Page last updated: 2024-09-03

4'-demethylepipodophyllotoxin and gl 331

4'-demethylepipodophyllotoxin has been researched along with gl 331 in 3 studies

Compound Research Comparison

Studies
(4'-demethylepipodophyllotoxin)
Trials
(4'-demethylepipodophyllotoxin)
Recent Studies (post-2010)
(4'-demethylepipodophyllotoxin)
Studies
(gl 331)
Trials
(gl 331)
Recent Studies (post-2010) (gl 331)
390182814

Protein Interaction Comparison

ProteinTaxonomy4'-demethylepipodophyllotoxin (IC50)gl 331 (IC50)
Hypoxia-inducible factor 1-alphaHomo sapiens (human)0.001

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, HX; Cheng, YC; Guo, X; Lee, KH; Shen, YC; Wang, ZQ; Zhang, YL1
Cheng, YC; Cho, SJ; Lee, KH; Suffness, M; Tropsha, A1
Feng, J; Golbraikh, A; Lee, KH; Tropsha, A; Xiao, YD; Xiao, Z1

Other Studies

3 other study(ies) available for 4'-demethylepipodophyllotoxin and gl 331

ArticleYear
Antitumor agents, 130, Novel 4 beta-arylamino derivatives of 3',4'-didemethoxy-3',4'-dioxo-4-deoxypodophyllotoxin as potent inhibitors of human DNA topoisomerase II.
    Journal of natural products, 1992, Volume: 55, Issue:8

    Topics: Antineoplastic Agents, Phytogenic; DNA; DNA Damage; DNA, Neoplasm; Humans; KB Cells; Podophyllotoxin; Topoisomerase II Inhibitors

1992
Antitumor agents. 163. Three-dimensional quantitative structure-activity relationship study of 4'-O-demethylepipodophyllotoxin analogs using the modified CoMFA/q2-GRS approach.
    Journal of medicinal chemistry, 1996, Mar-29, Volume: 39, Issue:7

    Topics: Antineoplastic Agents; Computer Graphics; DNA; DNA Topoisomerases, Type I; Models, Molecular; Molecular Conformation; Molecular Structure; Nucleic Acid Conformation; Podophyllotoxin; Structure-Activity Relationship

1996
Antitumor agents. 213. Modeling of epipodophyllotoxin derivatives using variable selection k nearest neighbor QSAR method.
    Journal of medicinal chemistry, 2002, May-23, Volume: 45, Issue:11

    Topics: Antineoplastic Agents; Models, Molecular; Podophyllotoxin; Quantitative Structure-Activity Relationship

2002