Page last updated: 2024-09-05

4',6-dihydroxyflavone and chrysin

4',6-dihydroxyflavone has been researched along with chrysin in 3 studies

Compound Research Comparison

Studies
(4',6-dihydroxyflavone)
Trials
(4',6-dihydroxyflavone)
Recent Studies (post-2010)
(4',6-dihydroxyflavone)
Studies
(chrysin)
Trials
(chrysin)
Recent Studies (post-2010) (chrysin)
10039136646

Protein Interaction Comparison

ProteinTaxonomy4',6-dihydroxyflavone (IC50)chrysin (IC50)
G2/mitotic-specific cyclin-B2Homo sapiens (human)7.1
Cytochrome P450 1A1Homo sapiens (human)0.7215
Cytochrome P450 1A2Homo sapiens (human)0.236
Cyclin-dependent kinase 1Homo sapiens (human)7.1
AromataseHomo sapiens (human)0.667
Cytochrome P450 2C9 Homo sapiens (human)5.225
G2/mitotic-specific cyclin-B1Homo sapiens (human)7.1
Aldo-keto reductase family 1 member B1Homo sapiens (human)8.14
G2/mitotic-specific cyclin-BMarthasterias glacialis (spiny starfish)5.85
Aldo-keto reductase family 1 member B1Bos taurus (cattle)7.79
Carbonyl reductase [NADPH] 1Homo sapiens (human)0.67
Glycogen synthase kinase-3 betaRattus norvegicus (Norway rat)5.85
Casein kinase II subunit alpha'Homo sapiens (human)9
Amine oxidase [flavin-containing] AHomo sapiens (human)1.6
Amine oxidase [flavin-containing] BHomo sapiens (human)1.6
Proteasome subunit beta type-5Homo sapiens (human)5.5
Xanthine dehydrogenase/oxidaseHomo sapiens (human)0.84
Glycogen synthase kinase-3 alphaHomo sapiens (human)7.2
Glycogen synthase kinase-3 betaHomo sapiens (human)7.2
Casein kinase II subunit betaHomo sapiens (human)9
Casein kinase II subunit alphaHomo sapiens (human)9
Xanthine dehydrogenase/oxidaseBos taurus (cattle)1.26
Cyclin-dependent kinase 6Homo sapiens (human)5.88
Cyclin-dependent-like kinase 5 Homo sapiens (human)5.3
Cyclin homologHerpesvirus saimiri (strain 11)5.85
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)5.3
Cytochrome P450 1B1Homo sapiens (human)0.152
Integrase Human immunodeficiency virus 11.4
Casein kinase II subunit alpha 3Homo sapiens (human)9
G2/mitotic-specific cyclin-B3Homo sapiens (human)7.1
3-oxoacyl-acyl-carrier protein reductase Plasmodium falciparum (malaria parasite P. falciparum)10
Cyclin-dependent kinase 1Oryzias latipes (Japanese medaka)5.85
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)2.05

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chang, CJ; Geahlen, RL1
Gavande, N; Hanrahan, JR; Hibbs, DE; Kim, MS; Matin, A; Roubin, RH; Salam, NK; Yang, NX1
Doddareddy, MR; Gavande, N; Groundwater, PW; Hibbs, DE; Matin, A; Nammi, S; Roubin, RH1

Reviews

1 review(s) available for 4',6-dihydroxyflavone and chrysin

ArticleYear
Protein-tyrosine kinase inhibition: mechanism-based discovery of antitumor agents.
    Journal of natural products, 1992, Volume: 55, Issue:11

    Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; Protein-Tyrosine Kinases

1992

Other Studies

2 other study(ies) available for 4',6-dihydroxyflavone and chrysin

ArticleYear
7-Hydroxy-benzopyran-4-one derivatives: a novel pharmacophore of peroxisome proliferator-activated receptor alpha and -gamma (PPARalpha and gamma) dual agonists.
    Journal of medicinal chemistry, 2009, Nov-12, Volume: 52, Issue:21

    Topics: Benzopyrans; Cell Line; Humans; PPAR alpha; PPAR gamma; Structure-Activity Relationship

2009
The discovery of novel isoflavone pan peroxisome proliferator-activated receptor agonists.
    Bioorganic & medicinal chemistry, 2013, Feb-01, Volume: 21, Issue:3

    Topics: Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Discovery; HEK293 Cells; Humans; Isoflavones; Models, Molecular; Molecular Structure; Peroxisome Proliferator-Activated Receptors; Structure-Activity Relationship

2013