stoichiometry of substrate binding to rat liver fatty acid synthetase.
    The Biochemical journal, 1985, Sep-01, Volume: 230, Issue:2

    Topics: Acetates; Acetic Acid; Acetyl Coenzyme A; Animals; Binding Sites; Cysteamine; Cysteine; Fatty Acid Synthases; Iodoacetamide; Liver; Malonates; Malonyl Coenzyme A; Pantetheine; Rats

1985
Role of cysteine and 4'-phosphopantetheine in the inactivation of pigeon liver fatty acid synthetase by S-(4-bromo-2,3-dioxobutyl)-coenzyme A.
    Biochemical and biophysical research communications, 1982, Jan-29, Volume: 104, Issue:2

    Topics: Affinity Labels; Animals; Binding Sites; Coenzyme A; Columbidae; Cysteine; Fatty Acid Synthases; Kinetics; Liver; Organophosphorus Compounds; Pantetheine; Protein Binding; Sulfhydryl Compounds

1982
Escherichia coli contains a protein that is homologous in function and N-terminal sequence to the protein encoded by the nifS gene of Azotobacter vinelandii and that can participate in the synthesis of the Fe-S cluster of dihydroxy-acid dehydratase.
    The Journal of biological chemistry, 1996, Jul-05, Volume: 271, Issue:27

    Topics: Alanine; Amino Acid Sequence; Azotobacter vinelandii; Bacterial Proteins; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Disulfides; Escherichia coli; Genes, Bacterial; Haemophilus influenzae; Hydro-Lyases; Iron-Sulfur Proteins; Kinetics; Macromolecular Substances; Molecular Sequence Data; Naphthalenesulfonates; Pantetheine; Peptide Fragments; Pyridoxal Phosphate; Sequence Homology, Amino Acid; Sulfhydryl Reagents

1996
Characterization of the interthiol acyltransferase reaction catalyzed by the beta-ketoacyl synthase domain of the animal fatty acid synthase.
    Biochemistry, 1997, Dec-23, Volume: 36, Issue:51

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acyl Carrier Protein; Acyl Coenzyme A; Acyltransferases; Animals; Binding Sites; Cysteine; Escherichia coli; Fatty Acid Synthases; Fatty Acids; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Pantetheine; Rats; Recombinant Proteins; Substrate Specificity; Sulfhydryl Compounds

1997
Dibromopropanone cross-linking of the phosphopantetheine and active-site cysteine thiols of the animal fatty acid synthase can occur both inter- and intrasubunit. Reevaluation of the side-by-side, antiparallel subunit model.
    The Journal of biological chemistry, 1999, Apr-23, Volume: 274, Issue:17

    Topics: Acetone; Animals; Binding Sites; Chromatography, Gel; Cysteine; Electrophoresis, Polyacrylamide Gel; Evaluation Studies as Topic; Fatty Acid Synthases; Hydrogen-Ion Concentration; Models, Chemical; Molecular Weight; Pantetheine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfhydryl Compounds

1999
Molecular characterization of lantibiotic-synthesizing enzyme EpiD reveals a function for bacterial Dfp proteins in coenzyme A biosynthesis.
    The Journal of biological chemistry, 2000, Oct-13, Volume: 275, Issue:41

    Topics: Amino Acid Motifs; Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Binding Sites; Carboxy-Lyases; Chromatography, Gel; Coenzyme A; Cysteine; Escherichia coli; Flavin Mononucleotide; Flavoproteins; Molecular Sequence Data; Mutation; Oxidoreductases; Pantetheine; Pantothenic Acid; Peptides; Protein Binding; Protein Conformation; Recombinant Fusion Proteins; Sequence Homology, Amino Acid

2000
Purification, priming, and catalytic acylation of carrier protein domains in the polyketide synthase and nonribosomal peptidyl synthetase modules of the HMWP1 subunit of yersiniabactin synthetase.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Jan-02, Volume: 98, Issue:1

