4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone has been researched along with colforsin in 86 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (34.88) | 18.7374 |
| 1990's | 39 (45.35) | 18.2507 |
| 2000's | 14 (16.28) | 29.6817 |
| 2010's | 3 (3.49) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Byczko, Z; Murphy, MG | 2 |
| Hassall, GA; Parrott, DP; Souness, JE | 1 |
| Chabardès, D; Montégut, M; Siaume-Perez, S; Zhou, Y | 1 |
| Schwarzschild, MA; Zigmond, RE | 1 |
| Lugnier, C; Muller, B; Stoclet, JC | 1 |
| Hanafusa, T; Kitajima, K; Mashita, K; Matsui, I; Miyagawa, J; Mori-Tanaka, M; Oda, Y; Tajima, K; Tarui, S | 1 |
| Nicholson, D; Reid, A; Sawynok, J | 1 |
| Nicholson, D; Sawynok, J; White, TD | 1 |
| Heppel, LA; Huang, NN; Wang, DJ | 1 |
| Aghajanian, GK; Wang, YY | 2 |
| Cochaux, P; Dumont, JE; Van Sande, J | 1 |
| Alberts, P; Ogren, VR; Sellström, AI | 1 |
| Bertram, JS; Loewenstein, WR; Mehta, PP | 1 |
| Conti, M; Geremia, R; Monaco, L; Stefanini, M | 1 |
| Eckhardt, L; Imamura, K; Kimura, T; Schulz, I | 1 |
| Madison, DV; Nicoll, RA | 1 |
| Malemud, CJ; Mills, TM; Papay, RS; Shuckett, R | 1 |
| Hoffman, BB; Lee, CH; Tsujimoto, G | 1 |
| Fredholm, BB; Lerner, U; Ransjö, M | 1 |
| Klein, DC; Sugden, D | 1 |
| Levitan, IB; Lotshaw, DP | 1 |
| Ahrén, KE; Sender Baum, MG | 1 |
| Madelian, V; Martin, DL; Shain, W | 1 |
| Greengard, P; Huganir, RL; Miles, K | 1 |
| Dahler, H; Kaplan, C; Lane, B; Malbon, CC; Mazella, J; Tseng, A; Tseng, L | 1 |
| Adams, M; Boarder, MR; Marriott, D | 1 |
| Kammer, GM; Mitchell, E | 1 |
| Bertram, JS; Matsukawa, T | 1 |
| Chern, YJ; Kim, KT; Slakey, LL; Westhead, EW | 1 |
| Averill, LE; Kammer, GM; Stein, RL | 1 |
| Chen, GA; Huang, JR; Tseng, L | 1 |
| Collin, JP; Martin, C; Voisin, P | 1 |
| Bertram, JS; Faletto, MB | 1 |
| Dohi, T; Kitayama, S; Morita, K; Tsujimoto, A | 1 |
| Dhillon, GS; Honnor, RC; Londos, C | 1 |
| Strong, JA | 1 |
| Dalaker, K; Prydz, H | 1 |
| Cook, GH; Fradkin, JE; Kilhoffer, MC; Wolff, J | 1 |
| Kelly, JS; Larkman, PM; Takahashi, T | 1 |
| Cole, RL; Green, D; Grossbard, SJ; Hyman, SE; Konradi, C; Leveque, JC; Pollack, AE; Senatus, P | 1 |
| Albert, DA; Rozengurt, E | 1 |
| Herman, P; Marianowski, R; Martin, F; Tran Ba Huy, P; Tu, TY | 1 |
| Barry, T; Delamere, F; Holland, E; Knox, A; Pavord, I | 1 |
| Fiscus, RR; Zhou, HL | 1 |
| al-Essa, LY; Kohno, K; Niwa, M; Nozaki, M; Tsurumi, K | 1 |
| Chetkovich, DM; Sweatt, JD | 1 |
| Barrett, JA; Derian, CK; Rao, PE; Santulli, RJ; Solomon, HF | 1 |
| Fuller, LZ; Jackson, BA; Yingling, JD | 1 |
| Ahlström, M; Törnquist, K | 1 |
| Davis, BB; Thomas, DJ; Zenser, TV | 1 |
| Gewitz, MH; Hintze, TH; Mathew, R; Wang, J; Wolin, MS | 1 |
| Boichot, E; Germain, N; Hichami, A; Lagente, V; Legrand, A; Moodley, I | 1 |
| Krause, G; Kumar, R; Meyers, A; Prasad, KN | 1 |
| Ohia, SE; Opere, CA | 1 |
| Harmon, CS; Nevins, TD | 1 |
| Handwerger, S; Jikihara, H; Poisner, AM | 1 |
| Chang, YH; Chern, Y; Ching, YH; Conti, M; Lai, HL; Lee, YC | 1 |
| Baba, J; Miyashiro, M; Sawa, A; Yamashita, N | 1 |
| Brundege, JM; Diao, L; Dunwiddie, TV; Proctor, WR | 1 |
| Lawrie, AM; Simpson, AW; Zolle, O | 1 |
| Cooper, DM; Fagan, KA; Mons, N | 1 |
| Maurice, DH; Palmer, D; Tsoi, K | 1 |
| Gean, PW; Lu, KT | 1 |
| Hara, A; Kanamori, Y; Kozawa, O; Matsuno, H; Mori, H; Niwa, M; Uematsu, T; Yoshimi, N | 1 |
| Karle, CA; Kathöfer, S; Kiehn, J; Kübler, W; Schöls, W; Thomas, D; Zhang, W | 1 |
| Hashimoto, T; Ishii-Nozawa, R; Kunitomo, M; Shinozuka, K; Takeuchi, K | 1 |
| Cederbaum, SD; Ignarro, LJ; Mori, M; Morris, SM; Wei, LH | 1 |
| Mitchell, JA; Warner, TD; Wood, EG; Woods, M | 1 |
| Carew, TJ; Purcell, AL | 1 |
| Kim, KT; Kim, TD; Lee, JU; Seong, JK; Suh, BC | 1 |
| Absher, PM; Dunkerley, HA; Jimmo, SL; Maurice, DH; Netherton, SJ; Palmer, D; Raymond, DR; Russell, JC; Sage, EH; Tilley, DG; Vernon, RB | 1 |
| Boehm, S; Freissmuth, M; Just, H; Klinger, M; Korkhov, VM; Kudlacek, O; Nanoff, C; Pankevych, H; Vartian, N; Yang, Q | 1 |
| Johnson, SW; Shen, KZ | 1 |
| Gillespie, JI | 1 |
| Boehm, S; Dorostkar, MM; Edelbauer, H; Lechner, SG; Mayer, M; Pankevych, H | 1 |
