4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosoamino)-4-(3-pyridyl)-1-butanol

4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone has been researched along with 4-(methylnitrosoamino)-4-(3-pyridyl)-1-butanol in 15 studies

Research

Studies (15)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (6.67)	18.7374
1990's	14 (93.33)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Guengerich, FP; Inui, Y; Shimada, T; Yamazaki, H; Yun, CH	1
Bartsch, H; Brouet, I; Faustman, EM; Friesen, M; Idris, AM; Nair, J; Ohshima, H	1
Choi, CI; Hecht, SS; Jordan, KG; Trushin, N	1
Amin, S; Hecht, SS; Hoffmann, D; Prokopczyk, B; Rivenson, A	1
Carmella, SG; Foiles, PG; Hecht, SS; Murphy, SE	1
Anderson, A; Castonguay, A; Desrochers, M; Lacroix, D	1
Akerkar, SA; Borukhova, A; Carmella, SG; Chung, FL; Hecht, SS; Richie, JP; Skowronski, L	1
Richter, E; Schläger, W; Schulze, J; Wünsch, R	1
Friebertshäuser, J; Maser, E; Richter, E	1
Borukhova, A; Carmella, SG; Desai, D; Hecht, SS	1
Akerkar, SA; Carmella, SG; Hecht, SS; Muscat, JE; Richie, JP; Scott, DG	1
Hecht, SS	1
Carmella, SG; Chen, M; Dor Koch, JF; Hatsukami, DK; Hecht, SS; Jensen, JA; Miller, AT; Murphy, SE; Zimmerman, CL	1
Carmella, SG; Hecht, SS; Upadhyaya, P; Ye, M	1
Atalla, A; Maser, E	1

Reviews

2 review(s) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosoamino)-4-(3-pyridyl)-1-butanol

Article	Year
Biomarkers for human uptake and metabolic activation of tobacco-specific nitrosamines. Cancer research, 1994, Apr-01, Volume: 54, Issue:7 Suppl Topics: Animals; Biological Transport; Biomarkers; Biotransformation; Carcinogens; Humans; Nicotiana; Nitrosamines; Plants, Toxic; Primates; Rodentia; Smoking; Tobacco, Smokeless	1994
Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines. Chemical research in toxicology, 1998, Volume: 11, Issue:6 Topics: Animals; Carcinogens; DNA Adducts; DNA Damage; Genes, p53; Genes, ras; Hemoglobins; Humans; Lung Neoplasms; Mutation; Nitrosamines	1998

Other Studies

13 other study(ies) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosoamino)-4-(3-pyridyl)-1-butanol

