4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol

4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone has been researched along with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol in 83 studies

Research

Studies (83)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	10 (12.05)	18.2507
2000's	33 (39.76)	29.6817
2010's	39 (46.99)	24.3611
2020's	1 (1.20)	2.80

Authors

Authors	Studies
Hecht, SS	2
Akerkar, SA; Carmella, SG; Hecht, SS; Richie, JP	1
Collazo, NR; Sultatos, LG	1
Akerkar, SA; Borukhova, A; Carmella, SG; Chung, FL; Hecht, SS; Richie, JP; Skowronski, L	1
Atawodi, SE; Richter, E	1
Amin, S; Guengerich, FP; Hecht, SS; Koehl, W; Koenig, LA; Murphy, SE; Nunes, MG; Patten, CJ; Staretz, ME	1
Hecht, SS; Koenig, LA; Staretz, ME	1
Hecht, SS; Spratt, TE; Trushin, N	1
Carmella, SG; Chen, M; Hecht, SS; Lackmann, GM; Salzberger, U; Töllner, U	1
Castonguay, A; Donnelly, PJ; Massey, TE; Petsikas, D; Reid, KR; Smith, GB	1
Engl, J; Friesenegger, S; Richter, E; Tricker, AR	2
Carmella, SG; Guengerich, FP; Hecht, SS; Upadhyaya, P	1
Hecht, SS; McIntee, EJ; Upadhyaya, P	1
Carmella, SG; Hecht, SS; Upadhyaya, P; Wu, Z; Zimmerman, CL	1
Carmella, SG; Hatsukami, DK; Hecht, SS; Jensen, JA; Le, KA; Ye, M; Zimmerman, CL	1
Bissonnette, EY; Castonguay, A; Proulx, LI; Therriault, MJ	1
Ding, X; Jalas, JR; Murphy, SE	1
Carmella, SG; Hatsukami, DK; Hecht, SS; Jensen, J; Kramarczuk, I; Le, C; Li, YS; Losey, L; Murphy, SE; Puumala, SS; Roe, MR; Zimmerman, CL	1
Dossett, N; Fang, JL; Lazarus, P; Wiener, D	1
Hecht, SS; Upadhyaya, P; Wu, Z; Zimmerman, CL	1
Adgate, JL; Carmella, SG; Church, TR; Fredrickson, AL; Geisser, MS; Greaves, IA; Hecht, SS; Ramachandran, G; Ryan, AD; Sexton, K	1
Breyer-Pfaff, U; Ernst, M; Martin, HJ; Maser, E	1
Hecht, SS; Jalas, JR; Murphy, SE	1
Colosimo, S; Djordjevic, MV; Muscat, JE; Richie, JP; Stellman, SD	1
Carmella, SG; Hatsukami, DK; Hecht, SS; Lemmonds, C; Murphy, S; Tulunay, OE; Zhang, Y	1
Carmella, SG; Han, S; Hecht, SS; Villalta, PW	1
Carmella, SG; Hatsukami, DK; Hecht, SS; Joseph, AM; Le, CT; Mooney, ME; Zhang, Y	1
Hecht, SS; Kassie, F; Lao, Y; Villalta, PW; Yu, N	1
Carmella, SG; Hatsukami, DK; Hecht, SS; Le, C; Luo, X; Mooney, M; Murphy, SE; Riley, WT	1
Behr, M; Ding, X; Fang, C; Kaminsky, LS; Turesky, RJ; Weng, Y	1
Bedard, LL; Brown, PJ; Massey, TE; Petsikas, D; Reid, KR	1
Cheng, G; Hecht, SS; Upadhyaya, P; Villalta, PW; Wang, M	1
Hecht, SS; Hochalter, JB; Kalscheuer, S; Upadhyaya, P; Villalta, PW	1
Carmella, SG; Derby, KS; Hatsukami, D; Hecht, SS; Le Marchand, L; Murphy, SE; Tiirikainen, M; Wang, H	1
Chang, LW; Chung, CJ; Hsieh, DP; Hsueh, YM; Lee, HL; Lin, P; Liou, SH; Pu, YS	1
Anderson, KE; Benoit, AR; Caporaso, NE; Carmella, SG; Church, TR; Geisser, MS; Hecht, SS; Le, CT; Zhang, Y	1
Hecht, SS; Stepanov, I	1
Hecht, SS; Lao, Y; Lindgren, BR; Upadhyaya, P; Villalta, PW; Wang, M; Zhang, S	1
Caberto, C; Carmella, S; Cuthrell, K; Derby, KS; Hecht, SS; Le Marchand, L; Murphy, SE	1
Gregg, EO; Lowe, FJ; McEwan, M	1
Cheung, F; Errington, G; Kavvadias, D; McEwan, M; Scherer, G; Shepperd, J	1
Hecht, SS; Maertens, LA; Upadhyaya, P; Zimmerman, CL	1
Ashley, DL; Bernert, JT; Cummings, KM; Fong, GT; Giovino, GA; Hammond, D; Hatsukami, DK; Jain, RB; King, B; McCraw, JM; McNeill, A; O'Connor, RJ; Polzin, GM; Shahab, L; Watson, CH; Xia, Y; Yan, X; Zhang, L	1
Benowitz, N; Eisner, MD; Goniewicz, ML; Havel, C; Jacob, P; Koszowski, B; Lazcano-Ponce, E; Sobczak, A; Zielinska-Danch, W	1
Bernert, JT; Xia, Y	1
Carmella, SG; Hatsukami, DK; Hecht, SS; Hertsgaard, LA; Jensen, JA; Kotlyar, M; Lindgren, BR; Murphy, SE; Stepanov, I	1
Ashley, DL; Bernert, JT; Jain, RB; Pirkle, JL; Xia, Y	1
Bhat, SH; Blair, IA; Gelhaus, SL; Mesaros, C; Vachani, A	1
Liang, Q; Mendes, P; Sarkar, M; Wang, J	1
Chung, CJ; Hsueh, YM; Lee, HL; Lin, P; Pu, YS; Shiue, HS; Su, CT; Yang, HY	1
Ahluwalia, JS; An, LC; Balbo, S; Carmella, SG; Davis, A; Guo, H; Han, S; Hecht, SS; Murphy, SE; Thomas, JL; Yoder, A	1
Asomaning, K; Carmella, SG; Chen, F; Christiani, DC; Hecht, SS; Lin, X; Su, L; Ter-Minassian, M; Zhao, Y	1
Bai, Y; Li, N; Liao, J; Liu, H; Nie, H; Pang, N; Yang, Y; Yu, C; Zhou, M	1
Carmella, SG; Chen, M; Davis, AB; Gao, YT; Han, S; Hecht, SS; Moy, KA; Murphy, SE; Nelson, HH; Tao, L; Wang, R; Yu, MC; Yuan, JM; Zhong, Y	1
Hou, H; Hu, Q; Liu, Y; Tang, G; Tian, Y; Zhang, X	1
Chen, JS; Lee, HL; Li, MH; Wu, JP	1
Batra, SK; Kaur, S; Kumar, S; Momi, N; Ponnusamy, MP; Wittel, UA	1
Chung, CJ; Hsueh, YM; Huang, CY; Lee, HL; Lin, P; Pu, YS; Su, CT; Wu, CC	1
Liang, Q; Sarkar, M; Wang, J	1
Cao, B; Lang, H; Mao, J; Wang, J; Wang, L; Wang, S; Zhang, J; Zhang, Q; Zhao, B	1
Skarydova, L; Stambergova, H; Wsol, V; Zverinova, M	1
Ding, X; Liu, Z; Megaraj, V; Xie, F; Yang, W; Zhou, X	1
Chao, MR; Chen, JL; Hsu, YW; Hu, CW; Tam, LM	1
Butler, LM; Hecht, SS; Stepanov, I; Yuan, JM	1
Benowitz, NL; Carmella, SG; Chatfield, DA; Chen, M; Daffa, RM; Hecht, SS; Hovell, MF; Jackson, SR; Jacob, P; Kassem, NO; Liles, S; Matt, GE; Mehta, S; Younis, MA	1
Cao, B; Feng, M; Ji, H; Lang, H; Liu, J; Zhang, J; Zhang, Q	1
