Compounds > 4'-chloroflavone
Page last updated: 2024-09-04

4'-chloroflavone and 4'-methoxyflavone

4'-chloroflavone has been researched along with 4'-methoxyflavone in 7 studies

Compound Research Comparison

Studies
(4'-chloroflavone)		Trials
(4'-chloroflavone)		Recent Studies (post-2010)
(4'-chloroflavone)		Studies
(4'-methoxyflavone)		Trials
(4'-methoxyflavone)		Recent Studies (post-2010) (4'-methoxyflavone)
90535018

Protein Interaction Comparison

ProteinTaxonomy4'-chloroflavone (IC50)4'-methoxyflavone (IC50)
NLRP3 proteinHomo sapiens (human)18.2
Poly [ADP-ribose] polymerase tankyrase-1Homo sapiens (human)0.0709
NeuraminidaseInfluenza A virus (A/Puerto Rico/8/1934(H1N1))8.74
Potassium voltage-gated channel subfamily A member 5Homo sapiens (human)9

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's4 (57.14)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Chi, YS; Dao, TT; Kim, HP; Kim, J; Kim, S; Park, H1
Azqueta, A; Cabrera, M; Castellano, EE; Cerecetto, H; de Ceráin, AL; Falchi, G; González, M; Lavaggi, ML; Monge, A; Piro, OE; Sagrera, G; Seoane, G; Simoens, M; Vidal, A1
Haikarainen, T; Joensuu, P; Koivunen, J; Legala, OE; Lehtiö, L; Narwal, M; Obaji, E; Pihlajaniemi, T; Venkannagari, H1
Batuta, S; Begum, NA; Das, S; Mitra, I; Niharul Alam, M; Roy, K1
Bhakat, S; Ciftci-Yabanoglu, S; Jayaprakash, V; Nayak, BV; Sinha, BN; Soliman, ME; Timiri, AK; Ucar, G1
An, JY; Kim, NJ; Kim, SW; Lee, HH; Lee, J; Lee, KT; Park, JS; Shin, JS; Son, SH; Yoo, HS; Yu, J1
Chintakrindi, AS; Chowdhary, AS; Gohil, DJ; Kanyalkar, MA1

Other Studies

7 other study(ies) available for 4'-chloroflavone and 4'-methoxyflavone

ArticleYear
Synthesis and inhibitory activity against COX-2 catalyzed prostaglandin production of chrysin derivatives.
    Bioorganic & medicinal chemistry letters, 2004, Mar-08, Volume: 14, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Catalysis; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Flavonoids; Isoenzymes; Mice; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Prostaglandins

2004
Synthetic chalcones, flavanones, and flavones as antitumoral agents: biological evaluation and structure-activity relationships.
    Bioorganic & medicinal chemistry, 2007, May-15, Volume: 15, Issue:10

    Topics: Antineoplastic Agents; Cell Line, Tumor; Chalcones; Chromatography, Thin Layer; Chromosome Aberrations; Comet Assay; DNA Damage; DNA, Neoplasm; Drug Screening Assays, Antitumor; Flavones; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Spectrophotometry, Infrared; Structure-Activity Relationship; X-Ray Diffraction

2007
Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity.
    Journal of medicinal chemistry, 2013, Oct-24, Volume: 56, Issue:20

    Topics: Animals; Crystallography, X-Ray; Drug Discovery; Flavones; HEK293 Cells; Heterocyclic Compounds, 3-Ring; Humans; Isoenzymes; L Cells; Mice; Models, Molecular; Molecular Structure; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Binding; Protein Structure, Tertiary; Tankyrases; Wnt Signaling Pathway

2013
Design, synthesis and exploring the quantitative structure-activity relationship of some antioxidant flavonoid analogues.
    Bioorganic & medicinal chemistry letters, 2014, Nov-01, Volume: 24, Issue:21

    Topics: Antioxidants; Drug Design; Flavonoids; Quantitative Structure-Activity Relationship

2014
Monoamine oxidase inhibitory activity of 2-aryl-4H-chromen-4-ones.
    Bioorganic chemistry, 2015, Volume: 58

    Topics: Benzopyrans; Kinetics; Molecular Docking Simulation; Monoamine Oxidase Inhibitors; Proton Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization

2015
Identification and structure activity relationship of novel flavone derivatives that inhibit the production of nitric oxide and PGE
    Bioorganic & medicinal chemistry letters, 2017, 06-01, Volume: 27, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Dinoprostone; Flavones; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; RAW 264.7 Cells; Structure-Activity Relationship

2017
Design, synthesis and biological evaluation of substituted flavones and aurones as potential anti-influenza agents.
    Bioorganic & medicinal chemistry, 2020, 01-01, Volume: 28, Issue:1

    Topics: Antiviral Agents; Benzofurans; Dose-Response Relationship, Drug; Drug Design; Flavones; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship

2020