| Alonso, AA; Bourque, CW; Khawaja, FA | 1 |
| Carter, RL; Maurice, DH; Raymond, DR; Wilson, LS | 1 |
| Dumas, A; Dussault, AA; Laflamme, C; Michaud, A; Pouliot, M; St-Onge, M | 1 |
| Jackson, EK; Mi, Z | 1 |
| Chen, CC; Hsu, KS; Huang, CC; Yang, CH | 1 |
| Birowo, P; Kedia, GT; Kuczyk, MA; Rahardjo, D; Sandner, P; Scheller, F; Sonnenberg, JE; Thon, WF; Uckert, S | 1 |
| Kedia, GT; Kuczyk, MA; Merseburger, AS; Polat, H; Ückert, S | 1 |
86 other study(ies) available for 4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone and colforsin
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Non-eicosanoid functions of essential fatty acids: regulation of adenosine-related functions in cultured neuroblastoma cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Deaminase; Animals; Calcium; Colforsin; Cyclic AMP; Eicosanoids; Fatty Acids, Essential; Fatty Acids, Unsaturated; Neuroblastoma; Receptors, Purinergic; Theophylline; Tumor Cells, Cultured | 1992 |
Inhibition of pig aortic smooth muscle cell DNA synthesis by selective type III and type IV cyclic AMP phosphodiesterase inhibitors.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Aorta; Cell Division; Colforsin; Cyclic AMP; DNA Replication; Guanidines; Isoenzymes; Isoquinolines; Muscle, Smooth, Vascular; Pyridazines; Pyrrolidinones; Rolipram; Swine; Tetrahydroisoquinolines; Thymidine | 1992 |
Further studies of the mechanism(s) of polyunsaturated-fatty-acid-mediated increases in intracellular cAMP formation in N1E-115 neuroblastoma cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 5'-Nucleotidase; Adenosine; Basal Metabolism; Colforsin; Cyclic AMP; Dipyridamole; Linoleic Acid; Linoleic Acids; Neuroblastoma; Neurons; Pentostatin; Receptors, Purinergic; Tumor Cells, Cultured | 1992 |
Two mechanisms of inhibition by prostaglandin E2 of hormone-dependent cell cAMP in the rat collecting tubule.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Animals; Arginine Vasopressin; Colforsin; Cyclic AMP; Dinoprostone; Indomethacin; Isoproterenol; Kidney Tubules, Collecting; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Signal Transduction; Xanthines | 1990 |
Effects of peptides of the secretin-glucagon family and cyclic nucleotides on tyrosine hydroxylase activity in sympathetic nerve endings.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Drug Synergism; Heart Ventricles; Male; Nerve Endings; Nitroprusside; Protein Kinase C; Rats; Rats, Inbred Strains; Second Messenger Systems; Secretin; Sympathetic Nervous System; Tyrosine 3-Monooxygenase; Vasoactive Intestinal Peptide | 1991 |
Involvement of rolipram-sensitive cyclic AMP phosphodiesterase in the regulation of cardiac contraction.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Atenolol; Calcium Chloride; Colforsin; Guinea Pigs; In Vitro Techniques; Male; Myocardial Contraction; Phosphodiesterase Inhibitors; Pyrazines; Pyrrolidinones; Reserpine; Rolipram; Stereoisomerism; Xanthines | 1990 |
Inhibitory effects of ionophore A23187 on the release of thyroid hormone and colloid reabsorption in mouse thyroid glands.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Calcimycin; Calcium; Colforsin; Colloids; Cyclic AMP; Epithelium; Mice; Mice, Inbred BALB C; Microscopy, Electron; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 1991 |
Effects of forskolin and phosphodiesterase inhibitors on spinal antinociception by morphine.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Colforsin; Cyclic AMP; Injections, Spinal; Male; Morphine; Nociceptors; Phosphodiesterase Inhibitors; Rats; Rats, Inbred Strains; Spinal Cord | 1991 |
Forskolin and phosphodiesterase inhibitors release adenosine but inhibit morphine-evoked release of adenosine from spinal cord synaptosomes.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 5'-Nucleotidase; Adenosine; Animals; Colforsin; Cyclic AMP; In Vitro Techniques; Morphine; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rolipram; Spinal Cord; Synaptosomes | 1991 |
