Page last updated: 2024-09-03

4'-hydroxydiclofenac and warfarin

4'-hydroxydiclofenac has been researched along with warfarin in 2 studies

Compound Research Comparison

Studies
(4'-hydroxydiclofenac)
Trials
(4'-hydroxydiclofenac)
Recent Studies (post-2010)
(4'-hydroxydiclofenac)
Studies
(warfarin)
Trials
(warfarin)
Recent Studies (post-2010) (warfarin)
4302536,5732,14314,728

Protein Interaction Comparison

ProteinTaxonomy4'-hydroxydiclofenac (IC50)warfarin (IC50)
Vitamin K epoxide reductase complex subunit 1 Homo sapiens (human)0.0088

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bencsik, T; Boda, G; Kroon, PA; Lemli, B; Needs, PW; Poór, M1
Bedwell, DW; Hall, SD; Mohutsky, MA; Rougée, LRA; Ruterbories, KJ1

Other Studies

2 other study(ies) available for 4'-hydroxydiclofenac and warfarin

ArticleYear
Interaction of quercetin and its metabolites with warfarin: Displacement of warfarin from serum albumin and inhibition of CYP2C9 enzyme.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 88

    Topics: Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2C9 Inhibitors; Diclofenac; Drug Interactions; Flavonoids; Humans; Metabolome; Quercetin; Serum Albumin; Spectrometry, Fluorescence; Ultrafiltration; Warfarin

2017
The Impact of the Hepatocyte-to-Plasma pH Gradient on the Prediction of Hepatic Clearance and Drug-Drug Interactions for CYP2C9 and CYP3A4 Substrates.
    Drug metabolism and disposition: the biological fate of chemicals, 2017, Volume: 45, Issue:9

    Topics: Computer Simulation; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dextromethorphan; Diclofenac; Drug Interactions; Female; Hepatocytes; Humans; Hydrogen-Ion Concentration; Kinetics; Male; Midazolam; Plasma; Testosterone; Warfarin

2017