Compounds > 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone
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4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and arachidonic acid

4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone has been researched along with arachidonic acid in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Castonguay, A; Rioux, N2
Plummer, H; Schuller, HM; Tithof, PK; Williams, M1
Andrews, R; Barnhill, M; Elgayyar, M; Schuller, HM; Tithof, PK1
Castonguay, A; Miller, MS; Schuller, HM; Walker, K; Weddle, DL; Zhang, L1

Other Studies

5 other study(ies) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and arachidonic acid

ArticleYear
Inhibitors of lipoxygenase: a new class of cancer chemopreventive agents.
    Carcinogenesis, 1998, Volume: 19, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Arachidonic Acid; Aspirin; Body Weight; Carcinogens; Drug Screening Assays, Antitumor; Female; Hydroxyurea; Indoles; Lipoxygenase Inhibitors; Lung Neoplasms; Mice; Mice, Inbred A; Neoplasms, Experimental; Nitrosamines

1998
The tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone is a beta-adrenergic agonist and stimulates DNA synthesis in lung adenocarcinoma via beta-adrenergic receptor-mediated release of arachidonic acid.
    Cancer research, 1999, Sep-15, Volume: 59, Issue:18

    Topics: Adenocarcinoma; Adrenergic beta-Agonists; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Carcinogens; CHO Cells; Cricetinae; DNA Replication; DNA, Neoplasm; Humans; Indoles; Lipoxygenase Inhibitors; Lung Neoplasms; Mice; Nitrosamines; Radioligand Assay; Receptors, Adrenergic, beta; Reverse Transcriptase Polymerase Chain Reaction; Transfection; Tumor Cells, Cultured

1999
The induction of cyclooxygenase-1 by a tobacco carcinogen in U937 human macrophages is correlated to the activation of NF-kappaB.
    Carcinogenesis, 2000, Volume: 21, Issue:9

    Topics: Arachidonic Acid; Biotransformation; Carcinogens; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; DNA-Binding Proteins; Enzyme Induction; Humans; I-kappa B Proteins; Isoenzymes; Macrophages; Membrane Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Nicotiana; Nitrosamines; Plants, Toxic; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate; U937 Cells

2000
4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a nicotine derivative, induces apoptosis of endothelial cells.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:5

    Topics: Animals; Aorta; Apoptosis; Arachidonic Acid; Arteriosclerosis; Carcinogens; Endothelium, Vascular; In Situ Nick-End Labeling; Nicotine; Nitrosamines; Receptors, Adrenergic, beta; Smoking; Swine; Tritium

2001
The cyclooxygenase inhibitor ibuprofen and the FLAP inhibitor MK886 inhibit pancreatic carcinogenesis induced in hamsters by transplacental exposure to ethanol and the tobacco carcinogen NNK.
    Journal of cancer research and clinical oncology, 2002, Volume: 128, Issue:10

    Topics: Adenocarcinoma; Animals; Arachidonic Acid; Cricetinae; Cyclooxygenase Inhibitors; DNA Primers; Ethanol; Female; Genes, p53; Genes, ras; Ibuprofen; Indoles; Lipoxygenase Inhibitors; Male; Maternal-Fetal Exchange; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Pregnancy

2002