4'-phosphopantetheine has been researched along with coenzyme a in 35 studies
| Studies (4'-phosphopantetheine) | Trials (4'-phosphopantetheine) | Recent Studies (post-2010) (4'-phosphopantetheine) | Studies (coenzyme a) | Trials (coenzyme a) | Recent Studies (post-2010) (coenzyme a) |
|---|---|---|---|---|---|
| 129 | 0 | 29 | 5,653 | 12 | 718 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (25.71) | 18.7374 |
| 1990's | 2 (5.71) | 18.2507 |
| 2000's | 11 (31.43) | 29.6817 |
| 2010's | 11 (31.43) | 24.3611 |
| 2020's | 2 (5.71) | 2.80 |
| Authors | Studies |
|---|---|
| Cebe, M; Perahia, D | 1 |
| Neely, JR; Tahiliani, AG | 1 |
| Gurinovich, VA; Moiseenok, AG; Sheibak, VM | 1 |
| Burton, DN; Yu, HL | 1 |
| Jackowski, S; Rock, CO | 2 |
| Gross, CJ; Henderson, LM; Shibata, K | 1 |
| Katiyar, SS; Pan, D; Porter, JW | 1 |
| Drueckhammer, DG; Gehring, AM; Lambalot, RH; Vogel, KW; Walsh, CT | 1 |
| Bucovaz, ET; Macleod, RM; Morrison, JC; Whybrew, WD | 1 |
| Kleinkauf, H | 1 |
| Blaesse, M; Jung, G; Kupke, T; Schmid, D; Steinbacher, S; Uebele, M | 1 |
| Bugg, CW; Huang, F; Yarus, M | 1 |
| Culianez-Macia, FA; Hernandez-Acosta, P; Kupke, T; Steinbacher, S | 1 |
| Begley, TP; Strauss, E | 1 |
| Bhattacharjee, JK; Evans, SA; Guo, S; Wilkes, MB | 1 |
| Dunaway-Mariano, D; Luo, L; Taylor, KL; Wei, Y; Xiang, H; Zhang, W | 1 |
| Culiáñez-Macià, FA; Hernández-Acosta, P; Kupke, T | 1 |
| ALBERTS, AW; MAJERUS, PW; VAGELOS, PR | 1 |
| Case, H; de Dreu, P; Miller, JR; Mueller, WT; Ohren, J; Sarver, RW; Thanabal, V | 1 |
| Bodner, MJ; Freeman, MF; Li, R; Moshos, KA; Townsend, CA | 1 |
| Doyle, S; Frizzell, A; Stack, D; Tomkins, K | 1 |
| Bhagawati, M; Brunk, A; Paterok, D; Piehler, J; Podoplelova, Y; Reichel, A; Waichman, S | 1 |
| Mesecar, AD; Wubben, TJ | 1 |
| Borgaro, JG; Chang, A; Machutta, CA; Tonge, PJ; Zhang, X | 1 |
| Chang, SY; Chen, T; Cheng, CS; Jia, KF; Lin, MS; Yin, HS | 1 |
| Bettencourt, C; Chiapparini, L; Demchenko, N; Dusi, S; Garavaglia, B; Goffrini, P; Gout, I; Gregory, A; Haack, TB; Hamada, J; Hayflick, S; Houlden, H; Invernizzi, F; Kurian, MA; Nardocci, N; Pasqualato, S; Prokisch, H; Sanford, L; Schwarzmayr, T; Strom, TM; Tigano, M; Tiranti, V; Tsuchiya, Y; Valletta, L; Venco, P; Wieland, T; Zorzi, G | 1 |
| Atomi, H; Imanaka, T; Ishibashi, T; Kishimoto, A; Kita, A; Miki, K; Tomita, H; Yokooji, Y | 1 |
| Cao, R; Chen, C; Li, P; Maurmann, L; Zhang, W | 1 |
| Baratashvili, M; Colombelli, C; Grzeschik, NA; Hayflick, S; Kanon, B; Kosec, G; Lambrechts, RA; Nollen, EA; Petković, H; Podgoršek, A; Reijngoud, DJ; Schaap, O; Sibon, OC; Srinivasan, B; Tiranti, V; van der Zwaag, M | 1 |
| Sibon, OC; Strauss, E | 1 |
