4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol has been researched along with furafylline in 1 studies
Studies (4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol) | Trials (4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol) | Recent Studies (post-2010) (4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol) | Studies (furafylline) | Trials (furafylline) | Recent Studies (post-2010) (furafylline) |
---|---|---|---|---|---|
70 | 12 | 9 | 121 | 2 | 42 |
Protein | Taxonomy | 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol (IC50) | furafylline (IC50) |
---|---|---|---|
Cytochrome P450 1A2 | Homo sapiens (human) | 2.5292 | |
Cytochrome P450 2C19 | Homo sapiens (human) | 0.3 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Belpaire, FM; Pan, L | 1 |
1 other study(ies) available for 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol and furafylline
Article | Year |
---|---|
In vitro study on the involvement of CYP1A2, CYP2D6 and CYP3A4 in the metabolism of haloperidol and reduced haloperidol.
Topics: Biotransformation; Child; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dopamine Antagonists; Enzyme Inhibitors; Haloperidol; Humans; Isoenzymes; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Oxidation-Reduction; Theophylline | 1999 |