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4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and cotinine

4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone has been researched along with cotinine in 49 studies

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.04)18.7374
1990's12 (24.49)18.2507
2000's16 (32.65)29.6817
2010's19 (38.78)24.3611
2020's1 (2.04)2.80

Authors

AuthorsStudies
Carmella, SG; Foiles, PG; Hecht, SS; Kagan, M; Kagan, SS; Palladino, G; Quart, AM; Quart, E1
Hecht, SS; Hoffmann, D; Lavoie, EJ1
Andersson, G; Björnberg, G; Curvall, M1
Falter, B; Kutzer, C; Richter, E1
Akerkar, S; Brunnemann, KD; Carmella, SG; Hecht, SS; Hoffmann, D; Murphy, SE1
Akerkar, SA; Carmella, SG; Hecht, SS; Richie, JP1
Bombick, BR; Doolittle, DJ; Fulp, C; Lee, CK1
Akerkar, SA; Borukhova, A; Carmella, SG; Hecht, SS1
Akerkar, SA; Carmella, SG; Hecht, SS; Muscat, JE; Richie, JP; Scott, DG1
Foth, H; Kahl, GF; Richter, E; Schrader, E; Schulze, J1
Carmella, SG; Chen, M; Dor Koch, JF; Hatsukami, DK; Hecht, SS; Jensen, JA; Miller, AT; Murphy, SE; Zimmerman, CL1
Ayres, PH; Brown, BG; Chang, CJ; Doolittle, DJ; Lee, CK1
Carmella, SG; Chen, M; Hecht, SS; Lackmann, GM; Salzberger, U; Töllner, U1
Hecht, SS; Hochalter, JB; Murphy, SE; Villalta, PW1
Hee, SS; Yim, SH1
Adgate, JL; Carmella, SG; Church, TR; Fredrickson, A; Greaves, IA; Hecht, SS; Mongin, SJ; Ryan, AD; Sexton, K; Ye, M1
Richter, E; Tricker, AR1
Carmella, SG; Hatsukami, DK; Hecht, SS; Jensen, J; Kramarczuk, I; Le, C; Li, YS; Losey, L; Murphy, SE; Puumala, SS; Roe, MR; Zimmerman, CL1
Adgate, JL; Carmella, SG; Church, TR; Fredrickson, AL; Geisser, MS; Greaves, IA; Hecht, SS; Ramachandran, G; Ryan, AD; Sexton, K1
Bao, Z; Ding, X; He, XY; Hong, JY; Prabhu, S1
Colosimo, S; Djordjevic, MV; Muscat, JE; Richie, JP; Stellman, SD1
Carmella, SG; Hatsukami, DK; Hecht, SS; Lemmonds, C; Murphy, S; Tulunay, OE; Zhang, Y1
Duca, G; Hecht, SS; Mardari, I; Stepanov, I1
An, L; Boettcher, AJ; Carmella, SG; Hecht, SS; Hennrikus, DJ; Koopmeiners, J; Le, C; Le, KA; Murphy, SE1
Feuer, R; Hatsukami, D; Hecht, SS; Jensen, J; Stepanov, I1
Benowitz, NL; Hecht, SS; Jacob, P; Lindgren, B; Stepanov, I; Wilson, M1
Carmella, SG; Hatsukami, DK; Hecht, SS; Le, C; Luo, X; Mooney, M; Murphy, SE; Riley, WT1
Breland, AB; Eissenberg, T; Gray, JN; Weaver, M1
Carmella, SG; Hanson, K; Hatsukami, DK; Hecht, SS; Hertsgaard, LA; Lindgren, BR; Luo, X; Murphy, SE; Riley, WT; Zylla, EB1
Ashley, DL; Bernert, JT; Cummings, KM; Fong, GT; Giovino, GA; Hammond, D; Hatsukami, DK; Jain, RB; King, B; McCraw, JM; McNeill, A; O'Connor, RJ; Polzin, GM; Shahab, L; Watson, CH; Xia, Y; Yan, X; Zhang, L1
Benowitz, NL; Gan, Q; Glantz, SA; Goniewicz, M; Li, X; Lu, W; Xu, J1
Benowitz, N; Eisner, MD; Goniewicz, ML; Havel, C; Jacob, P; Koszowski, B; Lazcano-Ponce, E; Sobczak, A; Zielinska-Danch, W1
Carmella, SG; Hatsukami, DK; Hecht, SS; Hertsgaard, LA; Jensen, JA; Kotlyar, M; Lindgren, BR; Murphy, SE; Stepanov, I1
Ashley, DL; Bernert, JT; Jain, RB; Pirkle, JL; Xia, Y1
Dixon, M; Eldridge, AC; Errington, G; Shepperd, CJ1
Carmella, SG; Chen, M; Davis, AB; Gao, YT; Han, S; Hecht, SS; Moy, KA; Murphy, SE; Nelson, HH; Tao, L; Wang, R; Yu, MC; Yuan, JM; Zhong, Y1
Liang, Q; Sarkar, M; Wang, J1
Balmes, J; Farraro, KF; Hammond, SK; Jenkins, BM; Perrino, C; Schick, SF; Sleiman, M; Trinh, MP; van de Vossenberg, G1
Chao, MR; Chen, JL; Hsu, YW; Hu, CW; Tam, LM1
Butler, LM; Hecht, SS; Stepanov, I; Yuan, JM1
Benowitz, NL; Carmella, SG; Chatfield, DA; Chen, M; Daffa, RM; Hecht, SS; Hovell, MF; Jackson, SR; Jacob, P; Kassem, NO; Liles, S; Matt, GE; Mehta, S; Younis, MA1
Banerjee, A; Baxter, A; Camacho, OM; Minet, E; Sierra, AB; Waters, D1
Hwang, SH; Jeong, BY; Lee, DH; Lim, MK; Park, EY; Yang, W; Yun, EH1
Haiman, CA; Hecht, SS; Kolonel, LN; Le Marchand, L; Murphy, SE; Park, SL; Stram, DO; Wang, H; Wilkens, LR1
Benowitz, NL; Hoh, E; Hovell, MF; Jacob, P; Khan, AM; Matt, GE; Northrup, TF; Stotts, AL1
Fernández, E; Fu, M; Martínez-Sánchez, JM; Pascual, JA; Pérez-Ortuño, R1
da Costa, GG; Loukotková, L; Vanlandingham, M; VonTungeln, LS1
Been, F; Benaglia, L; Covaci, A; Delémont, O; Esseiva, P; Lai, FY; Lympousi, K; Thomaidis, NS; Udrisard, R; van Nuijs, ALN1
Lee, DH; Lee, TS; Oh, JE; Park, MB1