Printz, C	1
Balbo, S; Hecht, SS; James-Yi, SA; Johnson, CS; Khariwala, SS; Kovi, RC; Le, CT; O'Sullivan, MG; Upadhyaya, P; Wang, M	1
Chen, B; Hu, B; Li, XF; Qian, Y; Wu, M; Zhu, L	1
Hwang, SH; Jeong, BY; Lee, DH; Lim, MK; Park, EY; Yang, W; Yun, EH	1
Ansari, MY; Dhasmana, A; Firdaus, S; Haque, S; Jamal, QM; Lohani, M; Sahoo, GC	1
Chen, G; Kozlovich, S; Lazarus, P	1
Benowitz, NL; Hoh, E; Hovell, MF; Jacob, P; Khan, AM; Matt, GE; Northrup, TF; Stotts, AL	1
Chen, G; Kozlovich, S; Lazarus, P; Luo, S	1
Ahmed, MS; Fokina, VM; Hankins, GDV; Nanovskaya, T; Oncken, C; Patrikeeva, SL	1
Maser, E; Neumann, KT; Stapelfeld, C	1
Carlson, ES; Hecht, SS; Ma, B; Stepanov, I; Upadhyaya, P; Villalta, PW; Zarth, AT	1
Balbo, S; Hecht, SS; Johnson, CS; Kovi, RC; O'Sullivan, MG	1
Ashmore, JH; Lazarus, P; Luo, S; Watson, CJW	1
Bryant, M; Cao, X; Fu, X; Guo, L; Qin, Q; Rosenfeldt, H; Wang, Y; Wu, Q; Xiong, R	1
Lee, DH; Lee, TS; Oh, JE; Park, MB	1

Reviews

5 review(s) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol

Article	Year
Chemoprevention by isothiocyanates. Journal of cellular biochemistry. Supplement, 1995, Volume: 22 Topics: Animals; Anticarcinogenic Agents; Biotransformation; Carcinogens; Humans; Inactivation, Metabolic; Isothiocyanates; Lung Neoplasms; Mice; Nitrosamines; Rats	1995
Carcinogen derived biomarkers: applications in studies of human exposure to secondhand tobacco smoke. Tobacco control, 2004, Volume: 13 Suppl 1 Topics: Air Pollutants; Benzene; Biomarkers, Tumor; Carcinogens; Environmental Exposure; Female; Humans; Hydrocarbons, Aromatic; Lung Neoplasms; Male; Nitrosamines; Pyridines; Risk Factors; Tobacco Smoke Pollution	2004
Cytochrome P450 enzymes as catalysts of metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco specific carcinogen. Chemical research in toxicology, 2005, Volume: 18, Issue:2 Topics: Animals; Carcinogens; Catalysis; Cytochrome P-450 Enzyme System; Humans; Microsomes; Nicotiana; Nitrosamines; Pyridines; Species Specificity	2005
Interplay between smoking-induced genotoxicity and altered signaling in pancreatic carcinogenesis. Carcinogenesis, 2012, Volume: 33, Issue:9 Topics: Humans; Inflammation; Mutation; Nitrosamines; Pancreatic Neoplasms; Polymorphism, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Pyridines; ras Proteins; Receptors, Nicotinic; Signal Transduction; Smoking	2012
Urinary tobacco smoke-constituent biomarkers for assessing risk of lung cancer. Cancer research, 2014, Jan-15, Volume: 74, Issue:2 Topics: Biomarkers; Carcinogens; Cotinine; Glucuronides; Humans; Lung Neoplasms; Mass Spectrometry; Multivariate Analysis; Nicotiana; Nicotine; Nitrosamines; Phenanthrenes; Polycyclic Aromatic Hydrocarbons; Prospective Studies; Pyridines; Risk; Risk Assessment; Smoke	2014

Trials

4 trial(s) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol

Article	Year
Effects of reduced cigarette smoking on the uptake of a tobacco-specific lung carcinogen. Journal of the National Cancer Institute, 2004, Jan-21, Volume: 96, Issue:2 Topics: Adult; Aged; Alkaloids; Biomarkers, Tumor; Carcinogens; Cotinine; Female; Glucuronates; Humans; Lung Neoplasms; Male; Middle Aged; Nitrosamines; Pyridines; Research Design; Smoking; Smoking Cessation; Treatment Outcome	2004
Similar exposure to a tobacco-specific carcinogen in smokeless tobacco users and cigarette smokers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2007, Volume: 16, Issue:8 Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers; Carcinogens; Cotinine; Creatinine; Female; Humans; Male; Middle Aged; Nitrosamines; Pyridines; Sex Factors; Smoking; Smoking Cessation; Tobacco Use Cessation; Tobacco, Smokeless	2007
Effect of oral snus and medicinal nicotine in smokers on toxicant exposure and withdrawal symptoms: a feasibility study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2011, Volume: 20, Issue:1 Topics: Adolescent; Adult; Aged; Carbon Monoxide; Cotinine; Feasibility Studies; Humans; Middle Aged; Nicotine; Nitrosamines; Pyridines; Smoking; Smoking Cessation; Substance Withdrawal Syndrome; Tobacco, Smokeless; Young Adult	2011
Metabolites of a tobacco-specific lung carcinogen in children exposed to secondhand or thirdhand tobacco smoke in their homes. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2011, Volume: 20, Issue:6 Topics: Adult; Biomarkers; Carcinogens; Cells, Cultured; Child; Child, Preschool; Environmental Monitoring; Female; Hepatocytes; Humans; Infant; Infant, Newborn; Lung; Male; Nitrosamines; Pyridines; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tobacco Smoke Pollution	2011

Other Studies

74 other study(ies) available for 4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol

Article	Year
Intraindividual and interindividual differences in metabolites of the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in smokers' urine. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1995, Volume: 4, Issue:6 Topics: Adult; Aged; Analysis of Variance; Carcinogens; Cotinine; Creatinine; Female; Gas Chromatography-Mass Spectrometry; Glucuronates; Humans; Male; Middle Aged; Nitrosamines; Radioimmunoassay; Smoking	1995
Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human placental microsomes. Biochemical pharmacology, 1995, Nov-27, Volume: 50, Issue:11 Topics: Alcohol Oxidoreductases; Carcinogens; Computer Simulation; Cytochrome P-450 Enzyme System; Humans; Kinetics; Lung; Microsomes; Microsomes, Liver; NAD; NADP; Nitrosamines; Placenta	1995
Effects of watercress consumption on metabolism of a tobacco-specific lung carcinogen in smokers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1995, Volume: 4, Issue:8 Topics: Adult; Anticarcinogenic Agents; Carcinogens; Female; Follow-Up Studies; Glucuronates; Humans; Isothiocyanates; Lung Neoplasms; Male; Nitrosamines; Prognosis; Smoking; Vegetables	1995
Bacterial reduction of N-oxides of tobacco-specific nitrosamines (TSNA). Human & experimental toxicology, 1996, Volume: 15, Issue:4 Topics: Animals; Bacteria; Carcinogens; Humans; Hydrogen-Ion Concentration; Nitrosamines; Rats; Smoking; Urinary Tract Infections	1996
Comparative metabolism of the tobacco-related carcinogens benzo[a]pyrene, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and N'- nitrosonornicotine in human hepatic microsomes. Drug metabolism and disposition: the biological fate of chemicals, 1997, Volume: 25, Issue:2 Topics: Benzo(a)pyrene; Biotransformation; Carcinogens; Cytochrome P-450 Enzyme System; Humans; Microsomes, Liver; Nicotiana; Nitrosamines; Plants, Toxic	1997
Effects of long term dietary phenethyl isothiocyanate on the microsomal metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F344 rats. Carcinogenesis, 1997, Volume: 18, Issue:9 Topics: Animals; Anticarcinogenic Agents; Diet; Glucuronates; Isothiocyanates; Lung; Male; Microsomes; Microsomes, Liver; Nitrosamines; Rats; Rats, Inbred F344	1997
Absolute configuration of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol formed metabolically from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Carcinogenesis, 1997, Volume: 18, Issue:9 Topics: Animals; Microsomes, Liver; Molecular Conformation; Nitrosamines; Rats; Stereoisomerism	1997
Metabolites of a tobacco-specific carcinogen in urine from newborns. Journal of the National Cancer Institute, 1999, Mar-03, Volume: 91, Issue:5 Topics: Adult; Carcinogens; Cotinine; Female; Gas Chromatography-Mass Spectrometry; Glucuronates; Humans; Infant, Newborn; Nicotine; Nitrosamines; Pregnancy; Prenatal Exposure Delayed Effects; Smoking	1999
Biotransformation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in freshly isolated human lung cells. Carcinogenesis, 1999, Volume: 20, Issue:9 Topics: Aged; Biotransformation; Carcinogens; Female; Humans; Hydroxylation; Inactivation, Metabolic; Lung; Lung Neoplasms; Macrophages, Alveolar; Male; Middle Aged; Nitrosamines; Oxidation-Reduction; Proadifen; Pulmonary Alveoli	1999
Use of precision-cut tissue slices in organ culture to study metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by hamster lung, liver and kidney. Toxicology, 2000, Apr-03, Volume: 144, Issue:1-3 Topics: Animals; Carcinogens; Chromatography, High Pressure Liquid; Cricetinae; Female; Kidney; Kinetics; L-Lactate Dehydrogenase; Liver; Lung; Mesocricetus; Microtomy; Nitrosamines; Organ Culture Techniques; Potassium	2000
Formation and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol enantiomers in vitro in mouse, rat and human tissues. Carcinogenesis, 2000, Volume: 21, Issue:6 Topics: Animals; Chromatography, High Pressure Liquid; Female; Humans; Male; Mice; Nitrosamines; Rats; Rats, Inbred F344; Stereoisomerism	2000
Preparation of pyridine-N-glucuronides of tobacco-specific nitrosamines. Chemical research in toxicology, 2001, Volume: 14, Issue:5 Topics: Chromatography, High Pressure Liquid; Glucuronides; Magnetic Resonance Spectroscopy; Nicotiana; Nitrosamines; Plants, Toxic; Pyridines	2001
Disposition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in bile duct-cannulated rats: stereoselective metabolism and tissue distribution. Carcinogenesis, 2002, Volume: 23, Issue:1 Topics: Animals; Bile; Bile Ducts; Catheterization; Chromatography, Gas; Chromatography, High Pressure Liquid; Differential Thermal Analysis; Half-Life; Kidney; Liver; Lung; Male; Nitrosamines; Organ Specificity; Radioisotopes; Rats; Rats, Inbred F344; Stereoisomerism	2002
Quantitation of metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone after cessation of smokeless tobacco use. Cancer research, 2002, Jan-01, Volume: 62, Issue:1 Topics: Administration, Oral; Adult; Glucuronates; Humans; Male; Middle Aged; Nitrosamines; Tobacco Use Cessation; Tobacco, Smokeless	2002
Immunomodulatory effects of the tobacco-specific carcinogen, NNK, on alveolar macrophages. Clinical and experimental immunology, 2003, Volume: 132, Issue:2 Topics: Animals; Antibodies, Monoclonal; Carcinogens; Cell Line; Chemokine CCL3; Chemokine CCL4; Cyclooxygenase Inhibitors; Depression, Chemical; Dinoprostone; Dose-Response Relationship, Drug; Indomethacin; Interleukin-10; Interleukin-12; Lipopolysaccharides; Macrophage Inflammatory Proteins; Macrophages, Alveolar; Nitric Oxide; Nitrobenzenes; Nitrosamines; Pyridines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Smoking; Sulfonamides; Time Factors; Tumor Necrosis Factor-alpha	2003
