Page last updated: 2024-09-03

4',6-dichloroflavan and chalcone

4',6-dichloroflavan has been researched along with chalcone in 9 studies

Compound Research Comparison

Studies
(4',6-dichloroflavan)
Trials
(4',6-dichloroflavan)
Recent Studies (post-2010)
(4',6-dichloroflavan)
Studies
(chalcone)
Trials
(chalcone)
Recent Studies (post-2010) (chalcone)
27342,015221,086

Protein Interaction Comparison

ProteinTaxonomy4',6-dichloroflavan (IC50)chalcone (IC50)
perilipin-5Homo sapiens (human)4.245
perilipin-1Homo sapiens (human)4.194
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform aHomo sapiens (human)4.2195
Amine oxidase [flavin-containing] AHomo sapiens (human)1.41
Amine oxidase [flavin-containing] BHomo sapiens (human)1.41
Sortase AStreptococcus mutans5

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19907 (77.78)18.7374
1990's1 (11.11)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
al-Nakib, W; Andries, K; Dearden, C; Tyrrell, DA; Woestenborghs, R1
Aoyama, M; Ishitsuka, H; Ninomiya, Y; Suhara, Y; Umeda, I1
Phillpotts, RJ; Tyrrell, DA1
Selway, JW1
Diana, GD; McKinlay, MA; Otto, MJ1
Ahmad, AL; Tyrrell, DA1
Ishitsuka, H; Ninomiya, Y; Suhara, Y1
Andries, K; Dewindt, B; van Eemeren, K1
Caleffi, GS; Costa, PRR; Demidoff, FC; Figueiredo, M1

Reviews

3 review(s) available for 4',6-dichloroflavan and chalcone

ArticleYear
Rhinovirus colds.
    British medical bulletin, 1985, Volume: 41, Issue:4

    Topics: Benzimidazoles; Chalcone; Chalcones; Common Cold; Flavonoids; Humans; Interferon Type I; Oximes; Rhinovirus; Sulfonamides

1985
Antiviral activity of flavones and flavans.
    Progress in clinical and biological research, 1986, Volume: 213

    Topics: Animals; Antiviral Agents; Chalcone; Chalcones; Clinical Trials as Topic; Common Cold; Drug Resistance, Microbial; Flavonoids; Hepatitis B; Humans; Mice; Picornaviridae; Rhinovirus; RNA, Viral; Simplexvirus; Structure-Activity Relationship; Viral Vaccines

1986
Inhibitors of picornavirus uncoating as antiviral agents.
    Pharmacology & therapeutics, 1985, Volume: 29, Issue:3

    Topics: Animals; Anti-Infective Agents; Antiviral Agents; Chalcone; Chalcones; Ciprofloxacin; Flavonoids; Fluoroquinolones; Furans; Humans; Isoxazoles; Ketones; Picornaviridae; Picornaviridae Infections; Quinolines; Rhinovirus; Structure-Activity Relationship

1985

Trials

1 trial(s) available for 4',6-dichloroflavan and chalcone

ArticleYear
Antiviral activity of flavones and flavans.
    Progress in clinical and biological research, 1986, Volume: 213

    Topics: Animals; Antiviral Agents; Chalcone; Chalcones; Clinical Trials as Topic; Common Cold; Drug Resistance, Microbial; Flavonoids; Hepatitis B; Humans; Mice; Picornaviridae; Rhinovirus; RNA, Viral; Simplexvirus; Structure-Activity Relationship; Viral Vaccines

1986

Other Studies

6 other study(ies) available for 4',6-dichloroflavan and chalcone

ArticleYear
Drug resistant rhinoviruses from the nose of experimentally treated volunteers.
    Archives of virology, 1989, Volume: 109, Issue:1-2

    Topics: Antiviral Agents; Chalcone; Drug Resistance, Microbial; Flavonoids; Humans; Isoxazoles; Microbial Sensitivity Tests; Nose; Pyridazines; Rhinovirus

1989
Comparative studies on the modes of action of the antirhinovirus agents Ro 09-0410, Ro 09-0179, RMI-15,731, 4',6-dichloroflavan, and enviroxime.
    Antimicrobial agents and chemotherapy, 1985, Volume: 27, Issue:4

    Topics: Antiviral Agents; Benzimidazoles; Binding, Competitive; Cells, Cultured; Centrifugation, Density Gradient; Chalcone; Chalcones; Chloroform; Cytopathogenic Effect, Viral; Drug Resistance, Microbial; Flavonoids; Furans; Humans; Oximes; Quercetin; Rhinovirus; Sulfonamides

1985
Synergism between anti-rhinovirus antivirals: various human interferons and a number of synthetic compounds.
    Antiviral research, 1986, Volume: 6, Issue:4

    Topics: Antiviral Agents; Benzimidazoles; Cell Line; Chalcone; Chalcones; Cytopathogenic Effect, Viral; Drug Synergism; Flavonoids; Humans; Interferon Type I; Interferon-gamma; Oximes; Rhinovirus; Semliki forest virus; Sulfonamides

1986
Molecular basis of drug resistance to new antirhinovirus agents.
    The Journal of antimicrobial chemotherapy, 1986, Volume: 18 Suppl B

    Topics: Benzimidazoles; Capsid; Chalcone; Chalcones; Drug Resistance, Microbial; Flavonoids; Furans; Oximes; Quercetin; Rhinovirus; Sulfonamides

1986
Antiviral capsid-binding compounds can inhibit the adsorption of minor receptor rhinoviruses.
    Antiviral research, 1994, Volume: 25, Issue:1

    Topics: Adsorption; Antiviral Agents; Capsid; Chalcone; Chalcones; Flavonoids; HeLa Cells; Humans; Isoxazoles; Mutation; Protein Conformation; Pyridazines; Receptors, Virus; Rhinovirus

1994
Ru(II)-Catalyzed Asymmetric Transfer Hydrogenation of Chalcones in Water: Application to the Enantioselective Synthesis of Flavans BW683C and Tephrowatsin E.
    The Journal of organic chemistry, 2022, 11-04, Volume: 87, Issue:21

    Topics: Catalysis; Chalcone; Chalcones; Hydrogenation; Polyphenols; Stereoisomerism; Water

2022