4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine has been researched along with buspirone in 4 studies
| Studies (4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine) | Trials (4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine) | Recent Studies (post-2010) (4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine) | Studies (buspirone) | Trials (buspirone) | Recent Studies (post-2010) (buspirone) |
|---|---|---|---|---|---|
| 42 | 0 | 9 | 2,096 | 351 | 382 |
| Protein | Taxonomy | 4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine (IC50) | buspirone (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.025 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 1.75 | |
| Angiotensin-converting enzyme | Homo sapiens (human) | 0.024 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.323 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 2.125 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 4.16 | |
| D | Rattus norvegicus (Norway rat) | 0.12 | |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | 0.12 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0266 | |
| D(2) dopamine receptor | Bos taurus (cattle) | 4 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 4.16 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 1.077 | |
| D(1B) dopamine receptor | Rattus norvegicus (Norway rat) | 0.12 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 2.286 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.016 | |
| D(4) dopamine receptor | Rattus norvegicus (Norway rat) | 0.12 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 2.125 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.044 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.75 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 4.16 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.2055 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 3.9811 | |
| Alpha-2A adrenergic receptor | Bos taurus (cattle) | 0.025 | |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | 1.7 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.2666 | |
| Lysosomal alpha-glucosidase | Bos taurus (cattle) | 0.03 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chaput, C; Millan, MJ; Newman-Tancredi, A; Verrièle, L | 1 |
| Herremans, AH; Mos, J; Olivier, B; Van Drimmelen, M; Van Hest, A | 1 |
| Brocco, M; De Ladonchamps, B; Goument, B; Hjorth, S; Jaffard, R; Millan, MJ; Peglion, JL; Samanin, R; Schreiber, R; Spedding, M; Veiga, S | 1 |
| Danhof, M; Della Pasqua, O; Jochemsen, R; Kruk, M; Martin, D; Mocaër, E; Vis, P | 1 |
4 other study(ies) available for 4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine and buspirone
| Article | Year |
|---|---|
Labelling of recombinant human and native rat serotonin 5-HT1A receptors by a novel, selective radioligand, [3H]-S 15535: definition of its binding profile using agonists, antagonists and inverse agonists.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Affinity Labels; Animals; Binding, Competitive; CHO Cells; Cricetinae; Guanine Nucleotides; Hippocampus; Humans; Male; Membranes; Piperazines; Radiopharmaceuticals; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists | 1998 |
The putative 5-HT1A receptor antagonist DU125530 blocks the discriminative stimulus of the 5-HT1A receptor agonist flesinoxan in pigeons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Columbidae; Discrimination Learning; Fluvoxamine; Indoles; Pindolol; Piperazines; Pyridines; Pyrimidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Thiazoles | 1997 |
S 15535, a novel benzodioxopiperazine ligand of serotonin (5-HT)1A receptors: II. Modulation of hippocampal serotonin release in relation to potential anxiolytic properties.
Topics: Aggression; Animals; Anti-Anxiety Agents; Buspirone; Columbidae; Female; Hippocampus; Male; Mice; Mice, Inbred ICR; Motor Activity; Piperazines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Vocalization, Animal | 1997 |
Population pharmacokinetic-pharmacodynamic modelling of S 15535, a 5-HT(1A) receptor agonist, using a behavioural model in rats.
Topics: Animals; Anti-Anxiety Agents; Buspirone; Male; Nonlinear Dynamics; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Vocalization, Animal | 2001 |