| Basak, A; Biswas, R; Das, AK; Das, PK; Dutta, D; Maiti, MK; Singh, BK | 1 |
| Cobb, J; Duffy, M; Fox, R; Freed, A; Gray, N; Gregory, AM; Hamada, J; Hayflick, SJ; Hogarth, P; Jeong, SY; Jin, H; Lambrechts, R; Nilsen, A; Pham, T; Placzek, A; Rai, P; Ralle, M; Schwanemann, L; Sibon, OC; van der Zwaag, M; Wakeman, K; Woltjer, RL; Zhen, D | 1 |
| Chen, N; Wang, C | 1 |
| Dhembla, C; Kundu, S; Sundd, M; Yadav, U | 1 |
1 review(s) available for 4'-phosphopantetheine and coenzyme a
| Article | Year |
|---|---|
Chemical Labeling of Protein 4'-Phosphopantetheinylation.
Topics: Coenzyme A; Models, Molecular; Molecular Structure; Pantetheine; Protein Processing, Post-Translational | 2021 |
34 other study(ies) available for 4'-phosphopantetheine and coenzyme a
| Article | Year |
|---|---|
Molecular orbital studies on the conformation of the phosphopantetheine moiety of coenzyme A.
Topics: Coenzyme A; Hydrogen Bonding; Molecular Conformation; Organophosphorus Compounds; Pantetheine; Quantum Theory; Sulfhydryl Compounds | 1977 |
Mitochondrial synthesis of coenzyme A is on the external surface.
Topics: Adenosine Triphosphate; Animals; Atractyloside; Coenzyme A; Dinitrophenols; In Vitro Techniques; Mitochondria, Heart; Pantetheine; Rats; Uncoupling Agents | 1987 |
Hepatic CoA, S-acyl-CoA, biosynthetic precursors of the coenzyme and pantothenate-protein complexes in dietary pantothenic acid deficiency.
Topics: Acyl Coenzyme A; Animals; Body Weight; Coenzyme A; Liver; Male; Pantetheine; Pantothenic Acid; Proteins; Rats | 1987 |
Adaptive synthesis of rat liver fatty acid synthetase: evidence for in vitro formation of active enzyme from inactive protein precursors and 4'-phosphopantetheine.
Topics: Animals; Carbon Radioisotopes; Coenzyme A; Dietary Fats; Enzyme Activation; Fatty Acid Synthases; Liver; Male; Organophosphorus Compounds; Pantetheine; Pantothenic Acid; Rats; Starvation; Sulfhydryl Compounds | 1974 |
Metabolism of 4'-phosphopantetheine in Escherichia coli.
Topics: Acyl Carrier Protein; Alanine; Coenzyme A; Escherichia coli; Pantetheine; Pantothenic Acid; Sulfhydryl Compounds | 1984 |
Hydrolysis and absorption of pantothenate and its coenzymes in the rat small intestine.
Topics: Absorption; Animals; Carbon Radioisotopes; Coenzyme A; Coenzymes; Hydrolysis; Intestine, Small; Male; Pantetheine; Pantothenic Acid; Rats; Rats, Inbred Strains | 1983 |
Regulation of coenzyme A biosynthesis.
Topics: Acyl Carrier Protein; beta-Alanine; Coenzyme A; Escherichia coli; Organophosphorus Compounds; Pantetheine; Pantothenic Acid | 1981 |
Role of cysteine and 4'-phosphopantetheine in the inactivation of pigeon liver fatty acid synthetase by S-(4-bromo-2,3-dioxobutyl)-coenzyme A.
