Compounds > 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone
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4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and methyl(acetoxymethyl)nitrosamine

4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone has been researched along with methyl(acetoxymethyl)nitrosamine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hecht, SS; Peterson, LA1
Gradia, S; Hecht, SS; Peterson, LA; Ronai, ZA1
Crankshaw, DL; Donaldson, EE; Kenney, PJ; Peterson, LA; Thomson, NM1
Jones, R; Shallop, A; Tretyakova, N; Upadhyaya, P; Ziegel, R1
Augusto, LA; Bissonnette, EY; Castonguay, A; Gaudreault, M; Proulx, LI; Turmel, V1

Other Studies

5 other study(ies) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and methyl(acetoxymethyl)nitrosamine

ArticleYear
O6-methylguanine is a critical determinant of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone tumorigenesis in A/J mouse lung.
    Cancer research, 1991, Oct-15, Volume: 51, Issue:20

    Topics: Animals; Carcinogens; Dimethylnitrosamine; DNA; Female; Guanine; Hydroxylation; Lung Neoplasms; Methylation; Mice; Nitrosamines

1991
G to A transitions and G to T transversions in codon 12 of the Ki-ras oncogene isolated from mouse lung tumors induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and related DNA methylating and pyridyloxobutylating agents.
    Carcinogenesis, 1993, Volume: 14, Issue:11

    Topics: Adenine; Animals; Base Sequence; Carcinogens; Codon; Dimethylnitrosamine; DNA, Neoplasm; Female; Genes, ras; Guanine; Lung Neoplasms; Methylation; Mice; Mice, Inbred A; Nitrosamines; Point Mutation; Polymorphism, Restriction Fragment Length; Pyridines; Thymine

1993
Interactions between methylating and pyridyloxobutylating agents in A/J mouse lungs: implications for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis.
    Cancer research, 2001, Aug-01, Volume: 61, Issue:15

    Topics: Alkylating Agents; Animals; Carcinogens; Dimethylnitrosamine; DNA Methylation; DNA Repair; Drug Synergism; Female; Guanine; Liver; Lung; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines; O(6)-Methylguanine-DNA Methyltransferase; Pyridines

2001
Endogenous 5-methylcytosine protects neighboring guanines from N7 and O6-methylation and O6-pyridyloxobutylation by the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Biochemistry, 2004, Jan-20, Volume: 43, Issue:2

    Topics: 5-Methylcytosine; Base Sequence; Carcinogens; Chromatography, High Pressure Liquid; Deoxyguanosine; Dimethylnitrosamine; DNA Adducts; DNA Methylation; Genes, p53; Guanine; Hydrolysis; Nicotiana; Nitrosamines; Spectrometry, Mass, Electrospray Ionization

2004
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone, a component of tobacco smoke, modulates mediator release from human bronchial and alveolar epithelial cells.
    Clinical and experimental immunology, 2005, Volume: 140, Issue:1

    Topics: Bronchi; Carcinogens; Cell Line; Chemokine CCL2; Cytokines; Dimethylnitrosamine; Dinoprostone; Epithelial Cells; Humans; Hydroxylation; Interleukin-6; Interleukin-8; Nitrosamines; Pulmonary Alveoli; Pyridines

2005