4'-hydroxydiclofenac has been researched along with tolbutamide in 3 studies
Studies (4'-hydroxydiclofenac) | Trials (4'-hydroxydiclofenac) | Recent Studies (post-2010) (4'-hydroxydiclofenac) | Studies (tolbutamide) | Trials (tolbutamide) | Recent Studies (post-2010) (tolbutamide) |
---|---|---|---|---|---|
43 | 0 | 25 | 5,368 | 238 | 265 |
Protein | Taxonomy | 4'-hydroxydiclofenac (IC50) | tolbutamide (IC50) |
---|---|---|---|
Cytochrome P450 2C9 | Homo sapiens (human) | 0.392 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (66.67) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Huang, HH; Lin, LH; Zhang, P; Zhong, DF | 1 |
Dostalek, M; Hanesova, M; Jurica, J; Linhart, I; Pistovcakova, J; Sulcova, A; Tomandl, J | 1 |
Di Nardo, G; Gilardi, G; Goyal, A; Sideri, A; Tsotsou, GE | 1 |
3 other study(ies) available for 4'-hydroxydiclofenac and tolbutamide
Article | Year |
---|---|
[The inhibition of CYP2C9 isoenzyme in Cunninghamella blakesleeana AS 3. 910].
Topics: Aryl Hydrocarbon Hydroxylases; Benzbromarone; Biotransformation; Catalysis; Chromatography, High Pressure Liquid; Cunninghamella; Cytochrome P-450 CYP2C9; Diclofenac; Dose-Response Relationship, Drug; Drug Interactions; Fungal Proteins; Indomethacin; Isoenzymes; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Sulfaphenazole; Tolbutamide; Valproic Acid | 2006 |
Effect of methamphetamine on cytochrome P450 activity.
Topics: Animals; Central Nervous System Stimulants; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dextromethorphan; Diclofenac; Excitatory Amino Acid Antagonists; Hypnotics and Sedatives; Hypoglycemic Agents; In Vitro Techniques; Kinetics; Liver; Male; Methamphetamine; Midazolam; Perfusion; Rats; Rats, Wistar; Steroid 21-Hydroxylase; Tolbutamide | 2007 |
Identification of mutant Asp251Gly/Gln307His of cytochrome P450 BM3 for the generation of metabolites of diclofenac, ibuprofen and tolbutamide.
Topics: Asparagine; Bacillus megaterium; Catalysis; Cytochrome P-450 Enzyme System; Diclofenac; Drug Discovery; Escherichia coli; Glutamine; Glycine; Histidine; Humans; Hydroxylation; Ibuprofen; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Tolbutamide | 2012 |