Comparative metabolism of the tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol by rat cytochrome P450 2A3 and human cytochrome P450 2A13. Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:10 Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2A6; Humans; Mixed Function Oxygenases; Nicotiana; Nitrosamines; Pyridines; Rats; Spodoptera	2003
Correlation between UDP-glucuronosyltransferase genotypes and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone glucuronidation phenotype in human liver microsomes. Cancer research, 2004, Feb-01, Volume: 64, Issue:3 Topics: Codon; Genotype; Glucuronates; Glucuronosyltransferase; Humans; Inactivation, Metabolic; Microsomes, Liver; Nitrosamines; Polymorphism, Genetic; Pyridines	2004
Stereoselective metabolism and tissue retention in rats of the individual enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), metabolites of the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Carcinogenesis, 2004, Volume: 25, Issue:7 Topics: Animals; Male; Nitrosamines; Organ Specificity; Pyridines; Rats; Rats, Inbred F344; Time Factors	2004
Children's exposure to environmental tobacco smoke: using diverse exposure metrics to document ethnic/racial differences. Environmental health perspectives, 2004, Volume: 112, Issue:3 Topics: Biomarkers; Caregivers; Child; Cotinine; Data Collection; Epidemiologic Studies; Ethnicity; Female; Glucuronates; Humans; Male; Nitrosamines; Poverty; Pyridines; Racial Groups; Reproducibility of Results; Surveys and Questionnaires; Tobacco Smoke Pollution	2004
Enantioselectivity of carbonyl reduction of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone by tissue fractions from human and rat and by enzymes isolated from human liver. Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:9 Topics: 11-beta-Hydroxysteroid Dehydrogenases; 20-Hydroxysteroid Dehydrogenases; Alcohol Oxidoreductases; Aldehyde Reductase; Animals; Chromatography, High Pressure Liquid; Cytosol; Female; Glycyrrhetinic Acid; Humans; Hydroxysteroid Dehydrogenases; Lung; Male; Microsomes, Liver; Nitrosamines; Oxidoreductases; Placenta; Pyridines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Stereoisomerism	2004
Racial differences in exposure and glucuronidation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Cancer, 2005, Apr-01, Volume: 103, Issue:7 Topics: Adult; Black People; Carcinogens; Cotinine; Female; Glucuronates; Humans; Male; Middle Aged; Nitrosamines; Pyridines; Racial Groups; Smoking; Thiocyanates; Tobacco Smoke Pollution; White People	2005
Urinary metabolites of a tobacco-specific lung carcinogen in nonsmoking hospitality workers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2005, Volume: 14, Issue:5 Topics: Adolescent; Adult; Air Pollutants, Occupational; Biomarkers; Carcinogens; Cotinine; Creatinine; Female; Glucuronates; Humans; Interviews as Topic; Lung Neoplasms; Male; Middle Aged; Nicotine; Nitrosamines; Pyridines; Restaurants; Tobacco Smoke Pollution; Workforce	2005
Analysis of total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in smokers' blood. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2005, Volume: 14, Issue:11 Pt 1 Topics: Biomarkers; Carcinogens; Chromatography, Liquid; Humans; Mass Spectrometry; Nitrosamines; Pyridines; Sensitivity and Specificity; Smoking	2005
Toxicant exposure in cigarette reducers versus light smokers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2006, Volume: 15, Issue:12 Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Chewing Gum; Environmental Exposure; Female; Humans; Male; Middle Aged; Nicotine; Nitrosamines; Pyridines; Smoking; Smoking Cessation	2006
Formation and accumulation of pyridyloxobutyl DNA adducts in F344 rats chronically treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol. Chemical research in toxicology, 2007, Volume: 20, Issue:2 Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; DNA Adducts; Dose-Response Relationship, Drug; Lung Neoplasms; Male; Molecular Structure; Nitrosamines; Organ Specificity; Pyridines; Rats; Rats, Inbred F344; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Time Factors	2007
Determination of the role of target tissue metabolism in lung carcinogenesis using conditional cytochrome P450 reductase-null mice. Cancer research, 2007, Aug-15, Volume: 67, Issue:16 Topics: Animals; Carcinogens; Doxycycline; Female; Guanine; Inbreeding; Liver; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Mice, Transgenic; NADPH-Ferrihemoprotein Reductase; Nitrosamines; Pyridines	2007