Reviews

1 review(s) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and cotinine

ArticleYear
Urinary tobacco smoke-constituent biomarkers for assessing risk of lung cancer.
    Cancer research, 2014, Jan-15, Volume: 74, Issue:2

    Topics: Biomarkers; Carcinogens; Cotinine; Glucuronides; Humans; Lung Neoplasms; Mass Spectrometry; Multivariate Analysis; Nicotiana; Nicotine; Nitrosamines; Phenanthrenes; Polycyclic Aromatic Hydrocarbons; Prospective Studies; Pyridines; Risk; Risk Assessment; Smoke

2014

Trials

5 trial(s) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and cotinine

ArticleYear
Effects of reduced cigarette smoking on the uptake of a tobacco-specific lung carcinogen.
    Journal of the National Cancer Institute, 2004, Jan-21, Volume: 96, Issue:2

    Topics: Adult; Aged; Alkaloids; Biomarkers, Tumor; Carcinogens; Cotinine; Female; Glucuronates; Humans; Lung Neoplasms; Male; Middle Aged; Nitrosamines; Pyridines; Research Design; Smoking; Smoking Cessation; Treatment Outcome

2004
Similar exposure to a tobacco-specific carcinogen in smokeless tobacco users and cigarette smokers.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2007, Volume: 16, Issue:8

