Page last updated: 2024-09-05

4',5-dihydroxy-3',6,7,8-tetramethoxyflavone and 5-demethylnobiletin

4',5-dihydroxy-3',6,7,8-tetramethoxyflavone has been researched along with 5-demethylnobiletin in 3 studies

Compound Research Comparison

Studies
(4',5-dihydroxy-3',6,7,8-tetramethoxyflavone)
Trials
(4',5-dihydroxy-3',6,7,8-tetramethoxyflavone)
Recent Studies (post-2010)
(4',5-dihydroxy-3',6,7,8-tetramethoxyflavone)
Studies
(5-demethylnobiletin)
Trials
(5-demethylnobiletin)
Recent Studies (post-2010) (5-demethylnobiletin)
60342033

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beutler, JA; Boyd, MR; Cardellina, JH; Haemers, A; Hamel, E; Rajan, P; Roitman, JN; Vlietinck, AJ1
Kosano, H; Miyata, Y; Natsugari, H; Okuyama, Y; Oshitari, T; Takahashi, H1
Kosano, H; Miyata, Y; Natsugari, H; Okuyama, Y; Oshitari, T; Shimada, A; Takahashi, H1

Other Studies

3 other study(ies) available for 4',5-dihydroxy-3',6,7,8-tetramethoxyflavone and 5-demethylnobiletin

ArticleYear
Structure-activity requirements for flavone cytotoxicity and binding to tubulin.
    Journal of medicinal chemistry, 1998, Jun-18, Volume: 41, Issue:13

    Topics: Antineoplastic Agents, Phytogenic; Biopolymers; Cell Survival; Colchicine; Drug Screening Assays, Antitumor; Flavonoids; Humans; Protein Binding; Structure-Activity Relationship; Tubulin; Tumor Cells, Cultured

1998
B-Ring-modified and/or 5-demethylated nobiletin congeners: inhibitory activity against pro-MMP-9 production.
    Bioorganic & medicinal chemistry, 2011, Dec-01, Volume: 19, Issue:23

    Topics: Cell Line; Enzyme Precursors; Epithelial Cells; Flavones; Humans; Lens, Crystalline; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Protease Inhibitors; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2011
Polymethoxyflavones as agents that prevent formation of cataract: nobiletin congeners show potent growth inhibitory effects in human lens epithelial cells.
    Bioorganic & medicinal chemistry letters, 2013, Jan-01, Volume: 23, Issue:1

    Topics: Cataract; Cell Line; Cell Movement; Cell Proliferation; Citrus; Epithelial Cells; Flavones; Humans; Lens, Crystalline; Matrix Metalloproteinase 9; Structure-Activity Relationship

2013