Analysis of CYP2A contributions to metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human peripheral lung microsomes. Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:11 Topics: Aged; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP2A6; Female; Gene Expression; Genotype; Glycols; Humans; Hydroxy Acids; Hydroxylation; Keto Acids; Lung; Male; Microsomes; Middle Aged; Mixed Function Oxygenases; Molecular Structure; Nitrosamines; Oxidation-Reduction; Polymorphism, Single Nucleotide; Pyridines; Smoking; Steroid Hydroxylases	2007
Formation of formaldehyde adducts in the reactions of DNA and deoxyribonucleosides with alpha-acetates of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), and N-nitrosodimethylamine (NDMA). Chemical research in toxicology, 2008, Volume: 21, Issue:3 Topics: Acetates; Carcinogens; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Deoxyribonucleosides; Dimethylnitrosamine; DNA Adducts; Formaldehyde; Nitrosamines; Pyridines; Spectrometry, Mass, Electrospray Ionization	2008
Quantitation of pyridylhydroxybutyl-DNA adducts in liver and lung of F-344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol. Chemical research in toxicology, 2008, Volume: 21, Issue:7 Topics: Animals; Carcinogens; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Liver; Lung; Magnetic Resonance Spectroscopy; Male; Nitrosamines; Prohibitins; Pyridines; Rats; Rats, Inbred F344; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Tandem Mass Spectrometry	2008
Smokers with the CHRNA lung cancer-associated variants are exposed to higher levels of nicotine equivalents and a carcinogenic tobacco-specific nitrosamine. Cancer research, 2008, Nov-15, Volume: 68, Issue:22 Topics: Adult; Aged; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nerve Tissue Proteins; Nicotine; Nitrosamines; Polymorphism, Single Nucleotide; Pyridines; Receptors, Nicotinic; Smoking	2008
Correlation between the urine profile of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolites and N7-methylguanine in urothelial carcinoma patients. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:12 Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Carcinogens; Female; Guanine; Humans; Male; Middle Aged; Nitrosamines; Pyridines; Smoking; Surveys and Questionnaires; Urinary Bladder Neoplasms	2008
A prospectively measured serum biomarker for a tobacco-specific carcinogen and lung cancer in smokers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009, Volume: 18, Issue:1 Topics: Aged; Biomarkers, Tumor; Case-Control Studies; Chi-Square Distribution; Female; Glucuronates; Humans; Logistic Models; Lung Neoplasms; Male; Middle Aged; Nicotiana; Nitrosamines; Prospective Studies; Pyridines; Risk Factors	2009
Mitochondrial DNA adducts in the lung and liver of F344 rats chronically treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and (S)-4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol. Chemical research in toxicology, 2009, Volume: 22, Issue:2 Topics: Animals; Carcinogenicity Tests; Carcinogens; Chromatography, High Pressure Liquid; DNA Adducts; DNA, Mitochondrial; Liver; Lung; Nitrosamines; Prohibitins; Pyridines; Rats; Rats, Inbred F344; Smoking; Spectrometry, Mass, Electrospray Ionization	2009
Analysis of pyridyloxobutyl and pyridylhydroxybutyl DNA adducts in extrahepatic tissues of F344 rats treated chronically with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol. Chemical research in toxicology, 2009, Volume: 22, Issue:5 Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; DNA Adducts; Male; Nitrosamines; Organ Specificity; Prohibitins; Pyridines; Rats; Rats, Inbred F344; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism	2009
Biotransformation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in lung tissue from mouse, rat, hamster, and man. Chemical research in toxicology, 2009, Volume: 22, Issue:6 Topics: Aged; Animals; Biotransformation; Carcinogens; Cells, Cultured; Cricetinae; DNA Methylation; Female; Humans; Kinetics; Lung; Male; Mice; Middle Aged; Nitrosamines; Pyridines; Rats; Smoking	2009
Exposure to the carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in smokers from 3 populations with different risks of lung cancer. International journal of cancer, 2009, Nov-15, Volume: 125, Issue:10 Topics: Aged; Asian; Carcinogens; Cross-Sectional Studies; Ethnicity; Female; Follow-Up Studies; Glucuronates; Hawaii; Humans; Inactivation, Metabolic; Lung Neoplasms; Male; Middle Aged; Nicotine; Nitrosamines; Prognosis; Pyridines; Risk Factors; Smoking; Survival Rate; White People	2009
Evaluation of biomarkers of exposure and potential harm in smokers, former smokers and never-smokers. Clinical chemistry and laboratory medicine, 2009, Volume: 47, Issue:3 Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Biomarkers; Cholesterol, LDL; Cross-Sectional Studies; Deoxyguanosine; Dinoprost; Female; Humans; Immunoglobulin G; Male; Middle Aged; Nicotine; Nitrosamines; Pyridines; Reproducibility of Results; Smoke; Smoking; Smoking Cessation; Thromboxane B2; Thymidine	2009
Determination of tobacco-specific N-nitrosamines in urine of smokers and non-smokers. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 2009, Volume: 14, Issue:8 Topics: Carcinogens; Humans; Nicotiana; Nitrosamines; Pyridines; Smoke; Smoking	2009
