Page last updated: 2024-09-05

4-(5,6-dimethyl-2-benzofuranyl)piperidine and naloxone

4-(5,6-dimethyl-2-benzofuranyl)piperidine has been researched along with naloxone in 2 studies

Compound Research Comparison

Studies
(4-(5,6-dimethyl-2-benzofuranyl)piperidine)
Trials
(4-(5,6-dimethyl-2-benzofuranyl)piperidine)
Recent Studies (post-2010)
(4-(5,6-dimethyl-2-benzofuranyl)piperidine)
Studies
(naloxone)
Trials
(naloxone)
Recent Studies (post-2010) (naloxone)
160020,1341,2573,321

Protein Interaction Comparison

ProteinTaxonomy4-(5,6-dimethyl-2-benzofuranyl)piperidine (IC50)naloxone (IC50)
Cytochrome P450 2D6Homo sapiens (human)2
Delta-type opioid receptorMus musculus (house mouse)0.043
Delta-type opioid receptorRattus norvegicus (Norway rat)0.0219
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0019
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0019
Mu-type opioid receptorHomo sapiens (human)0.0397
Delta-type opioid receptorHomo sapiens (human)0.1896
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.05
Kappa-type opioid receptorHomo sapiens (human)0.0795
Mu-type opioid receptorMus musculus (house mouse)0.0154
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.0089
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.0055

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Budziszewska, B; Grochmal, A; PrzegaliƄski, E1
Brown, P; Goldstein, DJ; Keiser, HR; Kulakowski, EC; Ropchak, TG1

Other Studies

2 other study(ies) available for 4-(5,6-dimethyl-2-benzofuranyl)piperidine and naloxone

ArticleYear
Oxaprotiline enantiomers stimulate ACTH and corticosterone secretion in the rat.
    Journal of neural transmission. General section, 1991, Volume: 85, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Benzylamines; Corticosterone; Dexamethasone; Diazepam; Dose-Response Relationship, Drug; Male; Maprotiline; Metergoline; Naloxone; Piperidines; Pyrimidines; Radioimmunoassay; Rats; Rats, Inbred Strains; Serotonin Antagonists; Stereoisomerism; Sulpiride; Sympathomimetics

1991
Naloxone reverses the serotonin dependent hypotensive action of CGP 6085 A.
    Life sciences, 1987, Sep-14, Volume: 41, Issue:11

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Fenclonine; Male; Methysergide; Naloxone; Piperidines; Rats; Serotonin; Serotonin Antagonists

1987