Extracellular ATP shows synergistic enhancement of DNA synthesis when combined with agents that are active in wound healing or as neurotransmitters.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Imidodiphosphate; Animals; Cells, Cultured; Cholera Toxin; Colforsin; DNA; DNA Replication; Drug Synergism; Epidermal Growth Factor; Insulin; Keratinocytes; Kinetics; Mice; Mice, Inbred BALB C; Neurotransmitter Agents; Platelet-Derived Growth Factor; Thymidine; Transforming Growth Factors; Tritium; Vasoactive Intestinal Peptide; Wound Healing | 1990 |
Excitation of locus coeruleus neurons by vasoactive intestinal peptide: role of a cAMP and protein kinase A.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Carrier Proteins; Colforsin; Cyclic AMP; Electric Conductivity; Electrophysiology; Intracellular Signaling Peptides and Proteins; Locus Coeruleus; Male; Membrane Potentials; Neurons; Peptide Fragments; Protein Kinases; Rats; Vasoactive Intestinal Peptide | 1990 |
Further characterization of the iodide inhibitory effect on the cyclic AMP system in dog thyroid slices.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine Triphosphate; Alprostadil; Animals; Calcium; Cholera Toxin; Colforsin; Cyclic AMP; Diterpenes; Dogs; Iodides; Iodine Radioisotopes; Methimazole; Prostaglandins E; Protein Biosynthesis; RNA; Thyroid Gland; Thyrotropin; Triiodothyronine | 1985 |
Role of adenosine 3',5'-cyclic monophosphate in adrenoceptor-mediated control of 3H-noradrenaline secretion in guinea-pig ileum myenteric nerve terminals.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Guinea Pigs; Ileum; In Vitro Techniques; Isoproterenol; Male; Myenteric Plexus; Nerve Endings; Nicotinic Acids; Norepinephrine; Phosphodiesterase Inhibitors; Propranolol; Receptors, Adrenergic; Yohimbine | 1985 |
Growth inhibition of transformed cells correlates with their junctional communication with normal cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Arvicolinae; Cell Communication; Cell Transformation, Neoplastic; Colforsin; Contact Inhibition; Cyclic AMP; Intercellular Junctions; Ion Channels; Mice; Rats; Tretinoin; Vitamin A; Xanthines | 1986 |
Effect of phosphodiesterase inhibitors on Sertoli cell refractoriness: reversal of the impaired androgen aromatization.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Bucladesine; Cholera Toxin; Colforsin; Cyclic AMP; Estrogens; Follicle Stimulating Hormone; Isoproterenol; Male; Phosphodiesterase Inhibitors; Rats; Receptors, Cell Surface; Receptors, FSH; Sertoli Cells | 1986 |
Ca2+-, phorbol ester-, and cAMP-stimulated enzyme secretion from permeabilized rat pancreatic acini.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Amylases; Animals; Calcium; Carbachol; Cell Membrane Permeability; Colforsin; Cyclic AMP; Cytoplasmic Granules; Digitonin; Egtazic Acid; Pancreas; Phorbols; Rats; Rats, Inbred Strains; Saponins; Spermine; Tetradecanoylphorbol Acetate; Trifluoperazine | 1986 |
Cyclic adenosine 3',5'-monophosphate mediates beta-receptor actions of noradrenaline in rat hippocampal pyramidal cells.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Adenine; Adenylyl Cyclase Inhibitors; Animals; Calcium; Colforsin; Cyclic AMP; Guanylyl Imidodiphosphate; Hippocampus; In Vitro Techniques; Isoproterenol; Neurons; Norepinephrine; Potassium; Rats | 1986 |
Stimulation of sulfated-proteoglycan synthesis by forskolin in monolayer cultures of rabbit articular chondrocytes.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Cartilage, Articular; Cells, Cultured; Chemical Phenomena; Chemistry; Chondroitin Sulfate Proteoglycans; Colforsin; Cyclic AMP; Glycosaminoglycans; Proteoglycans; Rabbits; Stimulation, Chemical | 1986 |
Age-related decrease in beta adrenergic receptor-mediated vascular smooth muscle relaxation.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetylcholine; Aging; Bucladesine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Iodocyanopindolol; Isoproterenol; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Pindolol; Receptors, Adrenergic, beta; Serotonin | 1986 |
Comparative study of the effects of cyclic nucleotide phosphodiesterase inhibitors on bone resorption and cyclic AMP formation in vitro.
