Compounds > 4'-deoxy-4'-iododoxorubicin
Page last updated: 2024-09-02

4'-deoxy-4'-iododoxorubicin and daunorubicin

4'-deoxy-4'-iododoxorubicin has been researched along with daunorubicin in 8 studies

Compound Research Comparison

Studies
(4'-deoxy-4'-iododoxorubicin)		Trials
(4'-deoxy-4'-iododoxorubicin)		Recent Studies (post-2010)
(4'-deoxy-4'-iododoxorubicin)		Studies
(daunorubicin)		Trials
(daunorubicin)		Recent Studies (post-2010) (daunorubicin)
671308,2398861,310

Protein Interaction Comparison

ProteinTaxonomy4'-deoxy-4'-iododoxorubicin (IC50)daunorubicin (IC50)
72 kDa type IV collagenaseHomo sapiens (human)1.9
Multidrug resistance-associated protein 1 Homo sapiens (human)8
Histone deacetylase 1Homo sapiens (human)0.047
Histone deacetylase 8Homo sapiens (human)0.22
Histone deacetylase 6Homo sapiens (human)0.02

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's5 (62.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beck, WT; Danks, MK; Friche, E1
Franchi, F; Giannarelli, D; Konovalova, N; Seminara, P1
Andreoni, A; Colasanti, A; Malatesta, V; Roberti, G1
Hamm, K; Hossfeld, DK; Mayer, U; Mross, K1
Robert, J; Schott, B1
Kaye, SB; Kerr, AM; Kerr, DJ; Wheldon, TE1
Capranico, G; Dasdia, T; Riva, A; Tinelli, S; Zunino, F1
Baccarani, M; Damiani, D; Lauria, F; Michelutti, A; Michieli, M; Pipan, C; Raspadori, D1

Other Studies

8 other study(ies) available for 4'-deoxy-4'-iododoxorubicin and daunorubicin

ArticleYear
Characterization of tumor cell resistance to 4'-deoxy-4'-iododoxorubicin developed in Ehrlich ascites cells in vivo.
    Cancer research, 1992, Oct-15, Volume: 52, Issue:20

    Topics: Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Carcinoma, Ehrlich Tumor; Cell Line; Daunorubicin; Dihydropyridines; DNA Topoisomerases, Type II; DNA-Binding Proteins; Doxorubicin; Drug Resistance; Macromolecular Substances; Membrane Glycoproteins; Mice; Neoplasm Proteins; Teniposide; Tumor Cells, Cultured

1992
Fractional incorporation of radionucleotides, a marker of in vitro tumor cell chemosensitivity in colorectal cancer.
    Oncology, 1991, Volume: 48, Issue:6

    Topics: Antineoplastic Agents; Colorectal Neoplasms; Daunorubicin; DNA, Neoplasm; Doxorubicin; Humans; In Vitro Techniques; Liver Neoplasms; Mitomycin; RNA, Neoplasm; Thymidine; Tritium; Tumor Cells, Cultured; Uridine

1991
Photocytotoxicity of anthracyclines upon laser excitation in their long-wavelength absorption bands.
    Radiation research, 1991, Volume: 127, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Daunorubicin; Doxorubicin; In Vitro Techniques; Photochemotherapy; Rats; Rats, Inbred F344

1991
High-performance liquid chromatography of iodo-doxorubicin and fluorescent metabolites in plasma samples.
    Journal of chromatography, 1990, Aug-24, Volume: 530, Issue:1

    Topics: Antibiotics, Antineoplastic; Chromatography, High Pressure Liquid; Daunorubicin; Doxorubicin; Humans; Molecular Structure

1990
Comparative activity of anthracycline 13-dihydrometabolites against rat glioblastoma cells in culture.
    Biochemical pharmacology, 1989, Nov-15, Volume: 38, Issue:22

    Topics: Animals; Antibiotics, Antineoplastic; Cell Division; Daunorubicin; DNA, Neoplasm; Doxorubicin; Drug Resistance; Epirubicin; Glioma; Rats; Tumor Cells, Cultured

1989
In vitro chemosensitivity testing using the multicellular tumor spheroid model.
    Cancer drug delivery, 1987, Volume: 4, Issue:2

    Topics: Antibiotics, Antineoplastic; Cell Survival; Daunorubicin; Doxorubicin; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Microscopy, Fluorescence; Tumor Cells, Cultured

1987
Markedly reduced levels of anthracycline-induced DNA strand breaks in resistant P388 leukemia cells and isolated nuclei.
    Cancer research, 1987, Jul-15, Volume: 47, Issue:14

    Topics: Animals; Antibiotics, Antineoplastic; Cell Line; Cell Nucleus; Daunorubicin; DNA; Doxorubicin; Idarubicin; Leukemia P388; Leukemia, Experimental; Mice; Naphthacenes; Nucleic Acid Conformation

1987
A comparative analysis of the sensitivity of multidrug resistant (MDR) and non-MDR cells to different anthracycline derivatives.
    Leukemia & lymphoma, 1993, Volume: 9, Issue:3

    Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Colonic Neoplasms; Daunorubicin; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Gene Expression; Humans; Idarubicin; Leukemia-Lymphoma, Adult T-Cell; Membrane Glycoproteins; Tumor Cells, Cultured

1993