Page last updated: 2024-09-03

4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol and dextrorphan

4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol has been researched along with dextrorphan in 1 studies

Compound Research Comparison

Studies
(4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol)
Trials
(4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol)
Recent Studies (post-2010)
(4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol)
Studies
(dextrorphan)
Trials
(dextrorphan)
Recent Studies (post-2010) (dextrorphan)
701294564555

Protein Interaction Comparison

ProteinTaxonomy4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol (IC50)dextrorphan (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)6
Glutamate receptor ionotropic, NMDA 1Homo sapiens (human)0.773
Glutamate receptor ionotropic, NMDA 2AHomo sapiens (human)1.3
Glutamate receptor ionotropic, NMDA 2BHomo sapiens (human)0.246

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Flockhart, DA; Kane, K; Shin, JG1

Other Studies

1 other study(ies) available for 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol and dextrorphan

ArticleYear
Potent inhibition of CYP2D6 by haloperidol metabolites: stereoselective inhibition by reduced haloperidol.
    British journal of clinical pharmacology, 2001, Volume: 51, Issue:1

    Topics: Binding, Competitive; Biomarkers; Cytochrome P-450 CYP2D6 Inhibitors; Dextrorphan; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Haloperidol; Humans; In Vitro Techniques; Kinetics; Microsomes, Liver; Phenols; Propanols; Stereoisomerism

2001