Topics: 1-Methyl-3-isobutylxanthine; 2',3'-Cyclic-Nucleotide Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Bone and Bones; Bone Resorption; Calcium; Colforsin; Cyclic AMP; Dinoprostone; In Vitro Techniques; Indomethacin; Kinetics; Lysosomes; Mice; Parathyroid Hormone; Prostaglandins E; Pyrrolidinones; Rolipram; Theophylline | 1986 |
Activators of protein kinase C act at a postreceptor site to amplify cyclic AMP production in rat pinealocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenergic alpha-Agonists; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Activation; Female; Phenylephrine; Phorbol Esters; Pineal Gland; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1988 |
Reciprocal modulation of calcium current by serotonin and dopamine in the identified Aplysia neuron R15.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Aplysia; Axons; Barium; Calcium; Cells, Cultured; Colforsin; Dopamine; Egtazic Acid; Evoked Potentials; Ion Channels; Neurons; Serotonin | 1988 |
Excitation of locus coeruleus neurons by an adenosine 3',5'-cyclic monophosphate-activated inward current: extracellular and intracellular studies in rat brain slices.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Locus Coeruleus; Male; Membrane Potentials; Neurons; Rats; Reference Values; Theophylline | 1987 |
Sphingosine and psychosine, suggested inhibitors of protein kinase C, inhibit LH effects in rat luteal cells.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Brain; Bucladesine; Colforsin; Corpus Luteum; Cyclic AMP; Cytosol; Dose-Response Relationship, Drug; Female; Luteal Cells; Luteinizing Hormone; Progesterone; Protein Kinase C; Psychosine; Rats; Rats, Inbred Strains; Sphingosine | 1988 |
Inactivation of cyclic AMP-dependent taurine release from astroglia.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenylyl Cyclases; Bucladesine; Cell Line; Colforsin; Cyclic AMP; Enzyme Activation; Isoproterenol; Kinetics; Neuroglia; Receptors, Adrenergic, beta; Taurine | 1989 |
Calcitonin gene-related peptide regulates phosphorylation of the nicotinic acetylcholine receptor in rat myotubes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Calcitonin Gene-Related Peptide; Cells, Cultured; Colforsin; Cyclic AMP; Muscles; Neuromuscular Junction; Phosphorylation; Phosphoserine; Protein Kinases; Protein Processing, Post-Translational; Receptors, Nicotinic | 1989 |
Progestin-dependent effect of forskolin on human endometrial aromatase activity.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Aromatase; Cells, Cultured; Colforsin; Cyclic AMP; Endometrium; Estradiol; Female; Humans; Medroxyprogesterone; Medroxyprogesterone Acetate; Menstrual Cycle; Pregnancy; Progestins | 1987 |
Effect of forskolin and prostaglandin E1 on stimulus secretion coupling in cultured bovine adrenal chromaffin cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenal Glands; Alprostadil; Animals; Bucladesine; Calcimycin; Calcium; Cattle; Chromaffin System; Colforsin; Cyclic AMP; Drug Synergism; Nicotine; Norepinephrine; Potassium | 1988 |
Impaired mobility of human T lymphocyte surface molecules during inactive systemic lupus erythematosus. Relationship to a defective cAMP pathway.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adult; Antigens, Surface; Azides; Colforsin; Cyclic AMP; Female; Humans; Immunologic Capping; Lupus Erythematosus, Systemic; Male; Receptors, Cyclic AMP; T-Lymphocytes | 1988 |
Augmentation of postconfluence growth arrest of 10T1/2 fibroblasts by endogenous cyclic adenosine 3':5'-monophosphate.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenylyl Cyclases; Animals; Cell Division; Cell Line; Colforsin; Contact Inhibition; Cyclic AMP; Cytoplasm; In Vitro Techniques; Mice; Phosphodiesterase Inhibitors; Phosphoproteins; Time Factors | 1988 |
Adenosine receptors activate adenylate cyclase and enhance secretion from bovine adrenal chromaffin cells in the presence of forskolin.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Adrenal Gland Neoplasms; Adrenal Glands; Animals; Cattle; Chromaffin System; Colforsin; Cyclic AMP; Drug Synergism; Enzyme Activation; Kinetics; Phosphorylation; Receptors, Purinergic; Tumor Cells, Cultured | 1988 |
Control of human T-lymphocyte interleukin-2 production by a cAMP-dependent pathway.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenylyl Cyclases; Adolescent; Adult; Aged; Azides; Calcimycin; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Immunologic; Female; Humans; Immunosuppressive Agents; Interleukin-1; Interleukin-2; Lymphocyte Activation; Male; Middle Aged; Phosphorylation; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1988 |
The effect of relaxin on cyclic adenosine 3',5'-monophosphate concentrations in human endometrial glandular epithelial cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adult; Colforsin; Cyclic AMP; Endometrium; Epithelial Cells; Female; Humans; Imidazoles; In Vitro Techniques; Middle Aged; Phosphodiesterase Inhibitors; Relaxin | 1988 |
Alpha 2-adrenergic regulation of arylalkylamine N-acetyltransferase in organ-cultured chick pineal gland: characterization with agonists and modulation of experimentally stimulated enzyme activity.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetyltransferases; Adrenergic alpha-Agonists; Animals; Arylamine N-Acetyltransferase; Bucladesine; Chickens; Cholera Toxin; Circadian Rhythm; Clonidine; Colforsin; Organ Culture Techniques; Pineal Gland; Potassium Chloride; Receptors, Adrenergic, alpha | 1987 |
