4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone has been researched along with 7-methylguanine in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Murphy, SE | 1 |
| Adams, JD; Hoffmann, D; LaVoie, EJ; Prokopczyk, G | 1 |
| Carmella, SG; Chung, FL; Foiles, PG; Hecht, SS; Lin, D; Rubin, JM; Trushin, N | 1 |
| Castonguay, A; Hecht, SS; Rivenson, A; Trushin, N | 1 |
| Anderson, M; Belinsky, SA; Boucheron, JA; Richardson, FC; Swenberg, JA; White, CM | 1 |
| den Engelse, L; Feron, VJ; Leeman, WR; Scherer, E; Van Benthem, J; Vermeulen, E; Wilmer, JW | 1 |
| Bianchini, F; Wild, CP | 1 |
| Hemminki, K; Mustonen, R; Schoket, B | 1 |
| Jones, R; Shallop, A; Tretyakova, N; Ziegel, R | 1 |
| Hecht, SS; Jalas, JR; Kenney, PM; McIntee, EJ; Peterson, LA; Upadhyaya, P | 1 |
| Jones, R; Rajesh, M; Tretyakova, N; Wang, G | 1 |
| Hu, ML; Huang, CS; Wang, WY; Yeh, SL | 1 |
| Chang, LW; Chung, CJ; Hsieh, DP; Hsueh, YM; Lee, HL; Lin, P; Liou, SH; Pu, YS | 1 |
| Chao, MR; Chen, JL; Hsu, YW; Hu, CW; Tam, LM | 1 |
14 other study(ies) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and 7-methylguanine
| Article | Year |
|---|---|
DNA isolation from small tissue samples using anion-exchange HPLC.
Topics: Animals; Carcinogens; Chromatography, High Pressure Liquid; DNA; Guanine; Indicators and Reagents; Lymphocytes; Male; Methylation; Microchemistry; Nitrosamines; Organ Specificity; Rats; Rats, Inbred F344 | 1989 |
Effect of snuff and nicotine on DNA methylation by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
Topics: Animals; DNA; Guanine; Liver; Lung; Male; Mathematics; Methylation; Mouth; Nasal Mucosa; Nicotiana; Nicotine; Nitrosamines; Plants, Toxic; Rats; Rats, Inbred F344; Tobacco, Smokeless | 1987 |
Investigations on the molecular dosimetry of tobacco-specific N-nitrosamines.
Topics: Animals; DNA; Guanine; Hemoglobins; Humans; Liver; Lung; Mutagenicity Tests; Nasal Mucosa; Nicotiana; Nitrosamines; Plants, Toxic; Rats; Tobacco, Smokeless | 1987 |
Comparative tumorigenicity and DNA methylation in F344 rats by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N-nitrosodimethylamine.
Topics: Animals; Dimethylnitrosamine; DNA, Neoplasm; Guanine; Liver Neoplasms; Lung Neoplasms; Male; Methylation; Neoplasms, Experimental; Nicotiana; Nitrosamines; Nose Neoplasms; Plants, Toxic; Rats | 1986 |
Accumulation and persistence of DNA adducts in respiratory tissue of rats following multiple administrations of the tobacco specific carcinogen 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone.
Topics: Animals; Carcinogens; DNA; Guanine; Liver; Lung; Male; Methyltransferases; Nasal Mucosa; Nicotiana; Nitrosamines; O(6)-Methylguanine-DNA Methyltransferase; Plants, Toxic; Rats; Rats, Inbred F344; Respiratory System; Thymidine | 1986 |
Immunocytochemical identification of DNA adducts, O6-methylguanine and 7-methylguanine, in respiratory and other tissues of rat, mouse and Syrian hamster exposed to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
Topics: Animals; Biotransformation; Carcinogens; Cell Nucleus; Cricetinae; DNA; DNA Adducts; DNA Damage; Guanine; Immunohistochemistry; Liver; Lung; Male; Mesocricetus; Methylation; Mice; Nasal Cavity; Nitrosamines; Rats; Rats, Sprague-Dawley; Respiratory System; Staining and Labeling; Trachea | 1994 |
Comparison of 7-medG formation in white blood cells, liver and target organs in rats treated with methylating carcinogens.
Topics: 1,2-Dimethylhydrazine; Alkylating Agents; Animals; Carcinogens; Dimethylhydrazines; Dimethylnitrosamine; DNA; Guanine; Leukocytes; Liver; Male; Methylation; Nitrosamines; Rats | 1994 |
Smoking-related DNA adducts: 32P-postlabeling analysis of 7-methylguanine in human bronchial and lymphocyte DNA.
Topics: Adult; Aged; Bronchi; Carcinogens; DNA; DNA Damage; Female; Guanine; Humans; Lymphocytes; Male; Middle Aged; Nitrosamines; Phosphorus Radioisotopes; Smoking | 1993 |
K-ras gene sequence effects on the formation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-DNA adducts.
Topics: Base Sequence; Carcinogens; Chromatography, High Pressure Liquid; DNA Adducts; Genes, ras; Guanine; Humans; Nitrosamines; Smoking; Time Factors | 2003 |
Stereospecific deuterium substitution attenuates the tumorigenicity and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carcinogens; Cytochrome P-450 CYP2A6; Deuterium; DNA; DNA Adducts; Dose-Response Relationship, Drug; Female; Guanine; Lung; Lung Neoplasms; Mice; Mice, Inbred A; Microsomes; Mixed Function Oxygenases; Molecular Structure; Nitrosamines; Stereoisomerism; Structure-Activity Relationship | 2003 |
Stable isotope labeling-mass spectrometry analysis of methyl- and pyridyloxobutyl-guanine adducts of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in p53-derived DNA sequences.
Topics: Base Sequence; Biotransformation; Carbon Isotopes; Carcinogens; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA Adducts; DNA Mutational Analysis; Exons; Genes, p53; Guanine; Guanosine; Nicotiana; Nitrogen Isotopes; Nitrosamines; Spectrometry, Mass, Electrospray Ionization | 2005 |
Flavonoids suppresses the enhancing effect of beta-carotene on DNA damage induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in A549 cells.
Topics: beta Carotene; DNA Damage; Drug Antagonism; Drug Combinations; Epithelial Cells; Flavanones; Flavonoids; Guanine; Humans; Nitrosamines; Quercetin; Reactive Oxygen Species; Respiratory Mucosa; Rutin | 2006 |
Correlation between the urine profile of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolites and N7-methylguanine in urothelial carcinoma patients.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Carcinogens; Female; Guanine; Humans; Male; Middle Aged; Nitrosamines; Pyridines; Smoking; Surveys and Questionnaires; Urinary Bladder Neoplasms | 2008 |
Direct analysis of tobacco-specific nitrosamine NNK and its metabolite NNAL in human urine by LC-MS/MS: evidence of linkage to methylated DNA lesions.
Topics: Adenine; Adult; Biomarkers; Chromatography, Liquid; Cotinine; DNA Methylation; Guanine; Humans; Limit of Detection; Nicotine; Nitrosamines; Pyridines; Sensitivity and Specificity; Smoking; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2014 |