Compounds > 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone
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4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and nadp

4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone has been researched along with nadp in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Smith, TJ; Stoner, GD; Yang, CS1
Collazo, NR; Sultatos, LG1
Atalla, A; Breyer-Pfaff, U; Maser, E1
Hecht, SS; Hochalter, JB; Murphy, SE; Villalta, PW1
D'Agostino, J; Ding, X; Murphy, SE; von Weymarn, L; Wu, H; Zhang, QY; Zhang, X1
Dunford, JE; Skarydova, L; Stambergova, H; Wsol, V1

Other Studies

6 other study(ies) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and nadp

ArticleYear
Activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human lung microsomes by cytochromes P450, lipoxygenase, and hydroperoxides.
    Cancer research, 1995, Dec-01, Volume: 55, Issue:23

    Topics: Aldehydes; Arachidonic Acids; Carbon Monoxide; Carcinogens; Coumarins; Cytochrome P-450 Enzyme System; Humans; Hydrogen Peroxide; Lipoxygenase; Lung; Metyrapone; Microsomes; NADP; Nitrosamines; Oxidation-Reduction; Superoxide Dismutase; Temperature

1995
Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human placental microsomes.
    Biochemical pharmacology, 1995, Nov-27, Volume: 50, Issue:11

    Topics: Alcohol Oxidoreductases; Carcinogens; Computer Simulation; Cytochrome P-450 Enzyme System; Humans; Kinetics; Lung; Microsomes; Microsomes, Liver; NAD; NADP; Nitrosamines; Placenta

1995
Purification and characterization of oxidoreductases-catalyzing carbonyl reduction of the tobacco-specific nitrosamine 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in human liver cytosol.
    Xenobiotica; the fate of foreign compounds in biological systems, 2000, Volume: 30, Issue:8

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adult; Aged; Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Carcinogens; Cytosol; Enzyme Inhibitors; Female; Flufenamic Acid; Humans; Hydroxysteroid Dehydrogenases; Liver; Male; Medroxyprogesterone Acetate; Middle Aged; NAD; NADP; Nicotiana; Nitrosamines; Phenolphthalein; Plants, Toxic; Quercetin; Rutin; Smoke; Vitamin K

2000
2'-Hydroxylation of nicotine by cytochrome P450 2A6 and human liver microsomes: formation of a lung carcinogen precursor.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Nov-07, Volume: 97, Issue:23

    Topics: Aryl Hydrocarbon Hydroxylases; Carcinogens; Cotinine; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Humans; Hydroxy Acids; Hydroxylation; Keto Acids; Lung; Microsomes, Liver; Mixed Function Oxygenases; Molecular Structure; NADP; Nicotine; Nitrosamines; Prodrugs

2000
CYP2A13: variable expression and role in human lung microsomal metabolic activation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 323, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aryl Hydrocarbon Hydroxylases; Biotransformation; Carcinogens; Cytochrome P-450 CYP2A6; Female; Humans; Hydroxylation; Lung; Male; Methoxsalen; Microsomes; Middle Aged; Mixed Function Oxygenases; NADP; Nitrosamines; RNA, Messenger

2007
Biochemical properties of human dehydrogenase/reductase (SDR family) member 7.
    Chemico-biological interactions, 2014, Jan-25, Volume: 207

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Amino Acid Sequence; Animals; Benzaldehydes; Blotting, Western; Fluorescent Antibody Technique; Humans; Intracellular Membranes; Isoenzymes; Kinetics; Microsomes, Liver; Molecular Sequence Data; NAD; NADP; Nitrosamines; Oxidoreductases; Sf9 Cells; Spectrophotometry; Substrate Specificity; Ultracentrifugation

2014