Requirements for and kinetics of growth arrest of neoplastic cells by confluent 10T1/2 fibroblasts induced by a specific inhibitor of cyclic adenosine 3':5'-phosphodiesterase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Cell Communication; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Colforsin; Culture Media; Diterpenes; Fibroblasts; Imidazoles; Kinetics; Mice; Nucleotides, Cyclic | 1985 |
Forskolin enhancement of acetylcholine-evoked cyclic AMP formation and catecholamine release in perfused dog adrenals.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetylcholine; Adrenal Glands; Animals; Caffeine; Calcium; Catecholamines; Colforsin; Cyclic AMP; Dogs; Female; In Vitro Techniques; Male; Potassium | 1986 |
cAMP-dependent protein kinase and lipolysis in rat adipocytes. II. Definition of steady-state relationship with lipolytic and antilipolytic modulators.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adipose Tissue; Animals; Colforsin; Cosyntropin; Deoxyadenosines; Dideoxyadenosine; Enzyme Activation; Glucagon; Glycerol; Isoproterenol; Kinetics; Lipolysis; Male; Phenylisopropyladenosine; Protein Kinases; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Modulation of potassium current kinetics in bag cell neurons of Aplysia by an activator of adenylate cyclase.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Action Potentials; Adenylyl Cyclases; Animals; Aplysia; Cells, Cultured; Colforsin; Cyclic AMP; Diterpenes; Enzyme Activation; Ion Channels; Kinetics; Neurons; Neurosecretory Systems; Potassium | 1984 |
Regulation of thromboplastin synthesis in mouse placental cells in vitro.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Depression, Chemical; Dinoprostone; Diterpenes; Epinephrine; Female; In Vitro Techniques; Mice; Placenta; Pregnancy; Prostaglandins E; Stimulation, Chemical; Thromboplastin | 1983 |
Forskolin stimulation of thyroid adenylate cyclase and cyclic 3',5'-adenosine monophosphate accumulation.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Diterpenes; Guanylyl Imidodiphosphate; Guinea Pigs; Isoproterenol; Magnesium; Manganese; Thyroid Gland; Thyrotropin; Time Factors | 1982 |
Adenosine 3':5'-cyclic monophosphate mediates a 5-hydroxytryptamine-induced response in neonatal rat motoneurones.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenylyl Cyclases; Animals; Animals, Newborn; Brain Stem; Bucladesine; Cesium; Colforsin; Cyclic AMP; Enzyme Inhibitors; Ion Channels; Isoquinolines; Membrane Potentials; Motor Neurons; Piperazines; Protein Kinase C; Rats; Serotonin; Spinal Cord | 1995 |
Analysis of the proenkephalin second messenger-inducible enhancer in rat striatal cultures.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Base Sequence; Cells, Cultured; Colforsin; Corpus Striatum; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Enhancer Elements, Genetic; Enkephalins; Fetus; Genes, fos; Molecular Sequence Data; Phosphorylation; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Second Messenger Systems; Transcription Factor AP-1 | 1995 |
Opposite effects of cyclic AMP on the expression of the genes encoding ribonucleotide reductase in Swiss 3T3 and RAT 1 cells.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Cycle; Cell Division; Cell Line; Colforsin; Cyclic AMP; DNA; Gene Expression Regulation, Enzymologic; Insulin; Mice; Rats; Ribonucleotide Reductases | 1993 |
Modulation of cyclic AMP production by strial marginal cells from gerbil in culture.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenylyl Cyclases; Alprostadil; Analysis of Variance; Animals; Cells, Cultured; Colforsin; Collagen; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Endolymph; Epinephrine; Gerbillinae; Immunohistochemistry; Isoproterenol; Male; Microscopy, Electron; Stria Vascularis; Vasopressins | 1994 |
Production of PGE2 by bovine cultured airway smooth muscle cells: regulation by cAMP.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Albuterol; Animals; Bradykinin; Bucladesine; Cattle; Cell Count; Colforsin; Culture Media; Cyclic AMP; Cycloheximide; Dinoprostone; In Vitro Techniques; Muscle, Smooth; Phosphodiesterase Inhibitors; Trachea | 1995 |
Colforsin or imidazolidione potentiates cAMP elevation caused by endothelin-1 in rat aorta.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Aorta, Thoracic; Calcium; Cats; Colforsin; Cyclic AMP; Endothelins; Muscle, Smooth, Vascular; Nifedipine; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1994 |
Heterogeneity of circulating and exudated polymorphonuclear leukocytes in superoxide-generating response to cyclic AMP and cyclic AMP-elevating agents. Investigation of the underlying mechanism.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Albuterol; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Exudates and Transudates; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peritoneum; Rabbits; Saliva; Superoxides | 1995 |
nMDA receptor activation increases cyclic AMP in area CA1 of the hippocampus via calcium/calmodulin stimulation of adenylyl cyclase.
