Page last updated: 2024-09-03

4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol and flurbiprofen

4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol has been researched along with flurbiprofen in 2 studies

Compound Research Comparison

Studies
(4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol)
Trials
(4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol)
Recent Studies (post-2010)
(4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol)
Studies
(flurbiprofen)
Trials
(flurbiprofen)
Recent Studies (post-2010) (flurbiprofen)
701292,072466575

Protein Interaction Comparison

ProteinTaxonomy4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol (IC50)flurbiprofen (IC50)
Prostaglandin G/H synthase 1Ovis aries (sheep)0.1683
Prostaglandin G/H synthase 1Homo sapiens (human)0.6754
Prostaglandin G/H synthase 2Homo sapiens (human)0.574
Aldo-keto reductase family 1 member C3Homo sapiens (human)1.56
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.5
Solute carrier family 22 member 6Homo sapiens (human)1.5
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.17

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abagyan, R; Cottam, HB; Kaler, G; Saldanha, SA; Taylor, SS1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1

Other Studies

2 other study(ies) available for 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol and flurbiprofen

ArticleYear
Assay principle for modulators of protein-protein interactions and its application to non-ATP-competitive ligands targeting protein kinase A.
    Analytical chemistry, 2006, Dec-15, Volume: 78, Issue:24

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Binding, Competitive; Biological Assay; Cyclic AMP-Dependent Protein Kinases; Fluorescence Polarization; Ligands; Molecular Sequence Data; Protein Binding; Substrate Specificity

2006
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
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