4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone has been researched along with zaprinast in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (22.22) | 18.7374 |
| 1990's | 8 (44.44) | 18.2507 |
| 2000's | 6 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bristol, JA; Cain, MH; Weishaar, RE | 1 |
| André, AC; Némoz, G; Pacheco, H; Picq, M; Prigent, AF | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Heaslip, R; Nielson, CP; Sturm, RJ; Vestal, RE | 1 |
| Weiss, RM; Wheeler, MA | 1 |
| Némoz, G; Pacheco, H; Picq, M; Prigent, AF | 1 |
| Bonsi, P; Giorgi, M; Paggi, P; Squitti, R; Toschi, G | 1 |
| Chen, J; Meeker, SN; Undem, BJ | 1 |
| Dahl, SG; Lagente, V; Payne, AN; Planquois, JM; Ruffin-Morin, Y | 2 |
| Bakre, MM; Visweswariah, SS | 1 |
| Horita, T; Kasugai, S; Miyamoto, K; Ohya, K; Waki, Y | 1 |
| Boichot, E; Germain, N; Lagente, V; Planquois, JM | 1 |
| Cherry, JA; Pho, V; Thompson, BE | 1 |
| Boon, K; Fooks, HM; Hourani, SM; Prentice, DJ | 1 |
| Breese, E; Del Soldato, P; Mitchell, J; Warner, T; Wood, E; Zacharowski, P | 1 |
| Kaneda, T; Nakajyo, S; Shimizu, K; Urakawa, N; Watanabe, A | 1 |
| Chai, Y; Lin, YF; Mao, X | 1 |
1 review(s) available for 4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone and zaprinast
| Article | Year |
|---|---|
A new generation of phosphodiesterase inhibitors: multiple molecular forms of phosphodiesterase and the potential for drug selectivity.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Platelets; Calmodulin; Cardiotonic Agents; Guinea Pigs; Humans; Hypersensitivity; In Vitro Techniques; Lung Diseases; Myocardium; Platelet Aggregation; Substrate Specificity | 1985 |
17 other study(ies) available for 4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone and zaprinast
| Article | Year |
|---|---|
Pentasubstituted quercetin analogues as selective inhibitors of particulate 3':5'-cyclic-AMP phosphodiesterase from rat brain.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Brain; Chemical Phenomena; Chemistry; Flavonoids; Quercetin; Rats | 1982 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Effects of selective phosphodiesterase inhibitors on the polymorphonuclear leukocyte respiratory burst.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenergic beta-Agonists; Adult; Calcimycin; Chromatography, Ion Exchange; Humans; Isoenzymes; Isoproterenol; Middle Aged; Milrinone; Neutrophils; Oxygen Consumption; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Purinones; Pyridazines; Pyridones; Pyrrolidinones; Rolipram; Superoxides | 1990 |
Insulin activation of cyclic AMP phosphodiesterase in intact ureteral segments.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Amrinone; Animals; Cyclic GMP; Enzyme Activation; Female; Guinea Pigs; Insulin; Kinetics; Milrinone; Purinones; Pyridones; Pyrrolidinones; Rolipram; Ureter | 1988 |
Selective inhibition of separated forms of cyclic nucleotide phosphodiesterase from rat heart by some cardio- or vaso-active butenolide derivatives.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 4-Butyrolactone; Animals; Benzofurans; Benzoin; Cytosol; Furans; Isoenzymes; Myocardium; Phosphodiesterase Inhibitors; Purinones; Rats; Vasodilator Agents | 1982 |
Activities of 3':5' cyclic nucleotide phosphodiesterases in the superior cervical ganglion of rat: characterization, compartmentalization and observations in young and old animals.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Age Factors; Animals; Cyclic AMP; Cyclic GMP; Kinetics; Male; Purinones; Rats; Rats, Sprague-Dawley; Superior Cervical Ganglion | 1994 |
Inhibition of neurally mediated nonadrenergic, noncholinergic contractions of guinea pig bronchus by isozyme-selective phosphodiesterase inhibitors.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Bronchi; Bronchoconstriction; Electric Stimulation; Guanidines; Guinea Pigs; Isoenzymes; Male; Phosphodiesterase Inhibitors; Purinones; Pyridazines; Pyrrolidinones; Rolipram; Vagus Nerve | 1994 |