Topics: 2-Amino-5-phosphonovalerate; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenylyl Cyclases; Animals; Ascorbic Acid; Calcium; Calmodulin; Cell Membrane; Colforsin; Cyclic AMP; Deoxyadenosines; Dopamine; Enzyme Activation; Evoked Potentials; Glycine; Hippocampus; In Vitro Techniques; Isoproterenol; Kinetics; Models, Neurological; N-Methylaspartate; Pyramidal Tracts; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Sulfonamides; Theophylline; Trifluoperazine | 1993 |
Inhibition of chemotactic peptide-induced neutrophil adhesion to vascular endothelium by cAMP modulators.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Benzoxazines; CD18 Antigens; Cell Adhesion; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Cytoplasmic Granules; Endothelium, Vascular; Humans; Infant, Newborn; Isoproterenol; Macrophage-1 Antigen; Milrinone; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxazines; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyridazines; Pyridones; Pyrrolidinones; Respiratory Burst; Rolipram; Umbilical Veins | 1995 |
Modulation of cyclic AMP metabolism by protein kinase C in PC18 cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Colforsin; Cyclic AMP; Humans; Phenylisopropyladenosine; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Modulatory effect of cyclic AMP on calcium fluxes in FRTL-5 cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine Triphosphate; Animals; Calcium; Calcium-Transporting ATPases; Cell Line; Colforsin; Cyclic AMP; Fura-2; Rats; Terpenes; Thapsigargin; Thyroid Gland | 1993 |
Cyclic adenosine monophosphate response in primary and subcultured bladder epithelial cells: inhibition by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Alkaloids; Animals; Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Dogs; Dose-Response Relationship, Drug; Epidermal Growth Factor; Epithelial Cells; Epithelium; Indomethacin; Models, Biological; Protein Kinase C; Second Messenger Systems; Signal Transduction; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Urinary Bladder | 1993 |
Congestive heart failure alters receptor-dependent cAMP-mediated relaxation of canine pulmonary arteries.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Dogs; Heart; Heart Failure; Myocardial Contraction; Phosphodiesterase Inhibitors; Pulmonary Artery; Receptors, Cell Surface; Vasodilation | 1993 |
Involvement of cyclic AMP in the effects of phosphodiesterase IV inhibitors on arachidonate release from mononuclear cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Arachidonic Acid; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Phosphoric Diester Hydrolases; Radioligand Assay | 1995 |
Effect of adenosine 3',5'-cyclic monophosphate (cAMP) on human non-tumorigenic and tumorigenic parotid acinar cells in culture.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenoma, Pleomorphic; Alprostadil; Bucladesine; Cell Differentiation; Cell Division; Cell Size; Cell Transformation, Neoplastic; Cells, Cultured; Colforsin; Cyclic AMP; Humans; Parotid Gland; Parotid Neoplasms; Phosphodiesterase Inhibitors; Receptors, Prostaglandin E; Tumor Cells, Cultured | 1996 |
Role of cyclic AMP in hydrogen peroxide-induced potentiation of sympathetic neurotransmission in the bovine iris.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Cattle; Colforsin; Cyclic AMP; Hydrogen Peroxide; Iris; Norepinephrine; Phosphodiesterase Inhibitors; Sympathetic Nervous System; Synaptic Transmission | 1997 |
Evidence that activation of protein kinase A inhibits human hair follicle growth and hair fibre production in organ culture and DNA synthesis in human and mouse hair follicle organ culture.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenylyl Cyclases; Animals; Bucladesine; Colforsin; Cyclic AMP-Dependent Protein Kinases; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Female; Hair; Hair Follicle; Humans; Mice; Organ Culture Techniques; Phosphodiesterase Inhibitors; Vibrissae | 1997 |
Beta-adrenergic regulation of renin expression in differentiated U-937 monocytic cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Bucladesine; Cell Differentiation; Cell Line; Colforsin; Enzyme Precursors; Gene Expression Regulation; Humans; Macrophages; Monocytes; Phorbol 12,13-Dibutyrate; Receptors, Adrenergic, beta; Renin; Terbutaline | 1997 |
Activation of phosphodiesterase IV during desensitization of the A2A adenosine receptor-mediated cyclic AMP response in rat pheochromocytoma (PC12) cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adrenal Gland Neoplasms; Animals; Blotting, Western; Caffeine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; Enzyme Activation; Enzyme Inhibitors; Isoquinolines; Kinetics; PC12 Cells; Phenethylamines; Pheochromocytoma; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Recombinant Proteins; Sulfonamides | 1997 |
Rolipram, a selective inhibitor of phosphodiesterase type 4, pronouncedly enhanced the forskolin-induced promotion of dopamine biosynthesis in primary cultured rat mesencephalic neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Cells, Cultured; Colforsin; Cyclic Nucleotide Phosphodiesterases, Type 1; Cyclic Nucleotide Phosphodiesterases, Type 4; Dopamine; Embryo, Mammalian; Female; Mesencephalon; Neurons; Phosphodiesterase Inhibitors; Pregnancy; Pyrrolidinones; Rats; Rats, Wistar; Rolipram; Vinca Alkaloids | 1997 |
