Compounds > 4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone
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4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone and carbostyril

4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone has been researched along with carbostyril in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19905 (31.25)18.7374
1990's5 (31.25)18.2507
2000's6 (37.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Endoh, M; Katano, Y1
Bode, DC; Brunton, LL; Kanter, JR1
Elks, ML; Manganiello, VC2
Degerman, E; Elks, M; Manganiello, V1
Hidaka, H; Manganiello, VC; Osborne, JC; Vaughan, M; Yamamoto, S; Yamamoto, T1
Hidaka, H; Lieberman, F; Manganiello, VC; Osborne, JC; Vaughan, M; Yamamoto, T1
Imai, A; Nashida, T; Shimomura, H1
Downing, GJ; Poisner, AM; Poisner, R1
Maurice, DH; Palmer, D; Tsoi, K1
Absher, PM; Dunkerley, HA; Jimmo, SL; Maurice, DH; Netherton, SJ; Palmer, D; Raymond, DR; Russell, JC; Sage, EH; Tilley, DG; Vernon, RB1
Abzhalelov, BB; Bronnikov, GE; Dolgacheva, LP; Zhang, SJ; Zinchenko, VP1
Degerman, E; Manganiello, V; Oknianska, A; Zmuda-Trzebiatowska, E1
Carter, RL; Maurice, DH; Raymond, DR; Wilson, LS1
Abi-Gerges, A; Conti, M; Fischmeister, R; Lechêne, P; Leroy, J; Mazet, JL; Nikolaev, VO; Richter, W; Vandecasteele, G1
Abi-Gerges, A; Conti, M; Fischmeister, R; Heymes, C; Lefebvre, F; Lugnier, C; Mateo, P; Richter, W; Samuel, JL; Vandecasteele, G; Varin, A1

Other Studies

16 other study(ies) available for 4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone and carbostyril

ArticleYear
Effects of a cardiotonic quinolinone derivative Y-20487 on the isoproterenol-induced positive inotropic action and cyclic AMP accumulation in rat ventricular myocardium: comparison with rolipram, Ro 20-1724, milrinone, and isobutylmethylxanthine.
    Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:5

    Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Cardiotonic Agents; Cyclic AMP; Dose-Response Relationship, Drug; Heart Rate; Isoproterenol; Male; Milrinone; Myocardial Contraction; Myocardium; Papillary Muscles; Phosphodiesterase Inhibitors; Pyridones; Pyrrolidinones; Quinolones; Rats; Rats, Wistar; Rolipram; Stimulation, Chemical; Thiadiazines

1992
Cellular distribution of phosphodiesterase isoforms in rat cardiac tissue.
    Circulation research, 1991, Volume: 68, Issue:4

    Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cyclic GMP; Heart Ventricles; Isoenzymes; Kinetics; Male; Milrinone; Myocardium; Phosphodiesterase Inhibitors; Pyridones; Pyrrolidinones; Quinolones; Rats; Rats, Inbred Strains; Rolipram; Substrate Specificity

1991
A role for soluble cAMP phosphodiesterases in differentiation of 3T3-L1 adipocytes.
    Journal of cellular physiology, 1985, Volume: 124, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Adipose Tissue; Animals; Azo Compounds; Cell Differentiation; Cell Line; Dexamethasone; Glycerolphosphate Dehydrogenase; Insulin; Lipid Metabolism; Mice; Phenylisopropyladenosine; Quinolines; Quinolones; Solubility; Theophylline; Time Factors

1985
Selective inhibitors of specific phosphodiesterases in intact adipocytes.
    Methods in enzymology, 1988, Volume: 159

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adipose Tissue; Animals; Cattle; Cells, Cultured; Cyclic GMP; Dexamethasone; Insulin; Kinetics; Liver; Mice; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Quinolines; Quinolones; Rats; Structure-Activity Relationship

1988
Complex effects of inhibitors on cyclic GMP-stimulated cyclic nucleotide phosphodiesterase.
    The Journal of biological chemistry, 1983, Dec-10, Volume: 258, Issue:23

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Cattle; Dipyridamole; Hydrolysis; Kinetics; Liver; Papaverine; Quinolines; Quinolones; Theophylline

1983
Selective effects of phosphodiesterase inhibitors on different phosphodiesterases, adenosine 3',5'-monophosphate metabolism, and lipolysis in 3T3-L1 adipocytes.
    Endocrinology, 1984, Volume: 115, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adipose Tissue; Animals; Cell Line; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Kinetics; Lipolysis; Mice; Phosphodiesterase Inhibitors; Quinolines; Quinolones

1984
Selective inhibition of two soluble adenosine cyclic 3',5'-phosphate phosphodiesterases partially purified from calf liver.
    Biochemistry, 1984, Feb-14, Volume: 23, Issue:4

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Cattle; Cyclic GMP; Kinetics; Liver; Quinolines; Quinolones; Solubility