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers; Carcinogens; Cotinine; Creatinine; Female; Humans; Male; Middle Aged; Nitrosamines; Pyridines; Sex Factors; Smoking; Smoking Cessation; Tobacco Use Cessation; Tobacco, Smokeless

2007
Potential reduced exposure products (PREPs) for smokeless tobacco users: clinical evaluation methodology.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2008, Volume: 10, Issue:9

    Topics: Adult; Biomarkers; Carbon Monoxide; Carcinogens; Cotinine; Environmental Monitoring; Female; Harm Reduction; Humans; Inhalation Exposure; Male; Middle Aged; Nicotine; Nitrosamines; Tobacco Use Cessation; Tobacco, Smokeless

2008
Effect of oral snus and medicinal nicotine in smokers on toxicant exposure and withdrawal symptoms: a feasibility study.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2011, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Aged; Carbon Monoxide; Cotinine; Feasibility Studies; Humans; Middle Aged; Nicotine; Nitrosamines; Pyridines; Smoking; Smoking Cessation; Substance Withdrawal Syndrome; Tobacco, Smokeless; Young Adult

2011
A study to evaluate the effect on Mouth Level Exposure and biomarkers of exposure estimates of cigarette smoke exposure following a forced switch to a lower ISO tar yield cigarette.
    Regulatory toxicology and pharmacology : RTP, 2011, Dec-01, Volume: 61, Issue:3 Suppl

    Topics: Acrolein; Adult; Biomarkers; Cotinine; Female; Filtration; Germany; Humans; Inhalation Exposure; Male; Middle Aged; Mouth Mucosa; Nicotiana; Nicotine; Nitrosamines; Pyrenes; Saliva; Smoke; Smoking; Tars; Young Adult

2011

Other Studies

43 other study(ies) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and cotinine

ArticleYear
Mass spectrometric analysis of tobacco-specific nitrosamine hemoglobin adducts in snuff dippers, smokers, and nonsmokers.
    Cancer research, 1990, Sep-01, Volume: 50, Issue:17

    Topics: Adult; Carcinogens; Cotinine; Female; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Male; Nicotiana; Nitrosamines; Plants, Toxic; Smoking; Tobacco, Smokeless

1990
Nicotine: a precursor for carcinogens.
    Cancer letters, 1985, Volume: 26, Issue:1

    Topics: Animals; Biotransformation; Carcinogens; Cotinine; Humans; Lung Neoplasms; Nicotiana; Nicotine; Nitrosamines; Plants, Toxic; Rats; Smoking

1985
Oral mucosal changes and nicotine disposition in users of Swedish smokeless tobacco products: a comparative study.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1994, Volume: 23, Issue:4

    Topics: Adult; Cotinine; Glucuronates; Glucuronic Acid; Humans; Leukoedema, Oral; Male; Middle Aged; Mouth Diseases; Mouth Mucosa; Nicotine; Nitrosamines; Plants, Toxic; Saliva; Sweden; Tobacco, Smokeless

1994
Biomonitoring of hemoglobin adducts: aromatic amines and tobacco-specific nitrosamines.
    The Clinical investigator, 1994, Volume: 72, Issue:5

    Topics: Aminobiphenyl Compounds; Animals; Butanones; Cotinine; Hemoglobinometry; Hemoglobins; Humans; Nicotiana; Nitrosamines; Plants, Toxic; Pyridines; Rats; Smoking; Tobacco, Smokeless

1994
A tobacco-specific lung carcinogen in the urine of men exposed to cigarette smoke.
    The New England journal of medicine, 1993, Nov-18, Volume: 329, Issue:21

    Topics: Adult; Carcinogens; Cotinine; Humans; Lung Neoplasms; Male; Middle Aged; Nitrosamines; Tobacco Smoke Pollution

1993
Intraindividual and interindividual differences in metabolites of the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in smokers' urine.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1995, Volume: 4, Issue:6

    Topics: Adult; Aged; Analysis of Variance; Carcinogens; Cotinine; Creatinine; Female; Gas Chromatography-Mass Spectrometry; Glucuronates; Humans; Male; Middle Aged; Nitrosamines; Radioimmunoassay; Smoking

1995
Inhibition of mutagenicity of N-nitrosamines by tobacco smoke and its constituents.
    Mutation research, 1996, Volume: 367, Issue:2

    Topics: Animals; Antimutagenic Agents; CHO Cells; Cotinine; Cricetinae; Dimethylnitrosamine; Dose-Response Relationship, Drug; Nicotine; Nitrosamines

1996
Analysis of human urine for pyridine-N-oxide metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco-specific lung carcinogen.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1997, Volume: 6, Issue:2

    Topics: Anticarcinogenic Agents; Biomarkers; Biotransformation; Carcinogens; Chromatography, High Pressure Liquid; Cotinine; Creatinine; Enzyme Inhibitors; Glucuronates; Humans; Inactivation, Metabolic; Isothiocyanates; Lung Neoplasms; Mass Spectrometry; Nicotine; Nitrosamines; Proteus mirabilis; Pyridines

1997
Differences in the urinary metabolites of the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in black and white smokers.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1997, Volume: 6, Issue:10

    Topics: Adult; Analysis of Variance; Animals; Biomarkers; Black People; Carcinogens; Cotinine; Creatinine; Female; Glucuronates; Humans; Incidence; Lung Neoplasms; Male; Menthol; Middle Aged; Nicotiana; Nitrosamines; Plants, Toxic; Rats; Smoking; White People

1997
Effect of nicotine or cotinine on metabolism of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in isolated rat lung and liver.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:3

    Topics: Animals; Carcinogens; Cotinine; Liver; Lung; Male; Metabolic Clearance Rate; Nicotine; Nicotinic Agonists; Nitrosamines; Perfusion; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Starvation

1998
Quantitation of urinary metabolites of a tobacco-specific lung carcinogen after smoking cessation.
    Cancer research, 1999, Feb-01, Volume: 59, Issue:3

    Topics: Adult; Animals; Carcinogens; Cotinine; Female; Glucuronates; Humans; Lung Neoplasms; Male; Middle Aged; Nicotine; Nitrosamines; Rats; Rats, Inbred F344; Smoking Cessation

1999
The effect of cotinine or cigarette smoke co-administration on the formation of O6-methylguanine adducts in the lung and liver of A/J mice treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)
    Toxicological sciences : an official journal of the Society of Toxicology, 1999, Volume: 47, Issue:1

    Topics: Animals; Chromatography, High Pressure Liquid; Cotinine; DNA Adducts; Dose-Response Relationship, Drug; Drug Interactions; Female; Guanine; Liver; Lung; Mice; Mutagens; Nitrosamines; Tobacco Smoke Pollution

1999
Metabolites of a tobacco-specific carcinogen in urine from newborns.
    Journal of the National Cancer Institute, 1999, Mar-03, Volume: 91, Issue:5

    Topics: Adult; Carcinogens; Cotinine; Female; Gas Chromatography-Mass Spectrometry; Glucuronates; Humans; Infant, Newborn; Nicotine; Nitrosamines; Pregnancy; Prenatal Exposure Delayed Effects; Smoking

1999
2'-Hydroxylation of nicotine by cytochrome P450 2A6 and human liver microsomes: formation of a lung carcinogen precursor.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Nov-07, Volume: 97, Issue:23

    Topics: Aryl Hydrocarbon Hydroxylases; Carcinogens; Cotinine; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Humans; Hydroxy Acids; Hydroxylation; Keto Acids; Lung; Microsomes, Liver; Mixed Function Oxygenases; Molecular Structure; NADP; Nicotine; Nitrosamines; Prodrugs

2000
Bacterial mutagenicity of some tobacco aromatic nitrogen bases and their mixtures.
    Mutation research, 2001, May-31, Volume: 492, Issue:1-2

    Topics: Animals; Carcinogens; Cotinine; Cricetinae; Dose-Response Relationship, Drug; Drug Interactions; Microsomes, Liver; Mutagenicity Tests; Mutagens; Nicotiana; Nicotine; Nitrosamines; Plants, Toxic; Rats; Rats, Sprague-Dawley; Salmonella typhimurium; Vibrio

2001
Metabolites of a tobacco-specific lung carcinogen in the urine of elementary school-aged children.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2001, Volume: 10, Issue:11

    Topics: Biomarkers; Carcinogens; Child; Cotinine; Environmental Monitoring; Female; Glucuronates; Humans; Male; Nitrosamines; Tobacco Smoke Pollution

2001
Effect of nicotine, cotinine and phenethyl isothiocyanate on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism in the Syrian golden hamster.
    Toxicology, 2002, Sep-30, Volume: 179, Issue:1-2

    Topics: Animals; Biotransformation; Cotinine; Cricetinae; DNA Damage; Female; Glucuronides; Isothiocyanates; Mesocricetus; Nicotiana; Nicotine; Nicotinic Agonists; Nitrosamines

2002
Children's exposure to environmental tobacco smoke: using diverse exposure metrics to document ethnic/racial differences.
    Environmental health perspectives, 2004, Volume: 112, Issue:3

    Topics: Biomarkers; Caregivers; Child; Cotinine; Data Collection; Epidemiologic Studies; Ethnicity; Female; Glucuronates; Humans; Male; Nitrosamines; Poverty; Pyridines; Racial Groups; Reproducibility of Results; Surveys and Questionnaires; Tobacco Smoke Pollution

2004
Metabolism of nicotine and cotinine by human cytochrome P450 2A13.
    Drug metabolism and disposition: the biological fate of chemicals, 2005, Volume: 33, Issue:2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carcinogens; Cotinine; Dose-Response Relationship, Drug; Humans; Insecta; Microsomes; Nicotine; Nitrosamines; Substrate Specificity

2005
Racial differences in exposure and glucuronidation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    Cancer, 2005, Apr-01, Volume: 103, Issue:7

    Topics: Adult; Black People; Carcinogens; Cotinine; Female; Glucuronates; Humans; Male; Middle Aged; Nitrosamines; Pyridines; Racial Groups; Smoking; Thiocyanates; Tobacco Smoke Pollution; White People

2005
Urinary metabolites of a tobacco-specific lung carcinogen in nonsmoking hospitality workers.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2005, Volume: 14, Issue:5

    Topics: Adolescent; Adult; Air Pollutants, Occupational; Biomarkers; Carcinogens; Cotinine; Creatinine; Female; Glucuronates; Humans; Interviews as Topic; Lung Neoplasms; Male; Middle Aged; Nicotine; Nitrosamines; Pyridines; Restaurants; Tobacco Smoke Pollution; Workforce

2005
Uptake of the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by Moldovan children.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2006, Volume: 15, Issue:1

    Topics: Adenocarcinoma; Biomarkers; Carcinogens; Child; Child, Preschool; Cotinine; Environmental Exposure; Female; Humans; Lung Neoplasms; Male; Moldova; Nitrosamines; Rural Population; Tobacco Smoke Pollution; Urban Population

2006
4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol and its glucuronides in the urine of infants exposed to environmental tobacco smoke.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2006, Volume: 15, Issue:5

    Topics: Biomarkers; Chromatography, High Pressure Liquid; Cotinine; Creatinine; Female; Glucuronides; Humans; Infant; Male; Mothers; Nicotine; Nitrosamines; Statistics, Nonparametric; Tobacco Smoke Pollution

2006
Mass spectrometric quantitation of nicotine, cotinine, and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in human toenails.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2006, Volume: 15, Issue:12

    Topics: Cotinine; Gas Chromatography-Mass Spectrometry; Humans; Nails; Nicotine; Nitrosamines; Sensitivity and Specificity

2006
Relationship of human toenail nicotine, cotinine, and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol to levels of these biomarkers in plasma and urine.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2007, Volume: 16, Issue:7

    Topics: Adult; Aged; Biomarkers; Cotinine; Endpoint Determination; Environmental Exposure; Female; Ganglionic Stimulants; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagents; Inhalation Exposure; Longitudinal Studies; Male; Middle Aged; Nails; Nicotine; Nitrosamines; Sensitivity and Specificity; Smoking