Formation and distribution of NNK metabolites in an isolated perfused rat lung. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:5 Topics: Animals; Cyclic N-Oxides; DNA Adducts; Enzyme Inhibitors; Isothiocyanates; Keto Acids; Lung; Male; Metabolism; Nitrosamines; Perfusion; Pyridines; Rats; Rats, Inbred F344	2010
Effect of differing levels of tobacco-specific nitrosamines in cigarette smoke on the levels of biomarkers in smokers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2010, Volume: 19, Issue:6 Topics: Adolescent; Adult; Biomarkers; Cotinine; Female; Humans; Male; Middle Aged; Nicotiana; Nicotine; Nitrosamines; Pyridines; Saliva; Smoking; Young Adult	2010
Urine cotinine underestimates exposure to the tobacco-derived lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in passive compared with active smokers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2010, Volume: 19, Issue:11 Topics: Adult; Biomarkers; Carcinogens; Chromatography, Liquid; Cotinine; Female; Humans; Male; Middle Aged; Nitrosamines; Pyridines; Smoking; Tandem Mass Spectrometry; Tobacco Smoke Pollution	2010
Stability of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in urine samples stored at various temperatures. Journal of analytical toxicology, 2010, Volume: 34, Issue:7 Topics: Biomarkers; Glucuronides; Humans; Nicotiana; Nitrosamines; Pyridines; Specimen Handling; Temperature; Time Factors	2010
Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in smokers in the United States: NHANES 2007-2008. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 2011, Volume: 16, Issue:2 Topics: Adolescent; Adult; Aged; Biomarkers; Black People; Carcinogens; Cotinine; Creatinine; Female; Humans; Male; Middle Aged; Nicotiana; Nicotine; Nitrosamines; Nutrition Surveys; Pyridines; Smoking; Tars; United States; White People; Young Adult	2011
A new liquid chromatography/mass spectrometry method for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in urine. Rapid communications in mass spectrometry : RCM, 2011, Jan-15, Volume: 25, Issue:1 Topics: Biomarkers, Tumor; Case-Control Studies; Chromatography, Liquid; Creatinine; DNA Adducts; Drug Stability; Humans; Isotope Labeling; Lung Neoplasms; Mass Spectrometry; Nitrosamines; Phenotype; Pyridines; Reproducibility of Results; Risk Factors; Sensitivity and Specificity; Smoking	2011
Is 24h nicotine equivalents a surrogate for smoke exposure based on its relationship with other biomarkers of exposure? Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 2011, Volume: 16, Issue:2 Topics: Acrolein; Adult; Benzene; Biomarkers; Butadienes; Carbon Monoxide; Environmental Exposure; Female; Humans; Male; Nicotiana; Nicotine; Nitrosamines; Pyrenes; Pyridines; Randomized Controlled Trials as Topic; Smoke; Smoking; Time Factors	2011
Low ratio of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol-glucuronides (NNAL-Gluc)/free NNAL increases urothelial carcinoma risk. The Science of the total environment, 2011, Apr-01, Volume: 409, Issue:9 Topics: Biomarkers; Carcinoma; Case-Control Studies; Female; Glucuronides; Humans; Male; Middle Aged; Nitrosamines; Pyridines; Risk Factors; Smoking; Urologic Neoplasms	2011
Genetic variability in the metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL). International journal of cancer, 2012, Mar-15, Volume: 130, Issue:6 Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adult; Aged; Case-Control Studies; Creatinine; Female; Humans; Individuality; Lung Neoplasms; Male; Middle Aged; Nicotine; Nitrosamines; Oxidoreductases; Polymorphism, Single Nucleotide; Pyridines; Smoking; Tobacco Smoke Pollution	2012
Metabolic study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone to the enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in vitro in human bronchial epithelial cells using chiral capillary electrophoresis. Journal of chromatography. A, 2011, Sep-16, Volume: 1218, Issue:37 Topics: Bronchi; Cells, Cultured; Electrophoresis, Capillary; Epithelial Cells; Humans; Nitrosamines; Pyridines; Reproducibility of Results; Respiratory Mucosa; Sensitivity and Specificity; Solid Phase Extraction; Stereoisomerism	2011
Urinary levels of cigarette smoke constituent metabolites are prospectively associated with lung cancer development in smokers. Cancer research, 2011, Nov-01, Volume: 71, Issue:21 Topics: Aged; China; Cotinine; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nicotiana; Nicotine; Nitrosamines; Phenanthrenes; Prospective Studies; Pyridines; Smoke; Smoking	2011
Development of a method for the determination of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in urine of nonsmokers and smokers using liquid chromatography/tandem mass spectrometry. Journal of pharmaceutical and biomedical analysis, 2012, Apr-07, Volume: 63 Topics: Biomarkers; Biotransformation; Carcinogens; Case-Control Studies; China; Chromatography, Liquid; Humans; Limit of Detection; Nitrosamines; Pyridines; Reproducibility of Results; Risk Assessment; Smoking; Tandem Mass Spectrometry; Tars; Time Factors	2012