    Topics: Acyl Carrier Protein; Acylation; Acyltransferases; Apoproteins; Bacillus subtilis; Bacterial Outer Membrane Proteins; Bacterial Proteins; Cloning, Molecular; Cysteine; Escherichia coli; Holoenzymes; Iron-Binding Proteins; Kinetics; Malonyl Coenzyme A; Molecular Structure; Molecular Weight; Multienzyme Complexes; Pantetheine; Peptide Fragments; Peptide Synthases; Periplasmic Binding Proteins; Phenols; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein Subunits; Recombinant Proteins; Siderophores; Thiazoles; Yersinia pestis

2001
Arabidopsis thaliana flavoprotein AtHAL3a catalyzes the decarboxylation of 4'-Phosphopantothenoylcysteine to 4'-phosphopantetheine, a key step in coenzyme A biosynthesis.
    The Journal of biological chemistry, 2001, Jun-01, Volume: 276, Issue:22

    Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Binding Sites; Carboxy-Lyases; Catalysis; Chromatography, Gel; Coenzyme A; Crystallography, X-Ray; Cysteine; Electrophoresis, Polyacrylamide Gel; Immunoblotting; Models, Chemical; Models, Molecular; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Mutation; Oxidoreductases; Pantetheine; Pantothenic Acid; Peptide Synthases; Plant Proteins; Polymerase Chain Reaction; Protein Binding; Protein Conformation; Salts; Sequence Homology, Amino Acid; Signal Transduction; Time Factors

2001
Mechanistic studies on phosphopantothenoylcysteine decarboxylase.
    Journal of the American Chemical Society, 2001, Jul-04, Volume: 123, Issue:26

    Topics: Carboxy-Lyases; Catalysis; Coenzyme A; Cysteine; Cytidine Monophosphate; Cytidine Triphosphate; Enzyme Activation; Escherichia coli; Molecular Structure; Pantetheine; Pantothenic Acid; Peptide Synthases; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity

2001
4'-phosphopantetheine and coenzyme A biosynthesis in plants.
    The Journal of biological chemistry, 2003, Oct-03, Volume: 278, Issue:40

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Arabidopsis; Biochemical Phenomena; Biochemistry; Cell Line; Cloning, Molecular; Coenzyme A; Cysteine; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Genome, Plant; Magnesium; Models, Chemical; Molecular Sequence Data; Nucleotidyltransferases; Osmosis; Pantetheine; Plants; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Time Factors

2003
Replacement of the catalytic nucleophile cysteine-296 by serine in class II polyhydroxyalkanoate synthase from Pseudomonas aeruginosa-mediated synthesis of a new polyester: identification of catalytic residues.
    The Biochemical journal, 2003, Sep-01, Volume: 374, Issue:Pt 2

    Topics: Acyltransferases; Amino Acid Sequence; Amino Acid Substitution; Animals; Catalytic Domain; Cysteine; Epoxide Hydrolases; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Pantetheine; Polyesters; Protein Folding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Pseudomonas aeruginosa; Sequence Alignment; Serine; Substrate Specificity

2003
Mechanistic studies on phosphopantothenoylcysteine decarboxylase: trapping of an enethiolate intermediate with a mechanism-based inactivating agent.
    Biochemistry, 2004, Dec-14, Volume: 43, Issue:49

    Topics: Binding Sites; Carboxy-Lyases; Catalysis; Cysteine; Decarboxylation; Enzyme Inhibitors; Enzyme Stability; Flavin Mononucleotide; Humans; Kinetics; Mutagenesis, Site-Directed; Pantetheine; Pantothenic Acid; Serine; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Sulfhydryl Compounds

2004
Four enzymes define the incorporation of coenzyme A in thienamycin biosynthesis.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Aug-12, Volume: 105, Issue:32

    Topics: Bacterial Proteins; Coenzyme A; Cysteamine; Cysteine; Genes, Bacterial; Multigene Family; Pantetheine; Streptomyces; Thienamycins

2008
Dipeptide synthesis by internal adenylation domains of a multidomain enzyme involved in nonribosomal peptide synthesis.
    The Journal of general and applied microbiology, 2019, Mar-08, Volume: 65, Issue:1

    Topics: Adenosine Monophosphate; Coenzyme A Ligases; Cysteine; Dipeptides; Escherichia coli; Multienzyme Complexes; Oligopeptides; Pantetheine; Peptide Synthases; Protein Domains; Recombinant Proteins; Substrate Specificity

2019