The role of cyclic AMP as a precursor of extracellular adenosine in the rat hippocampus.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Animals; Colforsin; Cyclic AMP; Diterpenes; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Guanosine Monophosphate; Hippocampus; In Vitro Techniques; Male; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline | 1997 |
Modulation of mitochondrial Ca2+ in ECV304 endothelial cells by agents which elevate cAMP.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Bucladesine; Calcium; Cell Line; Colforsin; Cyclic AMP; Endothelium, Vascular; Humans; Mitochondria; Phosphodiesterase Inhibitors | 1997 |
Dependence of the Ca2+-inhibitable adenylyl cyclase of C6-2B glioma cells on capacitative Ca2+ entry.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Biological Transport; Brain; Calcium; Cell Membrane; Colforsin; Cyclic AMP; Egtazic Acid; Glioma; Ionomycin; Ionophores; Kinetics; Rats; Thapsigargin; Tumor Cells, Cultured | 1998 |
Synergistic inhibition of vascular smooth muscle cell migration by phosphodiesterase 3 and phosphodiesterase 4 inhibitors.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Animals; Aorta; Becaplermin; Cell Movement; Cells, Cultured; Colforsin; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Drug Synergism; Humans; Kinetics; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Quinolones; Rats; Recombinant Proteins | 1998 |
Masking of forskolin-induced long-term potentiation by adenosine accumulation in area CA1 of the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Male; Nerve Fibers; Neurons; Probenecid; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Synapses; Thionucleotides; Xanthines | 1999 |
Inhibition of tumor necrosis factor-alpha induced neutrophil apoptosis by cyclic AMP: involvement of caspase cascade.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Apoptosis; Bucladesine; Caspases; Colforsin; Cyclic AMP; Cycloheximide; Dose-Response Relationship, Drug; Drug Synergism; Humans; In Vitro Techniques; Neutrophils; Protein Kinase C; Tumor Necrosis Factor-alpha | 1999 |
Deletion of protein kinase A phosphorylation sites in the HERG potassium channel inhibits activation shift by protein kinase A.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Amino Acid Sequence; Amino Acid Substitution; Animals; Cation Transport Proteins; Cell Membrane; Colforsin; Consensus Sequence; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Female; Humans; Membrane Potentials; Models, Molecular; Mutagenesis, Site-Directed; Oocytes; Phosphorylation; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Folding; Recombinant Proteins; Sequence Deletion; Trans-Activators; Transcriptional Regulator ERG; Xenopus laevis | 1999 |
Participation of cAMP in the facilitatory action of beta,gamma-methylene ATP on the noradrenaline release from rabbit ear artery.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Arteries; Cholera Toxin; Colforsin; Cyclic AMP; Drug Synergism; Ear; Electric Stimulation; Enzyme Activation; Female; Male; Norepinephrine; Phosphodiesterase Inhibitors; Rabbits | 1999 |
Induction of arginase II in human Caco-2 tumor cells by cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Arginase; Caco-2 Cells; Colforsin; Cyclic AMP; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Isoquinolines; Kinetics; Okadaic Acid; Protein Biosynthesis; RNA, Messenger; Sulfonamides; Transcription, Genetic | 2000 |
Cyclic AMP regulates cytokine stimulation of endothelin-1 release in human vascular smooth muscle cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Cells, Cultured; Colforsin; Cyclic AMP; Cytokines; Endothelin-1; Endothelins; Epoprostenol; Humans; Interferon-gamma; Muscle, Smooth, Vascular; Protein Precursors; RNA, Messenger; Tumor Necrosis Factor-alpha | 2000 |
Modulation of excitability in Aplysia tail sensory neurons by tyrosine kinases.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Action Potentials; Animals; Aplysia; Benzoquinones; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Genistein; Lactams, Macrocyclic; Neuronal Plasticity; Neurons, Afferent; Organometallic Compounds; Phenanthrolines; Phenols; Phosphodiesterase Inhibitors; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quinones; Rifabutin; Serotonin; src-Family Kinases; Tail | 2001 |
Pharmacological characterization of adenosine receptors in PGT-beta mouse pineal gland tumour cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Calcium; Colforsin; Cyclic AMP; Dihydropyridines; Dose-Response Relationship, Drug; Enzyme Activation; Estrenes; Gene Expression Regulation, Neoplastic; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Isoproterenol; Mice; Mice, Inbred CBA; Pertussis Toxin; Phospholipases; Pinealoma; Pyrrolidinones; Receptor, Adenosine A2B; Receptor, Adenosine A3; Receptors, Purinergic P1; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Virulence Factors, Bordetella | 2001 |
Altered phosphodiesterase 3-mediated cAMP hydrolysis contributes to a hypermotile phenotype in obese JCR:LA-cp rat aortic vascular smooth muscle cells: implications for diabetes-associated cardiovascular disease.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Aorta; Cell Membrane; Cell Movement; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Cytosol; Diabetes Mellitus, Type 2; Hydrolysis; Muscle, Smooth, Vascular; Obesity; Phenotype; Phosphodiesterase Inhibitors; Quinolones; Rats; Rats, Mutant Strains | 2002 |