2007
Exposure to a tobacco-specific lung carcinogen in adolescent versus adult smokers.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:12

    Topics: Adolescent; Adult; Biomarkers; Carcinogens; Chi-Square Distribution; Cotinine; Cross-Sectional Studies; Female; Humans; Lung; Male; Nitrosamines; Smoking; Surveys and Questionnaires

2008
Effect of differing levels of tobacco-specific nitrosamines in cigarette smoke on the levels of biomarkers in smokers.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2010, Volume: 19, Issue:6

    Topics: Adolescent; Adult; Biomarkers; Cotinine; Female; Humans; Male; Middle Aged; Nicotiana; Nicotine; Nitrosamines; Pyridines; Saliva; Smoking; Young Adult

2010
Chinese 'low-tar' cigarettes do not deliver lower levels of nicotine and carcinogens.
    Tobacco control, 2010, Volume: 19, Issue:5

    Topics: Adult; Carcinogens; China; Consumer Product Safety; Cotinine; Humans; Male; Middle Aged; Nicotiana; Nicotine; Nitrosamines; Polycyclic Aromatic Hydrocarbons; Smoking; Surveys and Questionnaires; Tars

2010
Urine cotinine underestimates exposure to the tobacco-derived lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in passive compared with active smokers.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2010, Volume: 19, Issue:11

    Topics: Adult; Biomarkers; Carcinogens; Chromatography, Liquid; Cotinine; Female; Humans; Male; Middle Aged; Nitrosamines; Pyridines; Smoking; Tandem Mass Spectrometry; Tobacco Smoke Pollution

2010
Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in smokers in the United States: NHANES 2007-2008.
    Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 2011, Volume: 16, Issue:2

    Topics: Adolescent; Adult; Aged; Biomarkers; Black People; Carcinogens; Cotinine; Creatinine; Female; Humans; Male; Middle Aged; Nicotiana; Nicotine; Nitrosamines; Nutrition Surveys; Pyridines; Smoking; Tars; United States; White People; Young Adult

2011
Urinary levels of cigarette smoke constituent metabolites are prospectively associated with lung cancer development in smokers.
    Cancer research, 2011, Nov-01, Volume: 71, Issue:21

    Topics: Aged; China; Cotinine; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nicotiana; Nicotine; Nitrosamines; Phenanthrenes; Prospective Studies; Pyridines; Smoke; Smoking

2011
Metabolism of nicotine and 4-(methylnitrosamino)-l-(3-pyridyl)-lbutanone (NNK) in menthol and non-menthol cigarette smokers.
    Drug metabolism letters, 2012, Sep-01, Volume: 6, Issue:3

    Topics: Adult; Black or African American; Cotinine; Cross-Sectional Studies; Female; Glucuronides; Humans; Male; Menthol; Middle Aged; Nicotine; Nitrosamines; Pyridines; Smoking; Tobacco Products; White People; Young Adult

2012
Thirdhand cigarette smoke in an experimental chamber: evidence of surface deposition of nicotine, nitrosamines and polycyclic aromatic hydrocarbons and de novo formation of NNK.
    Tobacco control, 2014, Volume: 23, Issue:2

    Topics: Administration, Inhalation; Carcinogens; Cotinine; Dust; Environmental Exposure; Humans; Nicotiana; Nicotine; Nitrosamines; Polycyclic Aromatic Hydrocarbons; Skin Absorption; Smoking; Tobacco Smoke Pollution

2014
Direct analysis of tobacco-specific nitrosamine NNK and its metabolite NNAL in human urine by LC-MS/MS: evidence of linkage to methylated DNA lesions.
    Archives of toxicology, 2014, Volume: 88, Issue:2

    Topics: Adenine; Adult; Biomarkers; Chromatography, Liquid; Cotinine; DNA Methylation; Guanine; Humans; Limit of Detection; Nicotine; Nitrosamines; Pyridines; Sensitivity and Specificity; Smoking; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2014
Children's exposure to secondhand and thirdhand smoke carcinogens and toxicants in homes of hookah smokers.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2014, Volume: 16, Issue:7

