4'-demethylpodophyllotoxin has been researched along with etoposide in 5 studies
| Studies (4'-demethylpodophyllotoxin) | Trials (4'-demethylpodophyllotoxin) | Recent Studies (post-2010) (4'-demethylpodophyllotoxin) | Studies (etoposide) | Trials (etoposide) | Recent Studies (post-2010) (etoposide) |
|---|---|---|---|---|---|
| 8 | 0 | 1 | 18,306 | 3,693 | 4,900 |
| Protein | Taxonomy | 4'-demethylpodophyllotoxin (IC50) | etoposide (IC50) |
|---|---|---|---|
| nuclear receptor coactivator 1 isoform 1 [Homo sapiens] | Homo sapiens (human) | 1.153 | |
| nuclear receptor coactivator 3 isoform a | Homo sapiens (human) | 1.4284 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 3.187 | |
| Caspase-3 | Homo sapiens (human) | 1 | |
| DNA topoisomerase 2-beta | Homo sapiens (human) | 0.4299 | |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 4.18 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, HX; Cheng, YC; Guo, X; Lee, KH; Shen, YC; Wang, ZQ; Zhang, YL | 1 |
| Feringa, BL; Jansen, JF; Kellogg, RM; Konings, AW; Middel, O; Pras, N; van Oeveren, A; van Uden, W; Woerdenbag, HJ | 1 |
| Cheng, YC; Cho, SJ; Lee, KH; Suffness, M; Tropsha, A | 1 |
| Charlton, JL | 1 |
| Chen, H; Hua, HM; Li, ZL; Liu, XQ; Sun, YJ; Zhou, W | 1 |
1 review(s) available for 4'-demethylpodophyllotoxin and etoposide
| Article | Year |
|---|---|
Antiviral activity of lignans.
Topics: Animals; Antiviral Agents; Humans; Lignans; Plants, Medicinal; Viruses | 1998 |
4 other study(ies) available for 4'-demethylpodophyllotoxin and etoposide
| Article | Year |
|---|---|
Antitumor agents, 130, Novel 4 beta-arylamino derivatives of 3',4'-didemethoxy-3',4'-dioxo-4-deoxypodophyllotoxin as potent inhibitors of human DNA topoisomerase II.
Topics: Antineoplastic Agents, Phytogenic; DNA; DNA Damage; DNA, Neoplasm; Humans; KB Cells; Podophyllotoxin; Topoisomerase II Inhibitors | 1992 |
Synthesis and cytotoxicity of novel lignans.
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Humans; Lignans; Lung Neoplasms; Tumor Cells, Cultured | 1995 |
Antitumor agents. 163. Three-dimensional quantitative structure-activity relationship study of 4'-O-demethylepipodophyllotoxin analogs using the modified CoMFA/q2-GRS approach.
Topics: Antineoplastic Agents; Computer Graphics; DNA; DNA Topoisomerases, Type I; Models, Molecular; Molecular Conformation; Molecular Structure; Nucleic Acid Conformation; Podophyllotoxin; Structure-Activity Relationship | 1996 |
Three new cytotoxic aryltetralin lignans from Sinopodophyllum emodi.
Topics: Antineoplastic Agents, Phytogenic; Berberidaceae; Cell Line, Tumor; Cell Survival; Glucosides; HeLa Cells; Humans; Inhibitory Concentration 50; Lignans; Magnetic Resonance Spectroscopy; Plant Roots; Podophyllotoxin | 2011 |