4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol has been researched along with dextrorphan in 1 studies
Studies (4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol) | Trials (4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol) | Recent Studies (post-2010) (4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol) | Studies (dextrorphan) | Trials (dextrorphan) | Recent Studies (post-2010) (dextrorphan) |
---|---|---|---|---|---|
70 | 12 | 9 | 456 | 45 | 55 |
Protein | Taxonomy | 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol (IC50) | dextrorphan (IC50) |
---|---|---|---|
Solute carrier family 22 member 1 | Homo sapiens (human) | 6 | |
Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | 0.773 | |
Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | 1.3 | |
Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | 0.246 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Flockhart, DA; Kane, K; Shin, JG | 1 |
1 other study(ies) available for 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol and dextrorphan
Article | Year |
---|---|
Potent inhibition of CYP2D6 by haloperidol metabolites: stereoselective inhibition by reduced haloperidol.
Topics: Binding, Competitive; Biomarkers; Cytochrome P-450 CYP2D6 Inhibitors; Dextrorphan; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Haloperidol; Humans; In Vitro Techniques; Kinetics; Microsomes, Liver; Phenols; Propanols; Stereoisomerism | 2001 |