The human D2 dopamine receptor synergizes with the A2A adenosine receptor to stimulate adenylyl cyclase in PC12 cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenylyl Cyclases; Animals; Benzamides; Binding, Competitive; Cell Cycle; Cell Membrane; Cofilin 1; Colforsin; Cyclic AMP; Cytoskeletal Proteins; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Enzyme Activation; Gene Expression; Glutamic Acid; Humans; Membrane Potentials; Patch-Clamp Techniques; PC12 Cells; Pertussis Toxin; Phenethylamines; Phosphodiesterase Inhibitors; Phosphoproteins; Propionates; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrrolidines; Quinpirole; Radioligand Assay; Rats; Receptors, Dopamine D2; Receptors, Purinergic P1; Thionucleotides; Transfection; Triazines; Triazoles; Xenopus Proteins | 2003 |
Group II metabotropic glutamate receptor modulation of excitatory transmission in rat subthalamic nucleus.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenylyl Cyclase Inhibitors; Amino Acids; Amino Acids, Dicarboxylic; Animals; Colforsin; Cyclopropanes; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Glycine; Imines; In Vitro Techniques; Isoquinolines; Male; Picrotoxin; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Subthalamic Nucleus; Sulfonamides; Synaptic Transmission; Tetradecanoylphorbol Acetate; Xanthenes | 2003 |
Phosphodiesterase-linked inhibition of nonmicturition activity in the isolated bladder.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Colforsin; Cyclic AMP; Female; Guinea Pigs; Muscle Contraction; Phosphodiesterase Inhibitors; Pressure; Urinary Bladder; Urination | 2004 |
Autoinhibition of transmitter release from PC12 cells and sympathetic neurons through a P2Y receptor-mediated inhibition of voltage-gated Ca2+ channels.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Monophosphate; Animals; Animals, Newborn; Cadmium; Calcium Channels; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Ganglia, Sympathetic; Membrane Potentials; Membrane Proteins; Neural Inhibition; Neurons; Norepinephrine; Patch-Clamp Techniques; PC12 Cells; Pertussis Toxin; Phenethylamines; Potassium; Purine Nucleotides; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Suramin; Thionucleosides; Tritium | 2004 |
Ca(2+)-dependent K(+) currents and spike-frequency adaptation in medial entorhinal cortex layer II stellate cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Action Potentials; Adaptation, Physiological; Animals; Animals, Newborn; Apamin; Cadmium Chloride; Colforsin; Dose-Response Relationship, Radiation; Electric Stimulation; Entorhinal Cortex; In Vitro Techniques; Male; Neurons; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Potassium Channels, Calcium-Activated; Rats | 2007 |
Numerous distinct PKA-, or EPAC-based, signalling complexes allow selective phosphodiesterase 3 and phosphodiesterase 4 coordination of cell adhesion.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenylyl Cyclases; Cell Adhesion; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Enzyme Activators; Guanine Nucleotide Exchange Factors; Humans; Multiprotein Complexes; Peptide Fragments; Phosphodiesterase 3 Inhibitors; Phosphodiesterase Inhibitors; Protein Structure, Tertiary; Quinolones; Signal Transduction; Transfection | 2007 |
Impact of anti-inflammatory agents on the gene expression profile of stimulated human neutrophils: unraveling endogenous resolution pathways.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Colforsin; Dinoprostone; Gene Expression; Gene Expression Profiling; Humans; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligonucleotide Array Sequence Analysis; Oxytocics; Phenethylamines; Phosphodiesterase Inhibitors; Signal Transduction | 2009 |
Regulation of renovascular adenosine 3',5'-cyclic monophosphate in spontaneously hypertensive rats.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Analysis of Variance; Animals; Blood Pressure; Blood Pressure Determination; Colforsin; Cyclic AMP; Disease Models, Animal; Hypertension, Renovascular; Isoproterenol; Kidney; Male; Probability; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; Renal Circulation; Sensitivity and Specificity; Xanthines | 2009 |
Acute stress impairs hippocampal mossy fiber-CA3 long-term potentiation by enhancing cAMP-specific phosphodiesterase 4 activity.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenalectomy; Animals; Anti-Inflammatory Agents; Biophysical Phenomena; Colforsin; Corticosterone; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Mineralocorticoid Receptor Antagonists; Mossy Fibers, Hippocampal; Phosphodiesterase Inhibitors; Spironolactone; Stress, Psychological; Synaptosomes; Xanthines | 2010 |
Exposure of human seminal vesicle tissue to phosphodiesterase (PDE) inhibitors antagonizes the contraction induced by norepinephrine and increases production of cyclic nucleotides.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Aged; Colforsin; Cyclic AMP; Cyclic GMP; Drug Evaluation, Preclinical; Ejaculation; Humans; In Vitro Techniques; Male; Milrinone; Muscle Relaxation; Nitroprusside; Norepinephrine; Phosphodiesterase Inhibitors; Piperazines; Purines; Receptors, Adrenergic, alpha; Rolipram; Seminal Vesicles; Sildenafil Citrate; Sulfones | 2010 |
Evaluating the significance of cyclic adenosine monophosphate-mediated signaling in human prostate: a functional and biochemical study.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Aged; Benzamides; Colforsin; Cyclic AMP; Humans; In Vitro Techniques; Inhibitory Concentration 50; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Papaverine; Phosphodiesterase 4 Inhibitors; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Prostate; Purines; Pyridines; Rolipram; Signal Transduction; Sildenafil Citrate; Sulfones | 2012 |