    Topics: Acetylcysteine; Air; Biomarkers; Carcinogens; Child, Preschool; Cotinine; Cross-Sectional Studies; Environmental Exposure; Family Characteristics; Female; Housing; Humans; Male; Nicotine; Nitrosamines; Pyridines; Smoking; Tobacco Smoke Pollution

2014
Nicotine, cotinine, and b-nicotyrine inhibit NNK-induced DNA-strand break in the hepatic cell line HepaRG.
    Toxicology in vitro : an international journal published in association with BIBRA, 2014, Volume: 28, Issue:7

    Topics: Cell Line, Tumor; Cells, Cultured; Comet Assay; Cotinine; Cytochrome P-450 CYP2A6; DNA Damage; Epithelial Cells; Gene Expression Profiling; Humans; Liver; Nitrosamines; Pyridines

2014
Consequences of Incomplete Smoke-Free Legislation in the Republic of Korea: Results from Environmental and Biochemical Monitoring: Community Based Study.
    Cancer research and treatment, 2016, Volume: 48, Issue:1

    Topics: Air; Air Pollution, Indoor; Cotinine; Environmental Exposure; Environmental Monitoring; Hair; Humans; Nicotine; Nitrosamines; Particulate Matter; Private Facilities; Public Facilities; Republic of Korea; Schools; Tobacco Smoke Pollution; Toilet Facilities

2016
Associations Between Genetic Ancestries and Nicotine Metabolism Biomarkers in the Multiethnic Cohort Study.
    American journal of epidemiology, 2015, Dec-01, Volume: 182, Issue:11

    Topics: Aged; Asian People; Biomarkers; Black or African American; Cohort Studies; Cotinine; Female; Humans; Indians, North American; Male; Middle Aged; Native Hawaiian or Other Pacific Islander; Nicotine; Nitrosamines; Racial Groups; Smoking; White People

2015
Thirdhand smoke contamination in hospital settings: assessing exposure risk for vulnerable paediatric patients.
    Tobacco control, 2016, Volume: 25, Issue:6

    Topics: Carcinogens; Cotinine; Environmental Exposure; Environmental Monitoring; Female; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Nicotine; Nitrosamines; Pregnancy; Tobacco Smoke Pollution

2016
Evaluation of tobacco specific nitrosamines exposure by quantification of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human hair of non-smokers.
    Scientific reports, 2016, 04-26, Volume: 6

    Topics: Cotinine; Hair; Humans; Nicotine; Nitrosamines; Tobacco Smoke Pollution

2016
A simple and highly sensitive UPLC-ESI-MS/MS method for the simultaneous quantification of nicotine, cotinine, and the tobacco-specific carcinogens N'-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in serum samples.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2018, Jan-01, Volume: 1072

    Topics: Carcinogens; Chromatography, High Pressure Liquid; Cotinine; Drug Stability; Humans; Limit of Detection; Linear Models; Nicotine; Nitrosamines; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2018
Levels of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in raw wastewater as an innovative perspective for investigating population-wide exposure to third-hand smoke.
    Scientific reports, 2018, 09-05, Volume: 8, Issue:1

    Topics: Alkaloids; Anabasine; Belgium; Carcinogens; Cotinine; Greece; Humans; Nitrosamines; Public Health; Pyridines; Switzerland; Tobacco Products; Tobacco Smoke Pollution; Wastewater

2018
Does the implementation of smoke-free laws and smoking culture affect exposure to tobacco smoking? Results from 3 hospitality settings in South Korea.
    International journal of occupational medicine and environmental health, 2021, Jan-07, Volume: 34, Issue:1

    Topics: Adult; Aged; Air Pollution, Indoor; Cotinine; Cross-Sectional Studies; Dust; Female; Hair; Humans; Male; Middle Aged; Nicotine; Nitrosamines; Occupational Exposure; Republic of Korea; Restaurants; Smoke-Free Policy; Tobacco Smoke Pollution

2021