Page last updated: 2024-09-03

4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid and 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid

4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid has been researched along with 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid in 4 studies

Compound Research Comparison

Studies
(4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid)
Trials
(4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid)
Recent Studies (post-2010)
(4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid)
Studies
(4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid)
Trials
(4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid)
Recent Studies (post-2010) (4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid)
1400174229

Protein Interaction Comparison

ProteinTaxonomy4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid (IC50)4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid (IC50)
Retinoic acid receptor alphaHomo sapiens (human)0.036
Retinoic acid receptor betaHomo sapiens (human)0.005
Retinoic acid receptor gamma Homo sapiens (human)0.026

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chao, WR; Dawson, MI; Derdzinski, KA; Frenking, G; Hobbs, PD; Jetten, AM; Loew, GH; Napoli, JL; Sani, BP; Williams, JB1
Balaban, AT; Bonchev, D; Mountain, CF; Seitz, WA1
Bernardon, JM; Charpentier, B; Eustache, J; Martin, B; Michel, S; Millois, C; Shroot, B1
Balaguer, P; Lemaire, G; Michel, S; Rahmani, R1

Other Studies

4 other study(ies) available for 4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid and 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid

ArticleYear
Effect of structural modifications in the C7-C11 region of the retinoid skeleton on biological activity in a series of aromatic retinoids.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:7

    Topics: Animals; Cells, Cultured; Chemical Phenomena; Chemistry; Chick Embryo; Male; Molecular Conformation; Rabbits; Retinoids; Spectrophotometry, Ultraviolet; Structure-Activity Relationship

1989
Modeling the anticarcinogenic action of retinoids by making use of the OASIS method. 3. Inhibition of the induction of ornithine decarboxylase by arotinoids.
    Journal of medicinal chemistry, 1994, Jul-22, Volume: 37, Issue:15

    Topics: Anticarcinogenic Agents; Models, Molecular; Molecular Conformation; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Retinoids; Structure-Activity Relationship

1994
Synthesis, structure-affinity relationships, and biological activities of ligands binding to retinoic acid receptor subtypes.
    Journal of medicinal chemistry, 1995, Dec-22, Volume: 38, Issue:26

    Topics: Animals; Cell Differentiation; Magnetic Resonance Spectroscopy; Mice; Receptors, Retinoic Acid; Recombinant Proteins; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Retinoids; Structure-Activity Relationship; Teratocarcinoma; Tretinoin; Tumor Cells, Cultured

1995
Activation of retinoic acid receptor-dependent transcription by organochlorine pesticides.
    Toxicology and applied pharmacology, 2005, Jan-01, Volume: 202, Issue:1

    Topics: Animals; Benzoates; COS Cells; Cytochrome P-450 Enzyme System; Enzyme Induction; HeLa Cells; Humans; Hydrocarbons, Chlorinated; Insecticides; Naphthalenes; Receptors, Retinoic Acid; Retinoic Acid 4-Hydroxylase; Retinoids; Transcriptional Activation

2005