Compounds > 4'-amino-6-hydroxyflavone
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4'-amino-6-hydroxyflavone and genistein

4'-amino-6-hydroxyflavone has been researched along with genistein in 5 studies

Compound Research Comparison

Studies
(4'-amino-6-hydroxyflavone)		Trials
(4'-amino-6-hydroxyflavone)		Recent Studies (post-2010)
(4'-amino-6-hydroxyflavone)		Studies
(genistein)		Trials
(genistein)		Recent Studies (post-2010) (genistein)
6017,4232042,311

Protein Interaction Comparison

ProteinTaxonomy4'-amino-6-hydroxyflavone (IC50)genistein (IC50)
Chain A, Estrogen receptor 1 (alpha)Homo sapiens (human)0.009
Maltase-glucoamylase, intestinalHomo sapiens (human)2.61
Steroid hormone receptor ERR2Homo sapiens (human)0.395
Tyrosine-protein kinase ABL1Homo sapiens (human)5.5
Epidermal growth factor receptorHomo sapiens (human)1.2
TransthyretinHomo sapiens (human)7.8
Estrogen receptorHomo sapiens (human)1.3477
Steroid hormone receptor ERR1Homo sapiens (human)0.01
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)9.033
17-beta-hydroxysteroid dehydrogenase type 1Homo sapiens (human)2.21
Protein kinase C alpha typeHomo sapiens (human)1
cAMP-dependent protein kinase catalytic subunit alphaHomo sapiens (human)1
Amine oxidase [flavin-containing] AHomo sapiens (human)4.184
Thromboxane-A synthase Homo sapiens (human)7.72
Amine oxidase [flavin-containing] BHomo sapiens (human)3.9333
Dipeptidyl peptidase 4Homo sapiens (human)0.48
Proteasome subunit beta type-5Homo sapiens (human)9.26
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.395
Tyrosine-protein kinase CSKHomo sapiens (human)1
Dual specificity mitogen-activated protein kinase kinase 4Homo sapiens (human)0.4
Xanthine dehydrogenase/oxidaseBos taurus (cattle)1.73
Aldehyde oxidaseHomo sapiens (human)0.34
Integrase Human immunodeficiency virus 11.1
Estrogen receptor betaHomo sapiens (human)0.3706
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)Plasmodium falciparum (malaria parasite P. falciparum)7
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)3.8905
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)7.85
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)9.1201

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chang, CJ; Geahlen, RL1
Burg, DL; Cushman, M; Geahlen, RL; Nagarathnam, D1
Abts, H; Diehl, V; Kube, D; Tesch, H; Von Knethen, A1
Aussel, C; Breittmayer, JP; Dumaurier, MJ; Pelassy, C1
de Almeida, JP; Freitas-Santos, T; Saldanha, C1

Reviews

1 review(s) available for 4'-amino-6-hydroxyflavone and genistein

ArticleYear
Protein-tyrosine kinase inhibition: mechanism-based discovery of antitumor agents.
    Journal of natural products, 1992, Volume: 55, Issue:11

    Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; Protein-Tyrosine Kinases

1992

Other Studies

4 other study(ies) available for 4'-amino-6-hydroxyflavone and genistein

ArticleYear
Synthesis and protein-tyrosine kinase inhibitory activities of flavonoid analogues.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:2

    Topics: Chemical Phenomena; Chemistry; Flavonoids; Genistein; Protein-Tyrosine Kinases; Structure-Activity Relationship

1991
Expression of p56lck in B-cell neoplasias.
    Leukemia & lymphoma, 1997, Volume: 26, Issue:5-6

    Topics: Antibodies, Anti-Idiotypic; B-Lymphocytes; Burkitt Lymphoma; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; HeLa Cells; Hodgkin Disease; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lymphoma, B-Cell; Phosphorylation; Protein Kinase C; Staphylococcus aureus; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1997
Regulation of the serine-base exchange enzyme system by CD4: effects of monoclonal antibodies, jacalin, interleukin 16 and the HIV membrane protein gp120.
    The Biochemical journal, 1998, Jan-01, Volume: 329 ( Pt 1)

    Topics: Antibodies, Monoclonal; CD3 Complex; CD4 Antigens; CD4-Positive T-Lymphocytes; Down-Regulation; Enzyme Inhibitors; Flavonoids; Genistein; HIV Envelope Protein gp120; Humans; Interleukin-16; Jurkat Cells; Kinetics; Lectins; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Nitrogenous Group Transferases; Phosphatidylserines; Phospholipids; Plant Lectins; Recombinant Proteins; Serine; Thapsigargin; Up-Regulation

1998
Evidence that the degree of band 3 phosphorylation modulates human erythrocytes nitric oxide efflux--in vitro model of hyperfibrinogenemia.
    Clinical hemorheology and microcirculation, 2011, Volume: 49, Issue:1-4

    Topics: Anion Exchange Protein 1, Erythrocyte; Biological Transport; Diffusion; Dipeptides; Erythrocyte Membrane; Erythrocytes; Fibrinogen; Flavonoids; Genistein; Glutathione; Humans; Intracellular Signaling Peptides and Proteins; Male; Nitrates; Nitric Oxide; Nitrites; Nitro Compounds; Osmolar Concentration; Phosphorylation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Syk Kinase

2011