Page last updated: 2024-09-03

4'-demethylepipodophyllotoxin and fluorouracil

4'-demethylepipodophyllotoxin has been researched along with fluorouracil in 2 studies

Compound Research Comparison

Studies
(4'-demethylepipodophyllotoxin)
Trials
(4'-demethylepipodophyllotoxin)
Recent Studies (post-2010)
(4'-demethylepipodophyllotoxin)
Studies
(fluorouracil)
Trials
(fluorouracil)
Recent Studies (post-2010) (fluorouracil)
3901845,5629,30714,663

Protein Interaction Comparison

ProteinTaxonomy4'-demethylepipodophyllotoxin (IC50)fluorouracil (IC50)
Epidermal growth factor receptorHomo sapiens (human)0.32
Thymidylate synthaseMus musculus (house mouse)1.58
AromataseHomo sapiens (human)0.63

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, SW; Tian, X; Tu, YQ1
Jing, YX; Qi, SN; Shi, RY; Wang, LS; Yang, YJ; Yao, J; Yuan, HQ1

Other Studies

2 other study(ies) available for 4'-demethylepipodophyllotoxin and fluorouracil

ArticleYear
Synthesis and cytotoxic activity of novel derivatives of 4'-demethylepipodophyllotoxin.
    Bioorganic & medicinal chemistry letters, 2004, Oct-18, Volume: 14, Issue:20

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Etoposide; Fluorouracil; Humans; Podophyllotoxin; Structure-Activity Relationship

2004
Induction of apoptotic DNA fragmentation mediated by mitochondrial pathway with caspase-3-dependent BID cleavage in human gastric cancer cells by a new nitroxyl spin-labeled derivative of podophyllotoxin.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 90

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Caspase 9; Cell Line, Tumor; Cytochromes c; DNA Fragmentation; Etoposide; Fluorouracil; Humans; Mitochondria; Podophyllotoxin; Spin Labels; Stomach Neoplasms

2017