1984
Characterization of cyclic AMP phosphodiesterase isozymes in rat parotid gland.
    Archives of oral biology, 1995, Volume: 40, Issue:2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Calcium; Calmodulin; Chromatography, Agarose; Cyclic GMP; Enzyme Activation; Isoenzymes; Kinetics; Male; Milrinone; Molecular Weight; Parotid Gland; Phosphodiesterase Inhibitors; Pyridones; Pyrrolidinones; Quinolones; Rats; Rats, Wistar; Rolipram

1995
Phosphodiesterase inhibitors have differential effects on placental versus decidual prorenin release.
    Proceedings of the Western Pharmacology Society, 1994, Volume: 37

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Chorion; Culture Media; Decidua; Enzyme Precursors; Extraembryonic Membranes; Female; Humans; In Vitro Techniques; Phosphodiesterase Inhibitors; Placenta; Platelet Aggregation Inhibitors; Pregnancy; Quinolones; Renin

1994
Synergistic inhibition of vascular smooth muscle cell migration by phosphodiesterase 3 and phosphodiesterase 4 inhibitors.
    Circulation research, 1998, May-04, Volume: 82, Issue:8

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenine; Animals; Aorta; Becaplermin; Cell Movement; Cells, Cultured; Colforsin; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Drug Synergism; Humans; Kinetics; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Quinolones; Rats; Recombinant Proteins

1998
Altered phosphodiesterase 3-mediated cAMP hydrolysis contributes to a hypermotile phenotype in obese JCR:LA-cp rat aortic vascular smooth muscle cells: implications for diabetes-associated cardiovascular disease.
    Diabetes, 2002, Volume: 51, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Aorta; Cell Membrane; Cell Movement; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Cytosol; Diabetes Mellitus, Type 2; Hydrolysis; Muscle, Smooth, Vascular; Obesity; Phenotype; Phosphodiesterase Inhibitors; Quinolones; Rats; Rats, Mutant Strains

2002
Norepinephrine induces slow calcium signalling in murine brown preadipocytes through the beta-adrenoceptor/cAMP/protein kinase A pathway.
    Cellular signalling, 2003, Volume: 15, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adipocytes; Adipose Tissue, Brown; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Calcium Signaling; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Isoproterenol; Isoquinolines; Male; Mice; Mice, Inbred Strains; Norepinephrine; Phosphodiesterase Inhibitors; Quinolones; Receptors, Adrenergic, beta; Sulfonamides; Thapsigargin

2003
Role of PDE3B in insulin-induced glucose uptake, GLUT-4 translocation and lipogenesis in primary rat adipocytes.
    Cellular signalling, 2006, Volume: 18, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adipocytes; Animals; Blotting, Western; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Dioxoles; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Glucose; Glucose Transporter Type 4; Guanine Nucleotide Exchange Factors; Insulin; Isoquinolines; Lipogenesis; Male; Quinolones; Rats; Rats, Sprague-Dawley; Signal Transduction; Sulfonamides

2006
Numerous distinct PKA-, or EPAC-based, signalling complexes allow selective phosphodiesterase 3 and phosphodiesterase 4 coordination of cell adhesion.
    Cellular signalling, 2007, Volume: 19, Issue:12

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenylyl Cyclases; Cell Adhesion; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Enzyme Activators; Guanine Nucleotide Exchange Factors; Humans; Multiprotein Complexes; Peptide Fragments; Phosphodiesterase 3 Inhibitors; Phosphodiesterase Inhibitors; Protein Structure, Tertiary; Quinolones; Signal Transduction; Transfection

2007
Spatiotemporal dynamics of beta-adrenergic cAMP signals and L-type Ca2+ channel regulation in adult rat ventricular myocytes: role of phosphodiesterases.
    Circulation research, 2008, May-09, Volume: 102, Issue:9

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenergic beta-Agonists; Animals; Biosensing Techniques; Calcium Channels, L-Type; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclic Nucleotide-Gated Cation Channels; Cytosol; Dose-Response Relationship, Drug; Enzyme Activation; Fluorescence Resonance Energy Transfer; Guanine Nucleotide Exchange Factors; Heart Ventricles; Isoproterenol; Kinetics; Male; Membrane Potentials; Microscopy, Fluorescence; Myocardial Contraction; Myocytes, Cardiac; Phosphodiesterase 3 Inhibitors; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Phosphorylation; Quinolones; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Sarcolemma; Signal Transduction; Transfection

2008
Decreased expression and activity of cAMP phosphodiesterases in cardiac hypertrophy and its impact on beta-adrenergic cAMP signals.
    Circulation research, 2009, Oct-09, Volume: 105, Issue:8

    Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Aortic Valve Stenosis; Cardiomegaly; Cells, Cultured; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Male; Myocardial Contraction; Myocytes, Cardiac; Organ Size; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Quinolones; Rats; Rats, Wistar; Second Messenger Systems

2009