Topics: Affinity Labels; Animals; Binding Sites; Coenzyme A; Columbidae; Cysteine; Fatty Acid Synthases; Kinetics; Liver; Organophosphorus Compounds; Pantetheine; Protein Binding; Sulfhydryl Compounds | 1982 |
Ability of Streptomyces spp. acyl carrier proteins and coenzyme A analogs to serve as substrates in vitro for E. coli holo-ACP synthase.
Topics: Acyl Carrier Protein; Anti-Bacterial Agents; Cloning, Molecular; Coenzyme A; DNA Primers; Escherichia coli; Molecular Structure; Multienzyme Complexes; Pantetheine; Polymerase Chain Reaction; Recombinant Proteins; Streptomyces; Substrate Specificity; Transferases (Other Substituted Phosphate Groups) | 1997 |
The coenzyme A-synthesizing protein complex and its proposed role in CoA biosynthesis in bakers' yeast.
Topics: Catalysis; Coenzyme A; Feedback; Fungal Proteins; Molecular Weight; Multienzyme Complexes; Pantetheine; Peptide Synthases; Protein Binding; Saccharomyces cerevisiae | 1997 |
The role of 4'-phosphopantetheine in t' biosynthesis of fatty acids, polyketides and peptides.
Topics: Carrier Proteins; Coenzyme A; Fatty Acids; Pantetheine; Peptides | 2000 |
Molecular characterization of lantibiotic-synthesizing enzyme EpiD reveals a function for bacterial Dfp proteins in coenzyme A biosynthesis.
Topics: Amino Acid Motifs; Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Binding Sites; Carboxy-Lyases; Chromatography, Gel; Coenzyme A; Cysteine; Escherichia coli; Flavin Mononucleotide; Flavoproteins; Molecular Sequence Data; Mutation; Oxidoreductases; Pantetheine; Pantothenic Acid; Peptides; Protein Binding; Protein Conformation; Recombinant Fusion Proteins; Sequence Homology, Amino Acid | 2000 |
RNA-Catalyzed CoA, NAD, and FAD synthesis from phosphopantetheine, NMN, and FMN.
Topics: Coenzyme A; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Gene Library; NAD; Nicotinamide Mononucleotide; Pantetheine; RNA; Sequence Analysis, RNA | 2000 |
Arabidopsis thaliana flavoprotein AtHAL3a catalyzes the decarboxylation of 4'-Phosphopantothenoylcysteine to 4'-phosphopantetheine, a key step in coenzyme A biosynthesis.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Binding Sites; Carboxy-Lyases; Catalysis; Chromatography, Gel; Coenzyme A; Crystallography, X-Ray; Cysteine; Electrophoresis, Polyacrylamide Gel; Immunoblotting; Models, Chemical; Models, Molecular; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Mutation; Oxidoreductases; Pantetheine; Pantothenic Acid; Peptide Synthases; Plant Proteins; Polymerase Chain Reaction; Protein Binding; Protein Conformation; Salts; Sequence Homology, Amino Acid; Signal Transduction; Time Factors | 2001 |
Mechanistic studies on phosphopantothenoylcysteine decarboxylase.
Topics: Carboxy-Lyases; Catalysis; Coenzyme A; Cysteine; Cytidine Monophosphate; Cytidine Triphosphate; Enzyme Activation; Escherichia coli; Molecular Structure; Pantetheine; Pantothenic Acid; Peptide Synthases; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity | 2001 |
Novel posttranslational activation of the LYS2-encoded alpha-aminoadipate reductase for biosynthesis of lysine and site-directed mutational analysis of conserved amino acid residues in the activation domain of Candida albicans.
