Compounds > 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone
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4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and formaldehyde

4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone has been researched along with formaldehyde in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's3 (50.00)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Castonguay, A; Demkowicz-Dobrzanski, K1
Briere, N; Castonguay, A; Pepin, P1
Belinsky, SA; Boucheron, JA; Charbonneau, M; Deal, FH; Richardson, FC; Short, BG; Swenberg, JA1
Gross, EA; Monticello, TM; Morgan, KT1
Cheng, G; Hecht, SS; Villalta, PW; Wang, M1
Cheng, G; Hecht, SS; Upadhyaya, P; Villalta, PW; Wang, M1

Reviews

1 review(s) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and formaldehyde

ArticleYear
Cell proliferation and nasal carcinogenesis.
    Environmental health perspectives, 1993, Volume: 101 Suppl 5

    Topics: Animals; Carcinogens; Cell Division; DNA; Formaldehyde; Humans; Kinetics; Nasal Cavity; Nitrosamines; Nose Neoplasms; Rats

1993

Other Studies

5 other study(ies) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and formaldehyde

ArticleYear
Modulation by glutathione of DNA strand breaks induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its aldehyde metabolites in rat hepatocytes.
    Carcinogenesis, 1992, Volume: 13, Issue:8

    Topics: Analysis of Variance; Animals; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Carcinogens; Cell Survival; Cells, Cultured; Cytochrome P-450 Enzyme System; DNA; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Formaldehyde; Glutathione; Liver; Male; Methionine Sulfoximine; Nitrosamines; Pyridines; Rats; Rats, Inbred F344

1992
Modulation of 4-(methylnitrosamino)-1-(3-pyridyl)-1 butanone demethylation and denitrosation by rat liver microsomes.
    Cancer letters, 1991, Jul-26, Volume: 59, Issue:1

    Topics: Animals; Carcinogens; Catechin; Dimethylnitrosamine; Enzyme Induction; Formaldehyde; Kinetics; Male; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Nitrates; Nitrogen Dioxide; Nitrosamines; Nitrosation; Rats; Rats, Inbred F344

1991
High- to low-dose extrapolation: critical determinants involved in the dose response of carcinogenic substances.
    Environmental health perspectives, 1987, Volume: 76

    Topics: Animals; Carcinogens; Diethylnitrosamine; DNA Damage; Dose-Response Relationship, Drug; Female; Formaldehyde; Gasoline; Male; Mice; Neoplasms, Experimental; Nitrosamines; Rats; Risk

1987
Development of liquid chromatography electrospray ionization tandem mass spectrometry methods for analysis of DNA adducts of formaldehyde and their application to rats treated with N-nitrosodimethylamine or 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Chemical research in toxicology, 2007, Volume: 20, Issue:8

    Topics: Adenosine Deaminase; Animals; Chromatography, High Pressure Liquid; Dimethylnitrosamine; DNA Adducts; Dose-Response Relationship, Drug; Formaldehyde; Hydrolysis; Male; Models, Chemical; Nitrosamines; Rats; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Time Factors

2007
Formation of formaldehyde adducts in the reactions of DNA and deoxyribonucleosides with alpha-acetates of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), and N-nitrosodimethylamine (NDMA).
    Chemical research in toxicology, 2008, Volume: 21, Issue:3

    Topics: Acetates; Carcinogens; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Deoxyribonucleosides; Dimethylnitrosamine; DNA Adducts; Formaldehyde; Nitrosamines; Pyridines; Spectrometry, Mass, Electrospray Ionization

2008