Article	Year
Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes. Carcinogenesis, 1992, Volume: 13, Issue:10 Topics: Animals; Antibodies; Biotransformation; Carcinogens; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Dimethylnitrosamine; Enzyme Activation; Humans; Microsomes, Liver; Nicotiana; Nitrosamines; Oxidoreductases, N-Demethylating; Oxygenases; Plants, Toxic; Rabbits	1992
Carcinogenic tobacco-specific nitrosamines are present at unusually high levels in the saliva of oral snuff users in Sudan. Carcinogenesis, 1992, Volume: 13, Issue:6 Topics: Adolescent; Adult; Aged; Humans; Middle Aged; Nitrosamines; Plants, Toxic; Saliva; Sudan; Tobacco, Smokeless	1992
Effects of deuterium substitution on the tumorigenicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in A/J mice. Carcinogenesis, 1990, Volume: 11, Issue:6 Topics: Adenoma; Animals; Carcinogens; Deuterium; DNA; Female; Guanine; Lung; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines; Structure-Activity Relationship	1990
Induction of lung and exocrine pancreas tumors in F344 rats by tobacco-specific and Areca-derived N-nitrosamines. Cancer research, 1988, Dec-01, Volume: 48, Issue:23 Topics: Animals; Areca; Carcinogens; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Nicotiana; Nitrosamines; Nitroso Compounds; Nose Neoplasms; Pancreatic Neoplasms; Plants, Medicinal; Plants, Toxic; Rats; Rats, Inbred F344	1988
Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human kidney epithelial cells transfected with rat CYP2B1 cDNA. Carcinogenesis, 1993, Volume: 14, Issue:8 Topics: Animals; Biotransformation; Carcinogens; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; DNA; Epithelial Cells; Epithelium; Humans; Hydroxylation; Kidney; Male; Nitrosamines; Oxidoreductases; Rats; Transfection	1993
Effects of watercress consumption on metabolism of a tobacco-specific lung carcinogen in smokers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1995, Volume: 4, Issue:8 Topics: Adult; Anticarcinogenic Agents; Carcinogens; Female; Follow-Up Studies; Glucuronates; Humans; Isothiocyanates; Lung Neoplasms; Male; Nitrosamines; Prognosis; Smoking; Vegetables	1995
Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by hamster, mouse and rat intestine: relevance of species differences. Carcinogenesis, 1996, Volume: 17, Issue:5 Topics: Animals; Carcinogens; Cricetinae; Female; Intestinal Mucosa; Male; Mesocricetus; Mice; Nitrosamines; Perfusion; Rats; Rats, Sprague-Dawley; Sex Factors; Species Specificity	1996
The identification of 11 beta-hydroxysteroid dehydrogenase as carbonyl reductase of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. European journal of biochemistry, 1996, Jun-01, Volume: 238, Issue:2 Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Antibodies; Carcinogens; Corticosterone; Enzyme Inhibitors; Female; Glycyrrhetinic Acid; Hydroxysteroid Dehydrogenases; Kinetics; Liver; Mice; Mice, Inbred Strains; Molecular Structure; Nicotiana; Nitrosamines; Oxidation-Reduction; Oxidoreductases; Plants, Toxic	1996
Evidence for endogenous formation of tobacco-specific nitrosamines in rats treated with tobacco alkaloids and sodium nitrite. Carcinogenesis, 1997, Volume: 18, Issue:3 Topics: Alkaloids; Animals; Biotransformation; Drug Synergism; Glucuronates; Male; Nicotiana; Nicotine; Nitrosamines; Plant Extracts; Plants, Toxic; Rats; Rats, Inbred F344; Sodium Nitrite	1997
Differences in the urinary metabolites of the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in black and white smokers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1997, Volume: 6, Issue:10 Topics: Adult; Analysis of Variance; Animals; Biomarkers; Black People; Carcinogens; Cotinine; Creatinine; Female; Glucuronates; Humans; Incidence; Lung Neoplasms; Male; Menthol; Middle Aged; Nicotiana; Nitrosamines; Plants, Toxic; Rats; Smoking; White People	1997
Quantitation of urinary metabolites of a tobacco-specific lung carcinogen after smoking cessation. Cancer research, 1999, Feb-01, Volume: 59, Issue:3 Topics: Adult; Animals; Carcinogens; Cotinine; Female; Glucuronates; Humans; Lung Neoplasms; Male; Middle Aged; Nicotine; Nitrosamines; Rats; Rats, Inbred F344; Smoking Cessation	1999
Stereochemistry of metabolites of a tobacco-specific lung carcinogen in smokers' urine. Cancer research, 1999, Aug-01, Volume: 59, Issue:15 Topics: Carcinogens; Chromatography, Gas; Chromatography, Liquid; Glucuronates; Humans; Mass Spectrometry; Nicotiana; Nitrosamines; Plants, Toxic; Smoke; Smoking; Stereoisomerism	1999
Carbonyl reduction of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in cytosol of mouse liver and lung. Toxicology, 1999, Nov-29, Volume: 139, Issue:1-2 Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenases; Animals; Carcinogens; Chromatography, High Pressure Liquid; Cytosol; Female; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Liver; Lung; Male; Mice; Nicotiana; Nitrosamines; Oxidation-Reduction; Plants, Toxic; Reverse Transcriptase Polymerase Chain Reaction; Subcellular Fractions	1999