Compounds > 4'-deoxydoxorubicinol
Page last updated: 2024-09-03

4'-deoxydoxorubicinol and epirubicin

4'-deoxydoxorubicinol has been researched along with epirubicin in 5 studies

Compound Research Comparison

Studies
(4'-deoxydoxorubicinol)		Trials
(4'-deoxydoxorubicinol)		Recent Studies (post-2010)
(4'-deoxydoxorubicinol)		Studies
(epirubicin)		Trials
(epirubicin)		Recent Studies (post-2010) (epirubicin)
7205,4531,8381,570

Protein Interaction Comparison

ProteinTaxonomy4'-deoxydoxorubicinol (IC50)epirubicin (IC50)
Genome polyprotein 0.75
Tyrosine-protein kinase FynHomo sapiens (human)5.181

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dobbs, NA; Twelves, CJ1
Bastholt, L; Dalmark, M; Gjedde, SB; Jakobsen, P; Mouridsen, HT; Nielsen, OS; Petersen, D; Pfeiffer, P; Rose, C; Sandberg, E1
Baldini, E; Bocci, G; Conte, PF; Danesi, R; Del Tacca, M; Di Paolo, A; Fogli, S; Gennari, A; Innocenti, F; Salvadori, B1
de Vries, EG; Dodde, WI; Groen, HJ; Hendriks, G; Maring, JG; Uges, DR; Wachters, FM1
Gianni, L; Menna, P; Minotti, G; Salvatorelli, E1

Trials

2 trial(s) available for 4'-deoxydoxorubicinol and epirubicin

ArticleYear
A randomized study of epirubicin at four different dose levels in advanced breast cancer. Feasibility of myelotoxicity prediction through single blood-sample measurement.
    Cancer chemotherapy and pharmacology, 1991, Volume: 28, Issue:6

    Topics: Bone Marrow; Breast Neoplasms; Dose-Response Relationship, Drug; Doxorubicin; Epirubicin; Female; Humans; Infusions, Intravenous; Leukocyte Count; Prognosis; Regression Analysis; Time Factors

1991
Pharmacokinetics and pharmacodynamics of combination chemotherapy with paclitaxel and epirubicin in breast cancer patients.
    British journal of clinical pharmacology, 2002, Volume: 53, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Doxorubicin; Drug Administration Schedule; Drug Interactions; Epirubicin; Female; Glycerol; Humans; In Vitro Techniques; Infusions, Intravenous; Middle Aged; Paclitaxel

2002

Other Studies

3 other study(ies) available for 4'-deoxydoxorubicinol and epirubicin

ArticleYear
Measurement of epidoxorubicin and its metabolites by high-performance liquid chromatography using an advanced automated sample processor.
    Journal of chromatography, 1991, Dec-06, Volume: 572, Issue:1-2

    Topics: Chromatography, High Pressure Liquid; Doxorubicin; Epirubicin; Glucuronates; Humans; Reproducibility of Results; Spectrometry, Fluorescence

1991
Determination of epirubicin and its metabolite epirubicinol in saliva and plasma by HPLC.
    Therapeutic drug monitoring, 2003, Volume: 25, Issue:4

    Topics: Antibiotics, Antineoplastic; Calibration; Chromatography, High Pressure Liquid; Doxorubicin; Epirubicin; Humans; Linear Models; Saliva; Sensitivity and Specificity; Spectrometry, Fluorescence

2003
Defective taxane stimulation of epirubicinol formation in the human heart: insight into the cardiac tolerability of epirubicin-taxane chemotherapies.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:2

    Topics: Aged; Antineoplastic Agents; Cytosol; Docetaxel; Doxorubicin; Epirubicin; Female; Fluorenes; Heart; Humans; Hydantoins; Hydrogen Peroxide; Male; Middle Aged; Myocardium; Paclitaxel; Reactive Oxygen Species; Taxoids

2007