In vivo and in vitro metabolism of tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), by the freshwater planarian, Dugesia japonica. Chemosphere, 2012, Volume: 87, Issue:11 Topics: Alcohol Oxidoreductases; Animals; Models, Animal; Nicotiana; Nitrosamines; Planarians; Pyridines; Water Pollutants, Chemical	2012
Joint effect of arsenic methylation profile and NNK metabolites on urothelial carcinoma. The Journal of urology, 2012, Volume: 188, Issue:5 Topics: Arsenic; Carcinoma, Transitional Cell; Case-Control Studies; Humans; Methylation; Nitrosamines; Pyridines; Risk; Smoking; Urologic Neoplasms	2012
Metabolism of nicotine and 4-(methylnitrosamino)-l-(3-pyridyl)-lbutanone (NNK) in menthol and non-menthol cigarette smokers. Drug metabolism letters, 2012, Sep-01, Volume: 6, Issue:3 Topics: Adult; Black or African American; Cotinine; Cross-Sectional Studies; Female; Glucuronides; Humans; Male; Menthol; Middle Aged; Nicotine; Nitrosamines; Pyridines; Smoking; Tobacco Products; White People; Young Adult	2012
Simultaneous determination of NNK and its seven metabolites in rabbit blood by hydrophilic interaction liquid chromatography-tandem mass spectrometry. Analytical and bioanalytical chemistry, 2013, Volume: 405, Issue:6 Topics: Animals; Biotransformation; Carcinogens; Chromatography, Liquid; Cyclic N-Oxides; Hydrophobic and Hydrophilic Interactions; Hydroxylation; Limit of Detection; Male; Nitrosamines; Pyridines; Rabbits; Reproducibility of Results; Tandem Mass Spectrometry	2013
A simple identification of novel carbonyl reducing enzymes in the metabolism of the tobacco specific carcinogen NNK. Drug metabolism letters, 2012, Sep-01, Volume: 6, Issue:3 Topics: Alcohol Oxidoreductases; Carcinogens; Chromatography, High Pressure Liquid; Humans; Microsomes, Liver; Nitrosamines; Pyridines; Smoking; Stereoisomerism	2012
Role of CYP2A13 in the bioactivation and lung tumorigenicity of the tobacco-specific lung procarcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: in vivo studies using a CYP2A13-humanized mouse model. Carcinogenesis, 2014, Volume: 35, Issue:1 Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carcinogens; Cytochrome P-450 CYP2A6; Cytochrome P450 Family 2; DNA Adducts; Guanine; Humans; Lung Neoplasms; Mice, Transgenic; Microsomes; Nicotiana; Nitrosamines; Pyridines	2014
Direct analysis of tobacco-specific nitrosamine NNK and its metabolite NNAL in human urine by LC-MS/MS: evidence of linkage to methylated DNA lesions. Archives of toxicology, 2014, Volume: 88, Issue:2 Topics: Adenine; Adult; Biomarkers; Chromatography, Liquid; Cotinine; DNA Methylation; Guanine; Humans; Limit of Detection; Nicotine; Nitrosamines; Pyridines; Sensitivity and Specificity; Smoking; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry	2014
Children's exposure to secondhand and thirdhand smoke carcinogens and toxicants in homes of hookah smokers. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2014, Volume: 16, Issue:7 Topics: Acetylcysteine; Air; Biomarkers; Carcinogens; Child, Preschool; Cotinine; Cross-Sectional Studies; Environmental Exposure; Family Characteristics; Female; Housing; Humans; Male; Nicotine; Nitrosamines; Pyridines; Smoking; Tobacco Smoke Pollution	2014
Simultaneous determination of NNK and its metabolites in mouse tissue for evaluating the effects of chronic alcohol consumption on the metabolism of NNK in mouse liver and lung. Analytical and bioanalytical chemistry, 2014, Volume: 406, Issue:18 Topics: Alcoholism; Animals; Area Under Curve; Calibration; Chromatography, Liquid; Female; Hydroxylation; Limit of Detection; Liver; Lung; Mice, Inbred C57BL; Nitrosamines; Pyridines; Tandem Mass Spectrometry	2014
The impact of water pipe and tobacco marketing on young people. Cancer, 2014, Oct-01, Volume: 120, Issue:19 Topics: Adolescent; Adult; Carcinogens; Female; Humans; Male; Marketing; Nicotine; Nitrosamines; Pyridines; Smoking; Tobacco Products; Young Adult	2014
Carcinogenicity and DNA adduct formation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F-344 rats. Carcinogenesis, 2014, Volume: 35, Issue:12 Topics: Adenocarcinoma; Adenoma; Animals; Apoptosis; Carcinogens; Chromatography, High Pressure Liquid; DNA Adducts; DNA Damage; Humans; Lung Neoplasms; Male; Nitrosamines; Pancreatic Neoplasms; Prohibitins; Pyridines; Rats; Rats, Inbred F344; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism	2014
Identification of precursors and mechanisms of tobacco-specific nitrosamine formation in water during chloramination. Environmental science & technology, 2015, Jan-06, Volume: 49, Issue:1 Topics: Alkaloids; Chloramines; Chromatography, Liquid; Drinking Water; Halogenation; Mass Spectrometry; Nicotiana; Nicotine; Nitrosamines; Pyridines; Solid Phase Extraction; Tandem Mass Spectrometry; Water Pollutants, Chemical	2015