Topics: Aldehyde Oxidoreductases; Amino Acid Sequence; Apoenzymes; Candida albicans; Coenzyme A; Conserved Sequence; Enzyme Activation; Holoenzymes; L-Aminoadipate-Semialdehyde Dehydrogenase; Lysine; Pantetheine; Protein Processing, Post-Translational | 2001 |
Role of active site binding interactions in 4-chlorobenzoyl-coenzyme A dehalogenase catalysis.
Topics: Acyl Coenzyme A; Binding Sites; Binding, Competitive; Catalysis; Coenzyme A; Enzyme Stability; Hydrolases; Kinetics; Ligands; Mutagenesis, Site-Directed; Pantetheine; Substrate Specificity; Thermodynamics | 2001 |
4'-phosphopantetheine and coenzyme A biosynthesis in plants.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Arabidopsis; Biochemical Phenomena; Biochemistry; Cell Line; Cloning, Molecular; Coenzyme A; Cysteine; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Genome, Plant; Magnesium; Models, Chemical; Molecular Sequence Data; Nucleotidyltransferases; Osmosis; Pantetheine; Plants; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Time Factors | 2003 |
ACYL CARRIER PROTEIN. IV. THE IDENTIFICATION OF 4'-PHOSPHOPANTETHEINE AS THE PROSTHETIC GROUP OF THE ACYL CARRIER PROTEIN.
Topics: Acyl Carrier Protein; Alkaline Phosphatase; Amines; Carbon Isotopes; Chemistry Techniques, Analytical; Chromatography; Coenzyme A; Electrophoresis; Lactobacillus; Lactones; Metabolism; Pantetheine; Pantothenic Acid; Pepsin A; Peptide Hydrolases; Phosphates; Protein Hydrolysates; Proteins; Radiometry; Research | 1965 |
Phosphopantetheine adenylyltransferase from Escherichia coli: investigation of the kinetic mechanism and role in regulation of coenzyme A biosynthesis.
Topics: Calorimetry; Coenzyme A; Escherichia coli; Kinetics; Models, Molecular; Nucleotidyltransferases; Pantetheine; Protein Binding; Protein Conformation | 2007 |
Four enzymes define the incorporation of coenzyme A in thienamycin biosynthesis.
Topics: Bacterial Proteins; Coenzyme A; Cysteamine; Cysteine; Genes, Bacterial; Multigene Family; Pantetheine; Streptomyces; Thienamycins | 2008 |
Solid phase 4'-phosphopantetheinylation: fungal thiolation domains are targets for chemoenzymatic modification.
Topics: Aspergillus fumigatus; Bacterial Proteins; Biocatalysis; Coenzyme A; Pantetheine; Recombinant Proteins; Transferases (Other Substituted Phosphate Groups) | 2009 |
Functional immobilization and patterning of proteins by an enzymatic transfer reaction.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Coenzyme A; Glass; Immobilized Proteins; Interferon-alpha; Models, Molecular; Oligopeptides; Pantetheine; Polyethylene Glycols; Protein Structure, Tertiary; Receptor, Interferon alpha-beta; Spectrum Analysis; Substrate Specificity; Surface Properties; Transferases (Other Substituted Phosphate Groups) | 2010 |
Kinetic, thermodynamic, and structural insight into the mechanism of phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis.
Topics: Adenosine Triphosphate; Calorimetry; Coenzyme A; Crystallography, X-Ray; Feedback, Physiological; Kinetics; Models, Biological; Models, Molecular; Mycobacterium tuberculosis; Nucleotidyltransferases; Pantetheine; Protein Conformation; Protein Structure, Quaternary; Recombinant Proteins; Thermodynamics | 2010 |
Substrate recognition by β-ketoacyl-ACP synthases.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Acetyltransferases; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Coenzyme A; Escherichia coli; Escherichia coli Proteins; Fatty Acid Synthase, Type II; Kinetics; Molecular Sequence Data; Mutation; Mycobacterium tuberculosis; Palmitoyl Coenzyme A; Pantetheine; Phosphotransferases (Alcohol Group Acceptor); Substrate Specificity | 2011 |
Experimentally validated novel inhibitors of Helicobacter pylori phosphopantetheine adenylyltransferase discovered by virtual high-throughput screening.
