Page last updated: 2024-09-05

4-(5,6-dimethyl-2-benzofuranyl)piperidine and clomipramine

4-(5,6-dimethyl-2-benzofuranyl)piperidine has been researched along with clomipramine in 1 studies

Compound Research Comparison

Studies
(4-(5,6-dimethyl-2-benzofuranyl)piperidine)
Trials
(4-(5,6-dimethyl-2-benzofuranyl)piperidine)
Recent Studies (post-2010)
(4-(5,6-dimethyl-2-benzofuranyl)piperidine)
Studies
(clomipramine)
Trials
(clomipramine)
Recent Studies (post-2010) (clomipramine)
16002,929541304

Protein Interaction Comparison

ProteinTaxonomy4-(5,6-dimethyl-2-benzofuranyl)piperidine (IC50)clomipramine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.034
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.071
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.241
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.091
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.005
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.053
Alpha-2A adrenergic receptorHomo sapiens (human)0.707
Cytochrome P450 2D6Homo sapiens (human)3.9465
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.091
D(2) dopamine receptorHomo sapiens (human)0.413
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.005
Alpha-2B adrenergic receptorHomo sapiens (human)0.0505
Alpha-2C adrenergic receptorHomo sapiens (human)0.7065
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.005
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.17
D(1A) dopamine receptorHomo sapiens (human)1.113
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.0678
Histamine H2 receptorHomo sapiens (human)2.049
Alpha-1D adrenergic receptorHomo sapiens (human)0.18
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.067
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.034
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.005
5-hydroxytryptamine receptor 1DRattus norvegicus (Norway rat)0.005
5-hydroxytryptamine receptor 1FRattus norvegicus (Norway rat)0.005
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.005
5-hydroxytryptamine receptor 6Rattus norvegicus (Norway rat)0.005
Histamine H1 receptorRattus norvegicus (Norway rat)0.0002
Sodium-dependent serotonin transporterHomo sapiens (human)0.035
5-hydroxytryptamine receptor 7 Rattus norvegicus (Norway rat)0.005
5-hydroxytryptamine receptor 5ARattus norvegicus (Norway rat)0.005
5-hydroxytryptamine receptor 5BRattus norvegicus (Norway rat)0.005
Histamine H1 receptorHomo sapiens (human)0.085
D(3) dopamine receptorHomo sapiens (human)0.139
5-hydroxytryptamine receptor 3ARattus norvegicus (Norway rat)0.005
Trypanothione reductaseTrypanosoma brucei brucei3.4
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.239
Histamine H2 receptorCavia porcellus (domestic guinea pig)0.72
5-hydroxytryptamine receptor 6Homo sapiens (human)0.245
Voltage-dependent N-type calcium channel subunit alpha-1BHomo sapiens (human)9
Sodium-dependent dopamine transporter Homo sapiens (human)2.7615
5-hydroxytryptamine receptor 4 Rattus norvegicus (Norway rat)0.005
Sigma non-opioid intracellular receptor 1Homo sapiens (human)1.362
5-hydroxytryptamine receptor 3BRattus norvegicus (Norway rat)0.005

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Olpe, HR; Schellenberg, A1

Other Studies

1 other study(ies) available for 4-(5,6-dimethyl-2-benzofuranyl)piperidine and clomipramine

ArticleYear
The sensitivity of cortical neurons to serotonin: effect of chronic treatment with antidepressants, serotonin-uptake inhibitors and monoamine-oxidase-blocking drugs.
    Journal of neural transmission, 1981, Volume: 51, Issue:3-4

    Topics: Animals; Benzofurans; Cerebral Cortex; Clomipramine; Clorgyline; Desipramine; Electric Conductivity; gamma-Aminobutyric Acid; Male; Monoamine Oxidase Inhibitors; Neurons; Piperidines; Rats; Selegiline; Serotonin; Serotonin Antagonists

1981