Consequences of Incomplete Smoke-Free Legislation in the Republic of Korea: Results from Environmental and Biochemical Monitoring: Community Based Study. Cancer research and treatment, 2016, Volume: 48, Issue:1 Topics: Air; Air Pollution, Indoor; Cotinine; Environmental Exposure; Environmental Monitoring; Hair; Humans; Nicotine; Nitrosamines; Particulate Matter; Private Facilities; Public Facilities; Republic of Korea; Schools; Tobacco Smoke Pollution; Toilet Facilities	2016
Binding Pattern Elucidation of NNK and NNAL Cigarette Smoke Carcinogens with NER Pathway Enzymes: an Onco- Informatics Study. Asian Pacific journal of cancer prevention : APJCP, 2015, Volume: 16, Issue:13 Topics: Algorithms; Calcium-Binding Proteins; Carcinogens; Cell Cycle Proteins; Chromatography, High Pressure Liquid; Computational Biology; Cyclin H; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Humans; Models, Molecular; Molecular Docking Simulation; Nitrosamines; Protein Interaction Domains and Motifs; Pyridines; Smoking	2015
Stereospecific Metabolism of the Tobacco-Specific Nitrosamine, NNAL. Chemical research in toxicology, 2015, Nov-16, Volume: 28, Issue:11 Topics: 20-Hydroxysteroid Dehydrogenases; Carcinogens; Escherichia coli; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Humans; Microsomes, Liver; Nicotiana; Nitrosamines; Pyridines; Stereoisomerism	2015
Thirdhand smoke contamination in hospital settings: assessing exposure risk for vulnerable paediatric patients. Tobacco control, 2016, Volume: 25, Issue:6 Topics: Carcinogens; Cotinine; Environmental Exposure; Environmental Monitoring; Female; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Nicotine; Nitrosamines; Pregnancy; Tobacco Smoke Pollution	2016
Association between Glucuronidation Genotypes and Urinary NNAL Metabolic Phenotypes in Smokers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2016, Volume: 25, Issue:7 Topics: Carcinogens; Genotype; Glucuronates; Glucuronides; Glucuronosyltransferase; Humans; Isomerism; Minor Histocompatibility Antigens; Neoplasms, Glandular and Epithelial; Nitrosamines; Polymorphism, Genetic; Pyridines; Smoking; Tobacco Products	2016
The Role of Placental Carbonyl Reducing Enzymes in Biotransformation of Bupropion and 4-methylnitrosamino-1-(3-pyridyl)-1-butanone. Drug metabolism letters, 2017, 11-17, Volume: 11, Issue:1 Topics: Antidepressive Agents; Biotransformation; Bupropion; Cigarette Smoking; Female; Humans; Microsomes; Nitrosamines; Placenta; Pregnancy; Subcellular Fractions; Trophoblasts	2017
Different inhibitory potential of sex hormones on NNK detoxification in vitro: A possible explanation for gender-specific lung cancer risk. Cancer letters, 2017, 10-01, Volume: 405 Topics: Carcinogens; Female; Gonadal Steroid Hormones; Humans; Liver; Lung Neoplasms; Male; Nicotiana; Nitrosamines; Pyridines; Sex Factors; Smoking; Tumor Cells, Cultured	2017
Methyl DNA Phosphate Adduct Formation in Rats Treated Chronically with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of Its Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol. Chemical research in toxicology, 2018, 01-16, Volume: 31, Issue:1 Topics: Animals; DNA Adducts; DNA Methylation; Hydrolysis; Lung; Male; Molecular Structure; Nitrosamines; Phosphates; Rats; Rats, Inbred F344; Stereoisomerism	2018
Metastasis to the F344 Rat Pancreas from Lung Cancer Induced by 4-(Methylnitrosamino)- 1-(3-pyridyl)-1-butanone and Enantiomers of Its Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)- 1-butanol, Constituents of Tobacco Products. Toxicologic pathology, 2018, Volume: 46, Issue:2 Topics: Animals; Carcinogens; Carcinoma; Lung Neoplasms; Male; Nicotiana; Nitrosamines; Pancreatic Neoplasms; Rats; Rats, Inbred F344; Stereoisomerism	2018
Carbonyl reduction of NNK by recombinant human lung enzymes: identification of HSD17β12 as the reductase important in (R)-NNAL formation in human lung. Carcinogenesis, 2018, 07-30, Volume: 39, Issue:8 Topics: 17-Hydroxysteroid Dehydrogenases; Carcinogenesis; Carcinogens; Cytosol; Enzyme Assays; Gene Knockdown Techniques; HEK293 Cells; Humans; Lung; Lung Neoplasms; Microsomes; Nicotiana; Nitrosamines; Oxidation-Reduction; Recombinant Proteins; RNA, Small Interfering; Smoking; Stereoisomerism	2018
Effects of cellular differentiation in human primary bronchial epithelial cells: Metabolism of 4-(methylnitrosamine)-1-(3-pyridyl)-1-butanone. Toxicology in vitro : an international journal published in association with BIBRA, 2019, Volume: 55 Topics: Bronchi; Cell Differentiation; Cells, Cultured; Epithelial Cells; Humans; Keto Acids; Nitrosamines; Toxicity Tests	2019
Does the implementation of smoke-free laws and smoking culture affect exposure to tobacco smoking? Results from 3 hospitality settings in South Korea. International journal of occupational medicine and environmental health, 2021, Jan-07, Volume: 34, Issue:1 Topics: Adult; Aged; Air Pollution, Indoor; Cotinine; Cross-Sectional Studies; Dust; Female; Hair; Humans; Male; Middle Aged; Nicotine; Nitrosamines; Occupational Exposure; Republic of Korea; Restaurants; Smoke-Free Policy; Tobacco Smoke Pollution	2021