Topics: Adenosine Triphosphate; Anti-Bacterial Agents; Bacterial Proteins; Binding Sites; Coenzyme A; Databases, Chemical; Drug Discovery; Enzyme Inhibitors; Helicobacter pylori; High-Throughput Screening Assays; Methotrexate; Microbial Sensitivity Tests; Molecular Docking Simulation; Nucleotidyltransferases; Pantetheine; Protein Binding | 2013 |
Exome sequence reveals mutations in CoA synthase as a cause of neurodegeneration with brain iron accumulation.
Topics: Brain; Cloning, Molecular; Coenzyme A; Escherichia coli; Exome; Female; Fibroblasts; Gene Expression Regulation; Humans; Iron; Male; Mitochondria; Mutation, Missense; Nerve Degeneration; Pantetheine; Pedigree; Phosphorylation; Saccharomyces cerevisiae; Transferases | 2014 |
Crystal structure of phosphopantothenate synthetase from Thermococcus kodakarensis.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Archaeal Proteins; Binding Sites; Coenzyme A; Crystallography, X-Ray; Multiprotein Complexes; Pantetheine; Peptide Synthases; Sequence Alignment; Thermococcus | 2014 |
Inhibitors of polyhydroxyalkanoate (PHA) synthases: synthesis, molecular docking, and implications.
Topics: Acyltransferases; Aldehydes; Animals; Bacterial Proteins; Biocatalysis; Biodegradation, Environmental; Coenzyme A; Cupriavidus necator; Dogs; Enzyme Assays; Enzyme Inhibitors; Esterases; Kinetics; Lipase; Molecular Docking Simulation; Pantetheine; Polyhydroxyalkanoates; Structural Homology, Protein; Substrate Specificity; Sulfolobus solfataricus | 2015 |
Extracellular 4'-phosphopantetheine is a source for intracellular coenzyme A synthesis.
Topics: Animals; Caenorhabditis elegans; Cell Line; Coenzyme A; Coenzyme A Ligases; Drosophila; Female; HEK293 Cells; Humans; Longevity; Male; Mice, Inbred C57BL; Pantetheine; Phosphotransferases (Alcohol Group Acceptor) | 2015 |
Coenzyme A: to make it or uptake it?
Topics: Animals; Biological Transport; Biosynthetic Pathways; Cell Membrane Permeability; Coenzyme A; Humans; Pantetheine | 2016 |
Decrypting the oscillating nature of the 4'-phosphopantetheine arm in acyl carrier protein AcpM of Mycobacterium tuberculosis.
Topics: Amino Acid Motifs; Azoles; Bacterial Proteins; Binding Sites; Carrier Proteins; Cloning, Molecular; Coenzyme A; Escherichia coli; Fluorescent Dyes; Gene Expression; Genetic Vectors; Molecular Docking Simulation; Molecular Dynamics Simulation; Mycobacterium tuberculosis; Mycolic Acids; Nitrobenzenes; Pantetheine; Protein Binding; Protein Conformation, alpha-Helical; Protein Interaction Domains and Motifs; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity | 2019 |
4'-Phosphopantetheine corrects CoA, iron, and dopamine metabolic defects in mammalian models of PKAN.
Topics: Animals; Biomarkers; Coenzyme A; Dopamine; Genotype; Iron; Mice; Pantetheine; Pantothenate Kinase-Associated Neurodegeneration; Phosphotransferases (Alcohol Group Acceptor) | 2019 |
Lipoate protein ligase B primarily recognizes the C
Topics: Acyl Carrier Protein; Acyltransferases; Coenzyme A; Escherichia coli; Escherichia coli Proteins; Ligases; Pantetheine; Thioctic Acid | 2022 |