Compounds > 4'-hydroxydiclofenac
Page last updated: 2024-09-03

4'-hydroxydiclofenac and acetaminophen

4'-hydroxydiclofenac has been researched along with acetaminophen in 3 studies

Compound Research Comparison

Studies
(4'-hydroxydiclofenac)		Trials
(4'-hydroxydiclofenac)		Recent Studies (post-2010)
(4'-hydroxydiclofenac)		Studies
(acetaminophen)		Trials
(acetaminophen)		Recent Studies (post-2010) (acetaminophen)
4302520,6962,8488,242

Protein Interaction Comparison

ProteinTaxonomy4'-hydroxydiclofenac (IC50)acetaminophen (IC50)
MyoglobinHomo sapiens (human)2.3

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hanna, I; Homann, MJ; Vail, RB; Zaks, A1
Bateman, KP; Gaudreault, M; Hughes, CS; Letarte, S; Lévesque, JF; Nicoll-Griffith, DA; Picard, P; Wu, J1
Klopčič, I; Markovič, T; Mlinarič-Raščan, I; Sollner Dolenc, M1

Other Studies

3 other study(ies) available for 4'-hydroxydiclofenac and acetaminophen

ArticleYear
Preparative synthesis of drug metabolites using human cytochrome P450s 3A4, 2C9 and 1A2 with NADPH-P450 reductase expressed in Escherichia coli.
    Journal of industrial microbiology & biotechnology, 2005, Volume: 32, Issue:2

    Topics: Acetaminophen; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cloning, Molecular; Culture Media; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diclofenac; Escherichia coli; Fermentation; Glycerol; Hydroxytestosterones; NADPH-Ferrihemoprotein Reductase; Oxygen; Pharmaceutical Preparations; Phenacetin; Recombinant Proteins; Temperature; Testosterone

2005
High-throughput cytochrome P450 inhibition assays using laser diode thermal desorption-atmospheric pressure chemical ionization-tandem mass spectrometry.
    Analytical chemistry, 2007, Jun-15, Volume: 79, Issue:12

    Topics: Acetaminophen; Atmospheric Pressure; Binding, Competitive; Biological Assay; Chromatography, Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextrorphan; Diclofenac; Enzyme Inhibitors; Hydroxytestosterones; Lasers; Protein Isoforms; Reproducibility of Results; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors

2007
Endocrine disrupting activities and immunomodulatory effects in lymphoblastoid cell lines of diclofenac, 4-hydroxydiclofenac and paracetamol.
    Toxicology letters, 2018, Sep-15, Volume: 294

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Androgen Receptor Antagonists; Androgens; Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Cell Line; Cell Survival; Cells, Cultured; Cytokines; Diclofenac; Endocrine Disruptors; Estrogens; Genes, Reporter; Humans; Immunologic Factors; Lymphocytes; Receptors, Androgen; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Thyroid Hormone; Recombinant Fusion Proteins; Structure-Activity Relationship

2018