Compounds > 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone
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4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and metyrapone

4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone has been researched along with metyrapone in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Guo, Z; Hong, JY; Ning, SM; Smith, TJ; Thomas, PE; Yang, CS1
Smith, TJ; Stoner, GD; Yang, CS1
El-Bayoumy, K; Leszczynska, J; Prokopczyk, B; Trushin, N; Waggoner, SE1

Other Studies

3 other study(ies) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and metyrapone

ArticleYear
Kinetics and enzyme involvement in the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in microsomes of rat lung and nasal mucosa.
    Carcinogenesis, 1992, Volume: 13, Issue:8

    Topics: Animals; Aspirin; Benzoflavones; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Hydroxylation; In Vitro Techniques; Isoenzymes; Lung; Male; Metyrapone; Microsomes; Nasal Mucosa; Nitrosamines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains

1992
Activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human lung microsomes by cytochromes P450, lipoxygenase, and hydroperoxides.
    Cancer research, 1995, Dec-01, Volume: 55, Issue:23

    Topics: Aldehydes; Arachidonic Acids; Carbon Monoxide; Carcinogens; Coumarins; Cytochrome P-450 Enzyme System; Humans; Hydrogen Peroxide; Lipoxygenase; Lung; Metyrapone; Microsomes; NADP; Nitrosamines; Oxidation-Reduction; Superoxide Dismutase; Temperature

1995
Human cervical tissue metabolizes the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, via alpha-hydroxylation and carbonyl reduction pathways.
    Carcinogenesis, 2001, Volume: 22, Issue:1

    Topics: 11-beta-Hydroxysteroid Dehydrogenases; Carcinogens; Cell Line; Cervix Uteri; Cortisone; Cytosol; Female; Glycyrrhizic Acid; Humans; Hydrocortisone; Hydroxylation; Hydroxysteroid Dehydrogenases; Keto Acids; Kinetics; Metyrapone; Microsomes; Nitrosamines; Oxidation-Reduction; Stereoisomerism; Tritium

2001