4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine has been researched along with scopolamine hydrobromide in 2 studies
| Studies (4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine) | Trials (4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine) | Recent Studies (post-2010) (4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine) | Studies (scopolamine hydrobromide) | Trials (scopolamine hydrobromide) | Recent Studies (post-2010) (scopolamine hydrobromide) |
|---|---|---|---|---|---|
| 42 | 0 | 9 | 7,548 | 563 | 1,401 |
| Protein | Taxonomy | 4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine (IC50) | scopolamine hydrobromide (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.003 | |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 0.006 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 0.006 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 0.006 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.0006 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 0.006 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 0.006 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.0026 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Balducci, C; Bonalumi, P; Carli, M; Millan, MJ; Samanin, R | 1 |
| Carli, M; Dekeyne, A; Di Cara, B; Gobert, A; Jaffard, R; Lestage, P; Meneses, A; Millan, MJ; Mocaer, E; Peglion, JL; Porsolt, R; Rivet, JM; Roux, S | 1 |
2 other study(ies) available for 4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine and scopolamine hydrobromide
| Article | Year |
|---|---|
S 15535, a benzodioxopiperazine acting as presynaptic agonist and postsynaptic 5-HT1A receptor antagonist, prevents the impairment of spatial learning caused by intrahippocampal scopolamine.
Topics: Animals; Hippocampus; Learning Disabilities; Male; Maze Learning; Piperazines; Pyridines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Scopolamine; Serotonin Antagonists; Serotonin Receptor Agonists; Synapses; Time Factors | 1999 |
The serotonin1A receptor partial agonist S15535 [4-(benzodioxan-5-yl)1-(indan-2-yl)piperazine] enhances cholinergic transmission and cognitive function in rodents: a combined neurochemical and behavioral analysis.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Aging; Amnesia; Animals; Dialysis; Discrimination Learning; Drug Interactions; Hippocampus; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Piperazines; Prefrontal Cortex; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Recognition, Psychology; Scopolamine; Serotonin Receptor Agonists; Spatial Behavior | 2004 |