Salbutamol potentiates the relaxant effects of selective phosphodiesterase inhibitors on guinea pig isolated trachea.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenergic beta-Agonists; Albuterol; Animals; Drug Synergism; Guanidines; Guinea Pigs; Histamine; In Vitro Techniques; Male; Milrinone; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Osmolar Concentration; Phosphodiesterase Inhibitors; Purinones; Pyridazines; Pyridones; Pyrrolidinones; Rolipram; Theophylline; Trachea | 1996 |
Differential inhibition by selective phosphodiesterase inhibitors of antigen, LTC4 and histamine-induced contraction of guinea-pig isolated trachea.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Bronchoconstrictor Agents; Bronchodilator Agents; Guanidines; Guinea Pigs; Histamine Antagonists; In Vitro Techniques; Leukotriene C4; Male; Milrinone; Muscle Tonus; Ovalbumin; Phosphodiesterase Inhibitors; Purinones; Pyridazines; Pyridones; Pyrrolidinones; Rolipram; Theophylline; Trachea | 1996 |
Dual regulation of heat-stable enterotoxin-mediated cGMP accumulation in T84 cells by receptor desensitization and increased phosphodiesterase activity.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Bacterial Toxins; Cell Line; Cell Membrane; Cyclic GMP; Enterotoxins; Escherichia coli Proteins; Guanylate Cyclase; Humans; Kinetics; Milrinone; Phenothiazines; Purinones; Pyridones | 1997 |
Reduction of bone loss by denbufylline, an inhibitor of phosphodiesterase 4.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Bone Marrow Cells; Bone Resorption; Bucladesine; Calcification, Physiologic; Carcinoma 256, Walker; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 4; Female; Mice; Milrinone; Osteoclasts; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Purinones; Pyridones; Rats; Rats, Wistar; Xanthines | 1997 |
Reduced airway hyperresponsiveness by phosphodiesterase 3 and 4 inhibitors in guinea-pigs.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetylcholine; Analysis of Variance; Animals; Guinea Pigs; Male; Milrinone; Ovalbumin; Phosphodiesterase Inhibitors; Purinones; Respiratory Hypersensitivity | 1999 |
Diazepam and rolipram differentially inhibit cyclic AMP-specific phosphodiesterases PDE4A1 and PDE4B3 in the mouse.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cloning, Molecular; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Diazepam; DNA, Complementary; Humans; Immunoblotting; Mice; Milrinone; Molecular Sequence Data; Molecular Structure; Phosphodiesterase Inhibitors; Purinones; Rats; Rolipram; Sequence Homology, Amino Acid | 2001 |
Role of cyclic nucleotides in vasodilations of the rat thoracic aorta induced by adenosine analogues.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetylcholine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Male; Nitroprusside; Nucleotides, Cyclic; Oxadiazoles; Purinones; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents | 2001 |
NSAIDs increase GM-CSF release by human synoviocytes: comparison with nitric oxide-donating derivatives.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blotting, Western; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Flurbiprofen; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Indomethacin; Membrane Proteins; Naproxen; Nitric Oxide Donors; Nitroprusside; Phosphodiesterase Inhibitors; Prostaglandin-Endoperoxide Synthases; Purinones; Synovial Membrane; Time Factors | 2005 |
Effects of various selective phosphodiesterase inhibitors on carbachol-induced contraction and cyclic nucleotide contents in the guinea pig gall bladder.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Animals; Carbachol; Cyclic AMP; Cyclic GMP; Gallbladder; Guinea Pigs; Male; Milrinone; Muscle Contraction; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Purinones; Vinca Alkaloids | 2005 |
Dual regulation of the ATP-sensitive potassium channel by caffeine.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine Triphosphate; Animals; Caffeine; Carbazoles; Cell Line; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Indoles; Insulin; Insulin Secretion; Ion Channel Gating; Islets of Langerhans; Isoquinolines; Muscle, Smooth; Pancreas; Potassium Channels; Protein Isoforms; Purinones; Rats; Sulfonamides | 2007 |