Compounds > 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone
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4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and warfarin

4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone has been researched along with warfarin in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Smith, TJ; Stoner, GD; Yang, CS1
Anderson, LM; Jones, AB; Liao, AM; Liu, Y; Smith, TJ; Yang, CS1
Funae, Y; Imaida, K; Kamataki, T; Masumura, K; Miyazaki, M; Nohmi, T; Saoo, K; Takeuchi, H; Yamazaki, H; Yokohira, M1
Michno, N; Murphy, SE; Schlicht, KE; Scott, EE; Smith, BD1
Berg, JZ; Murphy, SE; Schlicht, KE1
Cao, B; Feng, M; Liu, S; Mao, J; Zhang, H; Zhang, Q1

Other Studies

6 other study(ies) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and warfarin

ArticleYear
Activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human lung microsomes by cytochromes P450, lipoxygenase, and hydroperoxides.
    Cancer research, 1995, Dec-01, Volume: 55, Issue:23

    Topics: Aldehydes; Arachidonic Acids; Carbon Monoxide; Carcinogens; Coumarins; Cytochrome P-450 Enzyme System; Humans; Hydrogen Peroxide; Lipoxygenase; Lung; Metyrapone; Microsomes; NADP; Nitrosamines; Oxidation-Reduction; Superoxide Dismutase; Temperature

1995
Enzymes involved in the bioactivation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in patas monkey lung and liver microsomes.
    Carcinogenesis, 1997, Volume: 18, Issue:8

    Topics: Animals; Aspirin; Biotransformation; Carbon Monoxide; Coumarins; Cytochrome P-450 Enzyme System; Erythrocebus patas; Female; Isothiocyanates; Lipoxygenase; Lung; Masoprocol; Microsomes; Microsomes, Liver; Nitrosamines; Oxygenases; Prostaglandin-Endoperoxide Synthases

1997
Mechanisms of chemopreventive effects of 8-methoxypsoralen against 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mouse lung adenomas.
    Carcinogenesis, 2005, Volume: 26, Issue:11

    Topics: Adenoma; Animals; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Carcinogens; Chemoprevention; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Escherichia coli Proteins; Female; Humans; Lung Neoplasms; Methoxsalen; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microsomes; Mixed Function Oxygenases; Mutation; Nitrosamines; Pentosyltransferases; Proteins; Salmonella typhimurium; Steroid Hydroxylases

2005
Functional characterization of CYP2A13 polymorphisms.
    Xenobiotica; the fate of foreign compounds in biological systems, 2007, Volume: 37, Issue:12

    Topics: Amino Acid Sequence; Amino Acid Substitution; Aryl Hydrocarbon Hydroxylases; Carcinogens; Coumarins; Humans; Hydroxylation; Nitrosamines; Polymorphism, Genetic; Sequence Deletion

2007
Effect of CYP2A13 active site mutation N297A on metabolism of coumarin and tobacco-specific nitrosamines.
    Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:3

    Topics: Aryl Hydrocarbon Hydroxylases; Catalytic Domain; Chromatography, High Pressure Liquid; Coumarins; Models, Molecular; Mutagenesis, Site-Directed; Nicotiana; Nitrosamines; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Tandem Mass Spectrometry

2009
Effects of 8-methoxypsoralen on the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mice.
    Drug metabolism and pharmacokinetics, 2015, Volume: 30, Issue:4

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carcinogenesis; Carcinogens; Catalysis; Coumarins; Cytochrome P450 Family 2; Female; Hydroxylation; Imidazoles; Methoxsalen; Mice; Mice, Inbred C57BL; Nitrosamines

2015