Page last updated: 2024-09-03

4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid and tretinoin

4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid has been researched along with tretinoin in 4 studies

Compound Research Comparison

Studies
(4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid)
Trials
(4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid)
Recent Studies (post-2010)
(4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid)
Studies
(tretinoin)
Trials
(tretinoin)
Recent Studies (post-2010) (tretinoin)
140023,6541,0836,085

Protein Interaction Comparison

ProteinTaxonomy4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid (IC50)tretinoin (IC50)
Bile salt export pumpHomo sapiens (human)10
Amyloid-beta precursor proteinHomo sapiens (human)0.18
Adenosine receptor A3Homo sapiens (human)5.275
Retinoic acid receptor alphaHomo sapiens (human)2.2542
60 kDa heat shock protein, mitochondrialHomo sapiens (human)5.3
Retinoic acid receptor betaHomo sapiens (human)0.7537
Retinoic acid receptor alphaMus musculus (house mouse)0.0057
Retinoic acid receptor gamma Homo sapiens (human)0.0064
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)5.275
Retinoic acid receptor gammaMus musculus (house mouse)0.004
Retinoic acid receptor betaMus musculus (house mouse)0.005
Mitogen-activated protein kinase 1Homo sapiens (human)0.576
Nuclear receptor ROR-alphaHomo sapiens (human)0.1995
Alpha-synucleinHomo sapiens (human)3
Cellular retinoic acid-binding protein 1Gallus gallus (chicken)0.5233
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.358
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)5.275
Retinoic acid receptor RXR-gammaHomo sapiens (human)0.35
Nuclear receptor ROR-gammaHomo sapiens (human)0.1995
10 kDa heat shock protein, mitochondrialHomo sapiens (human)5.3
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1Homo sapiens (human)0.82
60 kDa chaperonin Escherichia coli6.7
10 kDa chaperonin Escherichia coli6.7
Nuclear receptor ROR-betaHomo sapiens (human)0.1259

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's3 (75.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chao, WR; Dawson, MI; Derdzinski, KA; Frenking, G; Hobbs, PD; Jetten, AM; Loew, GH; Napoli, JL; Sani, BP; Williams, JB1
Bernardon, JM; Charpentier, B; Eustache, J; Martin, B; Michel, S; Millois, C; Shroot, B1
Dallery, N; Dautrevaux, M; Formstecher, P; Grillier, I; Sablonnière, B1
Blomhoff, HK; Blomhoff, R; Dawson, MI; Gandhi, U; Lømo, J; Natarajan, V; Smeland, EB; Ulven, S1

Other Studies

4 other study(ies) available for 4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid and tretinoin

ArticleYear
Effect of structural modifications in the C7-C11 region of the retinoid skeleton on biological activity in a series of aromatic retinoids.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:7

    Topics: Animals; Cells, Cultured; Chemical Phenomena; Chemistry; Chick Embryo; Male; Molecular Conformation; Rabbits; Retinoids; Spectrophotometry, Ultraviolet; Structure-Activity Relationship

1989
Synthesis, structure-affinity relationships, and biological activities of ligands binding to retinoic acid receptor subtypes.
    Journal of medicinal chemistry, 1995, Dec-22, Volume: 38, Issue:26

    Topics: Animals; Cell Differentiation; Magnetic Resonance Spectroscopy; Mice; Receptors, Retinoic Acid; Recombinant Proteins; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Retinoids; Structure-Activity Relationship; Teratocarcinoma; Tretinoin; Tumor Cells, Cultured

1995
Physicochemical parameters affecting the charcoal adsorption assay for quantitative retinoid-binding measurement.
    Analytical biochemistry, 1994, Feb-15, Volume: 217, Issue:1

    Topics: Adsorption; Buffers; Charcoal; Chemical Phenomena; Chemistry, Physical; Dextrans; Hydrogen-Ion Concentration; Kinetics; Receptors, Retinoic Acid; Retinoids; Sensitivity and Specificity; Suspensions; Tretinoin; Tritium

1994
RAR-, not RXR, ligands inhibit cell activation and prevent apoptosis in B-lymphocytes.
    Journal of cellular physiology, 1998, Volume: 175, Issue:1

    Topics: Alitretinoin; Apoptosis; B-Lymphocytes; CD40 Antigens; CD40 Ligand; DNA; DNA-Binding Proteins; Gene Expression; Humans; Immunoglobulin M; Interleukin-4; Ligands; Lymphocyte Activation; Membrane Glycoproteins; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; Transcription Factors; Transcription, Genetic; Transfection; Tretinoin

1998