Page last updated: 2024-09-05

4',6-dihydroxyflavone and acacetin

4',6-dihydroxyflavone has been researched along with acacetin in 4 studies

Compound Research Comparison

Studies
(4',6-dihydroxyflavone)
Trials
(4',6-dihydroxyflavone)
Recent Studies (post-2010)
(4',6-dihydroxyflavone)
Studies
(acacetin)
Trials
(acacetin)
Recent Studies (post-2010) (acacetin)
10032311159

Protein Interaction Comparison

ProteinTaxonomy4',6-dihydroxyflavone (IC50)acacetin (IC50)
Cytochrome P450 1A1Homo sapiens (human)0.083
Cytochrome P450 1A2Homo sapiens (human)0.1655
Amine oxidase [flavin-containing] AHomo sapiens (human)0.167
Potassium voltage-gated channel subfamily A member 5Homo sapiens (human)3.3
Amine oxidase [flavin-containing] BHomo sapiens (human)0.049
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)0.6967
Mitogen-activated protein kinase 10Homo sapiens (human)5.78
Mitogen-activated protein kinase 14Homo sapiens (human)5.78
Cytochrome P450 1B1Homo sapiens (human)0.011
Inositol hexakisphosphate kinase 2Homo sapiens (human)5.7
Potassium voltage-gated channel subfamily D member 3Homo sapiens (human)9.3

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chang, CJ; Geahlen, RL1
Gavande, N; Hanrahan, JR; Hibbs, DE; Kim, MS; Matin, A; Roubin, RH; Salam, NK; Yang, NX1
Doddareddy, MR; Gavande, N; Groundwater, PW; Hibbs, DE; Matin, A; Nammi, S; Roubin, RH1
Chakraborty, A; Chakraborty, M; Frye, SV; Gu, C; Pearce, KH; Puhl-Rubio, AC; Shears, SB; Stashko, MA; Wang, H; Wang, X1

Reviews

1 review(s) available for 4',6-dihydroxyflavone and acacetin

ArticleYear
Protein-tyrosine kinase inhibition: mechanism-based discovery of antitumor agents.
    Journal of natural products, 1992, Volume: 55, Issue:11

    Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; Protein-Tyrosine Kinases

1992

Other Studies

3 other study(ies) available for 4',6-dihydroxyflavone and acacetin

ArticleYear
7-Hydroxy-benzopyran-4-one derivatives: a novel pharmacophore of peroxisome proliferator-activated receptor alpha and -gamma (PPARalpha and gamma) dual agonists.
    Journal of medicinal chemistry, 2009, Nov-12, Volume: 52, Issue:21

    Topics: Benzopyrans; Cell Line; Humans; PPAR alpha; PPAR gamma; Structure-Activity Relationship

2009
The discovery of novel isoflavone pan peroxisome proliferator-activated receptor agonists.
    Bioorganic & medicinal chemistry, 2013, Feb-01, Volume: 21, Issue:3

    Topics: Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Discovery; HEK293 Cells; Humans; Isoflavones; Models, Molecular; Molecular Structure; Peroxisome Proliferator-Activated Receptors; Structure-Activity Relationship

2013
Inhibition of Inositol Polyphosphate Kinases by Quercetin and Related Flavonoids: A Structure-Activity Analysis.
    Journal of medicinal chemistry, 2019, 02-14, Volume: 62, Issue:3

    Topics: Binding Sites; Crystallography, X-Ray; HCT116 Cells; Humans; Inositol Phosphates; Molecular Structure; Phosphotransferases (Alcohol Group Acceptor); Phosphotransferases (Phosphate Group Acceptor); Protein Binding; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quercetin; Structure-Activity Relationship

2019