Page last updated: 2024-09-03

4-(n-(iodoacetoxy)ethyl-n-methyl)amino-7-nitrobenz-2-oxa-1,3-diazole and cyclosporine

4-(n-(iodoacetoxy)ethyl-n-methyl)amino-7-nitrobenz-2-oxa-1,3-diazole has been researched along with cyclosporine in 1 studies

Compound Research Comparison

Studies
(4-(n-(iodoacetoxy)ethyl-n-methyl)amino-7-nitrobenz-2-oxa-1,3-diazole)
Trials
(4-(n-(iodoacetoxy)ethyl-n-methyl)amino-7-nitrobenz-2-oxa-1,3-diazole)
Recent Studies (post-2010)
(4-(n-(iodoacetoxy)ethyl-n-methyl)amino-7-nitrobenz-2-oxa-1,3-diazole)
Studies
(cyclosporine)
Trials
(cyclosporine)
Recent Studies (post-2010) (cyclosporine)
50033772170

Protein Interaction Comparison

ProteinTaxonomy4-(n-(iodoacetoxy)ethyl-n-methyl)amino-7-nitrobenz-2-oxa-1,3-diazole (IC50)cyclosporine (IC50)
ATP-binding cassette sub-family C member 3Homo sapiens (human)0.6315
Bile salt export pumpRattus norvegicus (Norway rat)0.6
Bile salt export pumpHomo sapiens (human)3.5
Interleukin-2Mus musculus (house mouse)0.005
ATP-dependent translocase ABCB1Mus musculus (house mouse)0.7
ATP-dependent translocase ABCB1Homo sapiens (human)1.6792
Cytochrome P450 3A4Homo sapiens (human)3.734
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 25.82
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)9.34
Cytochrome P450 3A5Homo sapiens (human)2.06
ATP-dependent translocase ABCB1Mus musculus (house mouse)4.8
Substance-K receptorHomo sapiens (human)4.139
Peptidyl-prolyl cis-trans isomerase BHomo sapiens (human)0.0088
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)9.34
Cytochrome P450 3A7Homo sapiens (human)2.06
Cytochrome P450 2C19Homo sapiens (human)7
Multidrug resistance-associated protein 1 Homo sapiens (human)3.5082
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)9.34
Peptidyl-prolyl cis-trans isomerase A Homo sapiens (human)0.0252
Peptidyl-prolyl cis-trans isomerase FKBP4Homo sapiens (human)0.016
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoformHomo sapiens (human)0.183
Peptidyl-prolyl cis-trans isomerase DHomo sapiens (human)0.0036
Sodium/bile acid cotransporterHomo sapiens (human)1
Reverse transcriptase/RNaseH Human immunodeficiency virus 10.455
Cytochrome P450 3A43 Homo sapiens (human)2.06
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Mus musculus (house mouse)0.57
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)1.3
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)4.3
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)0.95

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Casciano, CN; Clement, RP; Johnson, WW; Wang, EJ1

Other Studies

1 other study(ies) available for 4-(n-(iodoacetoxy)ethyl-n-methyl)amino-7-nitrobenz-2-oxa-1,3-diazole and cyclosporine

ArticleYear
Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites.
    Pharmaceutical research, 2003, Volume: 20, Issue:4

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Binding Sites; Biological Transport, Active; Biomarkers; Cells, Cultured; Drug Interactions; Fluorescent Dyes; Humans

2003