4'-demethyldesoxypodophyllotoxin has been researched along with podophyllotoxin in 8 studies
| Studies (4'-demethyldesoxypodophyllotoxin) | Trials (4'-demethyldesoxypodophyllotoxin) | Recent Studies (post-2010) (4'-demethyldesoxypodophyllotoxin) | Studies (podophyllotoxin) | Trials (podophyllotoxin) | Recent Studies (post-2010) (podophyllotoxin) |
|---|---|---|---|---|---|
| 16 | 0 | 6 | 3,119 | 226 | 782 |
| Protein | Taxonomy | 4'-demethyldesoxypodophyllotoxin (IC50) | podophyllotoxin (IC50) |
|---|---|---|---|
| nuclear receptor subfamily 0 group B member 1 | Homo sapiens (human) | 2.145 | |
| Tubulin alpha-1A chain | Sus scrofa (pig) | 0.6733 | |
| Tubulin beta chain | Sus scrofa (pig) | 0.622 | |
| Glucocorticoid receptor | Homo sapiens (human) | 0.014 | |
| Tubulin beta-4A chain | Homo sapiens (human) | 1.7233 | |
| Tubulin beta chain | Homo sapiens (human) | 1.7233 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.6 | |
| Tubulin alpha-3C chain | Homo sapiens (human) | 1.7233 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 4 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 5 | |
| Tubulin alpha-1B chain | Homo sapiens (human) | 1.7233 | |
| Tubulin alpha-4A chain | Homo sapiens (human) | 1.7233 | |
| Tubulin beta-4B chain | Homo sapiens (human) | 1.7233 | |
| Tubulin beta-3 chain | Homo sapiens (human) | 1.7233 | |
| Tubulin beta-2A chain | Homo sapiens (human) | 1.7233 | |
| Tubulin beta-8 chain | Homo sapiens (human) | 1.7233 | |
| Calcium-activated potassium channel subunit alpha-1 | Rattus norvegicus (Norway rat) | 0.56 | |
| Tubulin beta-2B chain | Bos taurus (cattle) | 0.8685 | |
| Tubulin alpha-3E chain | Homo sapiens (human) | 1.7233 | |
| Tubulin alpha-1A chain | Homo sapiens (human) | 1.7233 | |
| Similar to alpha-tubulin isoform 1 | Bos taurus (cattle) | 0.907 | |
| Similar to alpha-tubulin isoform 1 | Bos taurus (cattle) | 0.7744 | |
| Tubulin alpha-1C chain | Homo sapiens (human) | 1.7233 | |
| Tubulin beta-6 chain | Homo sapiens (human) | 1.7233 | |
| Tubulin beta-2B chain | Homo sapiens (human) | 1.7233 | |
| Tubulin beta-1 chain | Homo sapiens (human) | 1.7233 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chai, H; Cruz, JG; Hernández, L; Mar, W; Novelo, M; Pereda-Miranda, R; Pezzuto, JM | 1 |
| Castro, MA; Faircloth, GT; Gordaliza, M; López-Vázquez, ML; Miguel del Corral, JM; San Feliciano, A | 1 |
| But, PP; Hon, PM; Jiang, RW; Li, LL; Li, SL; Shaw, PC; Xu, HX; Ye, WC; Zhou, JR; Zhou, Y | 1 |
| Chen, H; Hua, HM; Li, ZL; Liu, XQ; Sun, YJ; Zhou, W | 1 |
| Chen, SW; Ding, YL; Huang, WT; Hui, L; Liu, J; Liu, JF | 1 |
| Bunyapraphatsara, N; Fong, HH; Jutiviboonsuk, A; Ma, C; Manh Cuong, N; Soejarto, DD; Tan, GT; Van Hung, N; Zhang, H | 1 |
| Lv, M; Sun, H; Tian, X; Wang, J; Xu, H; Yao, X; Zhang, X | 1 |
| Chen, SW; Gao, YY; Huang, WT; Hui, L; Jin, Y; Jin, YX; Liu, J; Zhou, NN | 1 |
8 other study(ies) available for 4'-demethyldesoxypodophyllotoxin and podophyllotoxin
| Article | Year |
|---|---|
Cytotoxic constituents from Hyptis verticillata.
Topics: Animals; Antineoplastic Agents, Phytogenic; Artemia; Candida albicans; Drug Screening Assays, Antitumor; Humans; Leukemia P388; Mexico; Mice; Microbial Sensitivity Tests; Plants, Medicinal; Podophyllotoxin; Rats | 1993 |
Immunosuppressive cyclolignans.
Topics: Animals; Cells, Cultured; Immunosuppressive Agents; Lignans; Lymphocyte Culture Test, Mixed; Mice; Mice, Inbred BALB C; Molecular Structure; Spleen; Structure-Activity Relationship; T-Lymphocytes | 1996 |
Lignans from Dysosma versipellis with inhibitory effects on prostate cancer cell lines.
Topics: Antineoplastic Agents, Phytogenic; Berberidaceae; Drug Screening Assays, Antitumor; Humans; Lignans; Male; Molecular Structure; Plant Roots; Plants, Medicinal; Podophyllotoxin; Prostatic Neoplasms; Rhizome; Tumor Cells, Cultured | 2007 |
Three new cytotoxic aryltetralin lignans from Sinopodophyllum emodi.
Topics: Antineoplastic Agents, Phytogenic; Berberidaceae; Cell Line, Tumor; Cell Survival; Glucosides; HeLa Cells; Humans; Inhibitory Concentration 50; Lignans; Magnetic Resonance Spectroscopy; Plant Roots; Podophyllotoxin | 2011 |
Synthesis and biological evaluation of conjugates of deoxypodophyllotoxin and 5-FU as inducer of caspase-3 and -7.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 7; Cell Line, Tumor; Drugs, Chinese Herbal; Enzyme Activation; Fluorouracil; G2 Phase Cell Cycle Checkpoints; Humans; M Phase Cell Cycle Checkpoints; Neoplasms; Podophyllotoxin | 2012 |
Bioactive constituents from roots of Bursera tonkinensis.
Topics: Antineoplastic Agents, Phytogenic; Bursera; Drug Screening Assays, Antitumor; Humans; Lignans; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Plant Roots; Podophyllotoxin; Tumor Cells, Cultured | 2005 |
Semisynthesis and quantitative structure-activity relationship (QSAR) study of novel aromatic esters of 4'-demethyl-4-deoxypodophyllotoxin as insecticidal agents.
Topics: Animals; Benzene; Esters; Insecticides; Larva; Moths; Podophyllotoxin; Quantitative Structure-Activity Relationship | 2009 |
Carbamates of 4'-demethyl-4-deoxypodophyllotoxin: synthesis, cytotoxicity and cell cycle effects.
Topics: Antineoplastic Agents; Carbamates; Cell Cycle; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; G2 Phase Cell Cycle Checkpoints; Humans; Hydrophobic and Hydrophilic Interactions; M Phase Cell Cycle Checkpoints; Podophyllotoxin | 2011 |