Compounds > 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol
Page last updated: 2024-09-03

4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol and promethazine

4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol has been researched along with promethazine in 1 studies

Compound Research Comparison

Studies
(4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol)		Trials
(4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol)		Recent Studies (post-2010)
(4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol)		Studies
(promethazine)		Trials
(promethazine)		Recent Studies (post-2010) (promethazine)
701293,110299235

Protein Interaction Comparison

ProteinTaxonomy4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol (IC50)promethazine (IC50)
Spike glycoproteinBetacoronavirus England 15.86
Replicase polyprotein 1abBetacoronavirus England 15.86
Transmembrane protease serine 2Homo sapiens (human)5.86
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.012
Procathepsin LHomo sapiens (human)5.86
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)4.238
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.035
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.0076
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.0046
Alpha-2A adrenergic receptorHomo sapiens (human)0.681
Replicase polyprotein 1aSevere acute respiratory syndrome-related coronavirus5.86
Replicase polyprotein 1abHuman coronavirus 229E5.86
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirus5.86
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 25.86
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.014
D(2) dopamine receptorHomo sapiens (human)0.4395
Alpha-2B adrenergic receptorHomo sapiens (human)0.053
Alpha-2C adrenergic receptorHomo sapiens (human)2.431
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)2.596
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.02
D(1A) dopamine receptorHomo sapiens (human)2.744
Sodium-dependent noradrenaline transporter Homo sapiens (human)4.238
Histamine H2 receptorHomo sapiens (human)1.165
Alpha-1D adrenergic receptorHomo sapiens (human)0.183
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.045
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.012
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)2.596
Sodium-dependent serotonin transporterHomo sapiens (human)5.8
Histamine H1 receptorHomo sapiens (human)0.0041
D(3) dopamine receptorHomo sapiens (human)0.559
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.068
5-hydroxytryptamine receptor 6Homo sapiens (human)2.429
Spike glycoproteinSevere acute respiratory syndrome-related coronavirus5.86
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.287
Angiotensin-converting enzyme 2 Homo sapiens (human)5.86

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Furukori, H; Inoue, Y; Kaneko, S; Kondo, T; Mihara, K; Otani, K; Suzuki, A; Yasui-Furukori, N1

Trials

1 trial(s) available for 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol and promethazine

ArticleYear
Histamine H1-receptor antagonists, promethazine and homochlorcyclizine, increase the steady-state plasma concentrations of haloperidol and reduced haloperidol.
    Therapeutic drug monitoring, 2003, Volume: 25, Issue:2

    Topics: Adult; Aged; Antipsychotic Agents; Cyclizine; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; Haloperidol; Histamine H1 Antagonists; Humans; Male; Middle Aged; Promethazine; Schizophrenia

2003