4-(2-chlorophenyl)-2-(2-(4-isobutylphenyl)ethyl)-6,9-dimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine has been researched along with pyrilamine in 2 studies
| Studies (4-(2-chlorophenyl)-2-(2-(4-isobutylphenyl)ethyl)-6,9-dimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine) | Trials (4-(2-chlorophenyl)-2-(2-(4-isobutylphenyl)ethyl)-6,9-dimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine) | Recent Studies (post-2010) (4-(2-chlorophenyl)-2-(2-(4-isobutylphenyl)ethyl)-6,9-dimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine) | Studies (pyrilamine) | Trials (pyrilamine) | Recent Studies (post-2010) (pyrilamine) |
|---|---|---|---|---|---|
| 51 | 1 | 8 | 1,860 | 26 | 116 |
| Protein | Taxonomy | 4-(2-chlorophenyl)-2-(2-(4-isobutylphenyl)ethyl)-6,9-dimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine (IC50) | pyrilamine (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 1.13 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 2.976 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.3 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.997 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 1.13 | |
| Histamine H1 receptor | Cavia porcellus (domestic guinea pig) | 0.0015 | |
| Histamine H1 receptor | Rattus norvegicus (Norway rat) | 0.0126 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.047 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.0166 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 2.788 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.879 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 1.1 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 1.558 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Harada, K; Katayama, K; Katayama, S; Muramoto, K; Sakuma, Y; Tsunoda, H | 1 |
| Iwahisa, Y; Kagoshima, M; Kawakami, Y; Matsuura, M; Terasawa, M; Tomomatsu, N; Yamaguchi, S | 1 |
2 other study(ies) available for 4-(2-chlorophenyl)-2-(2-(4-isobutylphenyl)ethyl)-6,9-dimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine and pyrilamine
| Article | Year |
|---|---|
Inhibitory effects of a novel PAF antagonist E6123 on anaphylactic responses in passively and actively sensitized guinea pigs and passively sensitized mice.
Topics: Administration, Inhalation; Anaphylaxis; Animals; Antigens; Asthma; Azepines; Guinea Pigs; Male; Mice; Mice, Inbred ICR; Ovalbumin; Platelet Activating Factor; Propranolol; Pyrilamine; Triazoles | 1991 |
Suppressive effects of Y-24180, a receptor antagonist to platelet activating factor (PAF), on antigen-induced asthmatic responses in guinea pigs.
Topics: Administration, Oral; Aerosols; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Asthma; Azepines; Benzoquinones; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchodilator Agents; Chromones; Enzyme Inhibitors; Guinea Pigs; Heptanoic Acids; Histamine Antagonists; Leukotriene Antagonists; Male; Methacrylates; Ovalbumin; Platelet Membrane Glycoproteins; Pyrilamine; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serine Proteinase Inhibitors; Signal Transduction; Theophylline; Thromboxane-A Synthase; Triazoles | 1997 |