Page last updated: 2024-09-04

4'-demethyldesoxypodophyllotoxin and fluorouracil

4'-demethyldesoxypodophyllotoxin has been researched along with fluorouracil in 2 studies

Compound Research Comparison

Studies
(4'-demethyldesoxypodophyllotoxin)
Trials
(4'-demethyldesoxypodophyllotoxin)
Recent Studies (post-2010)
(4'-demethyldesoxypodophyllotoxin)
Studies
(fluorouracil)
Trials
(fluorouracil)
Recent Studies (post-2010) (fluorouracil)
160645,5629,30714,663

Protein Interaction Comparison

ProteinTaxonomy4'-demethyldesoxypodophyllotoxin (IC50)fluorouracil (IC50)
Epidermal growth factor receptorHomo sapiens (human)0.32
Thymidylate synthaseMus musculus (house mouse)1.58
AromataseHomo sapiens (human)0.63

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, SW; Ding, YL; Huang, WT; Hui, L; Liu, J; Liu, JF1
Chen, SW; Feng, SL; Guan, XW; Hui, L; Tang, ZB; Xu, XH1

Other Studies

2 other study(ies) available for 4'-demethyldesoxypodophyllotoxin and fluorouracil

ArticleYear
Synthesis and biological evaluation of conjugates of deoxypodophyllotoxin and 5-FU as inducer of caspase-3 and -7.
    European journal of medicinal chemistry, 2012, Volume: 49

    Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 7; Cell Line, Tumor; Drugs, Chinese Herbal; Enzyme Activation; Fluorouracil; G2 Phase Cell Cycle Checkpoints; Humans; M Phase Cell Cycle Checkpoints; Neoplasms; Podophyllotoxin

2012
Synthesis of hybrid 4-deoxypodophyllotoxin-5-fluorouracil compounds that inhibit cellular migration and induce cell cycle arrest.
    Bioorganic & medicinal chemistry letters, 2016, Mar-15, Volume: 26, Issue:6

    Topics: Antineoplastic Agents; Cell Cycle Checkpoints; Cell Line; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Matrix Metalloproteinase 9; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship; Tissue Inhibitor of Metalloproteinase-1

2016