Compounds > 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone
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4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and indole-3-carbinol

4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone has been researched along with indole-3-carbinol in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's3 (25.00)18.2507
2000's3 (25.00)29.6817
2010's5 (41.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amin, SG; Chung, FL; LaGreca, SD; Morse, MA1
Amin, SG; Chung, FL; Hecht, SS; Morse, MA; Wang, CX1
Chung, FL; Eklind, KI; Morse, MA; Xu, Y1
Akerkar, S; Bradlow, HL; Carmella, SG; Garbers, S; Hecht, SS; Taioli, E1
Arakawa, K; Carmella, SG; Hecht, SS; Kenney, PM; Low, SH; Yu, MC1
Anderson, LB; Hecht, SS; Kassie, F; Lahti, D; Scherber, R; Upadhyaya, P; Yu, N1
Hecht, SS; Kassie, F; Matise, I; Negia, M; Upadhyaya, P1
Dagne, A; Kassie, F; Luo, X; Melkamu, T; Qian, X; Schutten, MM; Upadhyaya, P1
Kassie, F; Melkamu, T; Qian, X; Upadhyaya, P1
Balbo, S; Kassie, F; Kirtane, AR; Panyam, J; Qian, X; Song, JM; Teferi, F; Upadhyaya, P1
Kassie, F; Luo, X; Molla, K; O Sullivan, G; Qian, X; Song, JM; Teferi, F; Upadhyaya, P1
Fritz, V; Fujioka, N; Hecht, SS; Kassie, F; Upadhyaya, P1

Reviews

2 review(s) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and indole-3-carbinol

ArticleYear
Inhibition of tobacco-specific nitrosamine-induced lung tumorigenesis by compounds derived from cruciferous vegetables and green tea.
    Annals of the New York Academy of Sciences, 1993, May-28, Volume: 686

    Topics: Adenoma; Animals; Anticarcinogenic Agents; Antioxidants; Carcinogens; Catechin; DNA; DNA Damage; Indoles; Isothiocyanates; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines; Rats; Rats, Inbred F344; Tea; Thiocyanates; Vegetables

1993
Research on cruciferous vegetables, indole-3-carbinol, and cancer prevention: A tribute to Lee W. Wattenberg.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Biomarkers; Brassicaceae; Carcinogens; Cell Line, Tumor; Diet; Disease Models, Animal; Epigenesis, Genetic; Glucosinolates; Humans; Indoles; Lung; Neoplasms; Nitrosamines; Vegetables

2016

Other Studies

10 other study(ies) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and indole-3-carbinol

ArticleYear
Effects of indole-3-carbinol on lung tumorigenesis and DNA methylation induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and on the metabolism and disposition of NNK in A/J mice.
    Cancer research, 1990, May-01, Volume: 50, Issue:9

    Topics: Adenoma; Animals; Carcinogens; DNA; Female; In Vitro Techniques; Indoles; Liver; Lung; Lung Neoplasms; Methylation; Mice; Nitrosamines

1990
Effects of dietary sinigrin or indole-3-carbinol on O6-methylguanine-DNA-transmethylase activity and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA methylation and tumorigenicity in F344 rats.
    Carcinogenesis, 1988, Volume: 9, Issue:10

    Topics: Animals; Carcinogens; Diet; DNA; Glucosinolates; Indoles; Liver Neoplasms; Lung Neoplasms; Male; Methylation; Methyltransferases; Neoplasms, Experimental; Nitrosamines; Nose Neoplasms; O(6)-Methylguanine-DNA Methyltransferase; Pancreatic Neoplasms; Rats; Rats, Inbred F344; Thioglycosides

1988
Effects of indole-3-carbinol on the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in smokers.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1997, Volume: 6, Issue:7

    Topics: Adult; Anticarcinogenic Agents; Biotransformation; Carcinogens; Female; Humans; Indoles; Metabolic Clearance Rate; Nitrosamines; Smoking

1997
Effects of cruciferous vegetable consumption on urinary metabolites of the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in singapore chinese.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2004, Volume: 13, Issue:6

    Topics: Aged; Anticarcinogenic Agents; Carcinogens; China; Female; Glucosinolates; Glucuronides; Humans; Indoles; Lung Neoplasms; Male; Middle Aged; Nicotiana; Nitrosamines; Prospective Studies; Singapore; Smoking; Surveys and Questionnaires; Vegetables

2004
Indole-3-carbinol inhibits 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone plus benzo(a)pyrene-induced lung tumorigenesis in A/J mice and modulates carcinogen-induced alterations in protein levels.
    Cancer research, 2007, Jul-01, Volume: 67, Issue:13

    Topics: Amino Acid Sequence; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogens; Chromatography, Ion Exchange; Chromatography, Liquid; Gene Expression Regulation, Neoplastic; Indoles; Lung Neoplasms; Mass Spectrometry; Mice; Molecular Sequence Data; Nitrosamines

2007
Dose-dependent inhibition of tobacco smoke carcinogen-induced lung tumorigenesis in A/J mice by indole-3-carbinol.
    Cancer prevention research (Philadelphia, Pa.), 2008, Volume: 1, Issue:7

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Benzo(a)pyrene; Blotting, Western; Carcinogens; Cell Proliferation; Chromatography, High Pressure Liquid; Diet; Dose-Response Relationship, Drug; Female; Immunoblotting; Immunohistochemistry; Indoles; Lung Neoplasms; Mice; Nicotiana; Nitrosamines; Smoke

2008
Enhanced inhibition of lung adenocarcinoma by combinatorial treatment with indole-3-carbinol and silibinin in A/J mice.
    Carcinogenesis, 2011, Volume: 32, Issue:4

    Topics: Adenocarcinoma; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Therapy, Combination; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Indoles; Lung Neoplasms; Mice; Nitrosamines; Proto-Oncogene Proteins c-akt; Silybin; Silymarin

2011
Indole-3-carbinol inhibited tobacco smoke carcinogen-induced lung adenocarcinoma in A/J mice when administered during the post-initiation or progression phase of lung tumorigenesis.
    Cancer letters, 2011, Dec-01, Volume: 311, Issue:1

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Anticarcinogenic Agents; Carcinogens; Cell Growth Processes; Cell Transformation, Neoplastic; Female; Humans; Indoles; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Receptor Protein-Tyrosine Kinases

2011
Intranasal delivery of liposomal indole-3-carbinol improves its pulmonary bioavailability.
    International journal of pharmaceutics, 2014, Dec-30, Volume: 477, Issue:1-2

    Topics: Administration, Intranasal; Administration, Oral; Animals; Anticarcinogenic Agents; Biological Availability; Carcinogens; Cytochrome P-450 CYP1A1; Drug Delivery Systems; Female; Gene Expression Regulation, Enzymologic; Indoles; Liposomes; Lung; Lung Neoplasms; Mice; Nitrosamines; Tissue Distribution

2014
Combinations of indole-3-carbinol and silibinin suppress inflammation-driven mouse lung tumorigenesis by modulating critical cell cycle regulators.
    Carcinogenesis, 2015, Volume: 36, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Cyclin D1; Cyclin-Dependent Kinases; Cyclooxygenase 2; Drug Combinations; Female; Humans; I-kappa B Proteins; Indoles; Inflammation; Interleukin-6; Lipopolysaccharides; Lung; Lung Neoplasms; Mice; Mice, Inbred A; NF-KappaB Inhibitor alpha; Nitrosamines; Proto-Oncogene Proteins c-akt; Random Allocation; Retinoblastoma Protein; Silybin; Silymarin; Smoke; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha

2015