4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol has been researched along with prochlorperazine in 1 studies
| Studies (4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol) | Trials (4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol) | Recent Studies (post-2010) (4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol) | Studies (prochlorperazine) | Trials (prochlorperazine) | Recent Studies (post-2010) (prochlorperazine) |
|---|---|---|---|---|---|
| 70 | 12 | 9 | 1,125 | 206 | 110 |
| Protein | Taxonomy | 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol (IC50) | prochlorperazine (IC50) |
|---|---|---|---|
| Mcl-1 | Homo sapiens (human) | 3.7733 | |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.078 | |
| Bile salt export pump | Homo sapiens (human) | 10 | |
| Cytochrome P450 1A2 | Homo sapiens (human) | 2 | |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | 5.684 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.4 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 3.112 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 1.363 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.22 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.169 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.3 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 1.013 | |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | 1.8481 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.011 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.01 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.082 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.95 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 1.514 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.155 | |
| D(4) dopamine receptor | Homo sapiens (human) | 2.311 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 0.4 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.034 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.0071 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.078 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.95 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 1.169 | |
| Pleiotropic ABC efflux transporter of multiple drugs | Saccharomyces cerevisiae S288C | 1.7 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.024 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.013 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.102 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.267 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 1.735 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 1.8481 | |
| Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | 1.8481 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.054 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
1 other study(ies) available for 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol and prochlorperazine
| Article | Year |
|---|---|
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |