4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol and flurbiprofen
4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol has been researched along with flurbiprofen in 2 studies
Compound Research Comparison
Studies (4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol) | Trials (4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol) | Recent Studies (post-2010) (4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol) | Studies (flurbiprofen) | Trials (flurbiprofen) | Recent Studies (post-2010) (flurbiprofen) |
---|---|---|---|---|---|
70 | 12 | 9 | 2,072 | 466 | 575 |
Protein Interaction Comparison
Protein | Taxonomy | 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol (IC50) | flurbiprofen (IC50) |
---|---|---|---|
Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 0.1683 | |
Prostaglandin G/H synthase 1 | Homo sapiens (human) | 0.6754 | |
Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.574 | |
Aldo-keto reductase family 1 member C3 | Homo sapiens (human) | 1.56 | |
Prostaglandin G/H synthase 2 | Mus musculus (house mouse) | 0.5 | |
Solute carrier family 22 member 6 | Homo sapiens (human) | 1.5 | |
Prostaglandin G/H synthase 1 | Rattus norvegicus (Norway rat) | 0.17 |
Research
Studies (2)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (50.00) | 29.6817 |
2010's | 1 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Abagyan, R; Cottam, HB; Kaler, G; Saldanha, SA; Taylor, SS | 1 |
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
Other Studies
2 other study(ies) available for 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol and flurbiprofen
Article | Year |
---|---|
Assay principle for modulators of protein-protein interactions and its application to non-ATP-competitive ligands targeting protein kinase A.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Binding, Competitive; Biological Assay; Cyclic AMP-Dependent Protein Kinases; Fluorescence Polarization; Ligands; Molecular Sequence Data; Protein Binding; Substrate Specificity | 2006 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |