Compounds > 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone
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4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and pd 98059

4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone has been researched along with pd 98059 in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Deng, X; Flagg, T; Gao, F; Jin, Z1
Deng, X; Xu, L1
Hung, WC; Hung, YH1

Other Studies

3 other study(ies) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and pd 98059

ArticleYear
Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone promotes functional cooperation of Bcl2 and c-Myc through phosphorylation in regulating cell survival and proliferation.
    The Journal of biological chemistry, 2004, Sep-17, Volume: 279, Issue:38

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Antineoplastic Agents; Apoptosis; Bungarotoxins; Carcinogens; Carcinoma, Small Cell; Cell Division; Cell Line, Tumor; Cell Nucleus; Cell Survival; Cisplatin; Enzyme Inhibitors; Flavonoids; Humans; Lung Neoplasms; Mitochondria; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitrosamines; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Receptors, Nicotinic; RNA, Small Interfering; Signal Transduction; Staurosporine

2004
Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induces phosphorylation of mu- and m-calpain in association with increased secretion, cell migration, and invasion.
    The Journal of biological chemistry, 2004, Dec-17, Volume: 279, Issue:51

    Topics: Blotting, Western; Calpain; Carcinogens; Cell Line, Tumor; Cell Movement; Disease Progression; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Flavonoids; Gene Silencing; Genetic Vectors; Humans; Immunoprecipitation; Lung Neoplasms; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Biological; Neoplasm Invasiveness; Neoplasm Metastasis; Nicotiana; Nitrosamines; Phosphorylation; RNA Interference; RNA, Small Interfering; Signal Transduction

2004
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) enhances invasiveness of lung cancer cells by up-regulating contactin-1 via the alpha7 nicotinic acetylcholine receptor/ERK signaling pathway.
    Chemico-biological interactions, 2009, May-15, Volume: 179, Issue:2-3

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Bungarotoxins; Cell Adhesion Molecules, Neuronal; Contactin 1; Contactins; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Profiling; Humans; Lung Neoplasms; Neoplasm Invasiveness; Nitrosamines; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transcription, Genetic; Tumor Cells, Cultured; Up-Regulation

2009