4-(2-chlorophenyl)-2-(2-(4-isobutylphenyl)ethyl)-6,9-dimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine has been researched along with propranolol in 2 studies
| Studies (4-(2-chlorophenyl)-2-(2-(4-isobutylphenyl)ethyl)-6,9-dimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine) | Trials (4-(2-chlorophenyl)-2-(2-(4-isobutylphenyl)ethyl)-6,9-dimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine) | Recent Studies (post-2010) (4-(2-chlorophenyl)-2-(2-(4-isobutylphenyl)ethyl)-6,9-dimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine) | Studies (propranolol) | Trials (propranolol) | Recent Studies (post-2010) (propranolol) |
|---|---|---|---|---|---|
| 51 | 1 | 8 | 33,310 | 3,406 | 3,218 |
| Protein | Taxonomy | 4-(2-chlorophenyl)-2-(2-(4-isobutylphenyl)ethyl)-6,9-dimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine (IC50) | propranolol (IC50) |
|---|---|---|---|
| Beta-1 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.0347 | |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | 0.0288 | |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 2.294 | |
| Cytochrome P450 1A2 | Homo sapiens (human) | 4 | |
| Beta-2 adrenergic receptor | Homo sapiens (human) | 0.0114 | |
| Beta-1 adrenergic receptor | Homo sapiens (human) | 0.0575 | |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 3.9811 | |
| Beta-2 adrenergic receptor | Rattus norvegicus (Norway rat) | 0.012 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 2.9706 | |
| Beta-3 adrenergic receptor | Homo sapiens (human) | 0.0493 | |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | 0.0288 | |
| Beta-1 adrenergic receptor | Rattus norvegicus (Norway rat) | 0.012 | |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | 0.0288 | |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | 0.0288 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0827 | |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | 0.0288 | |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | 0.0288 | |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | 0.0288 | |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | 0.0288 | |
| Beta-3 adrenergic receptor | Rattus norvegicus (Norway rat) | 0.012 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 1.466 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 2.294 | |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | 0.0288 | |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | 0.0288 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.243 | |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | 0.0288 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.38 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.342 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 3.065 | |
| Beta-2 adrenergic receptor | Canis lupus familiaris (dog) | 0.017 | |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 0.0288 | |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | 0.0288 | |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | 0.0288 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 2.828 | |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | 2.1 | |
| Sodium/bile acid cotransporter | Homo sapiens (human) | 5.5 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.0288 | |
| GABA theta subunit | Rattus norvegicus (Norway rat) | 0.0288 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 2.87 | |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | 0.0288 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Harada, K; Katayama, K; Katayama, S; Muramoto, K; Sakuma, Y; Tsunoda, H | 1 |
| Fujimura, M; Matsuda, T; Myou, S; Songür, N; Tsujiura, M | 1 |
2 other study(ies) available for 4-(2-chlorophenyl)-2-(2-(4-isobutylphenyl)ethyl)-6,9-dimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine and propranolol
| Article | Year |
|---|---|
Inhibitory effects of a novel PAF antagonist E6123 on anaphylactic responses in passively and actively sensitized guinea pigs and passively sensitized mice.
Topics: Administration, Inhalation; Anaphylaxis; Animals; Antigens; Asthma; Azepines; Guinea Pigs; Male; Mice; Mice, Inbred ICR; Ovalbumin; Platelet Activating Factor; Propranolol; Pyrilamine; Triazoles | 1991 |
Involvement of PAF in postallergic propranolol-induced bronchoconstriction in guinea-pigs.
Topics: Administration, Inhalation; Adrenergic beta-Antagonists; Anesthesia, General; Animals; Antigens; Asthma; Azepines; Bronchoconstriction; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Hypersensitivity; Immunization; Inflammation Mediators; Injections, Intravenous; Male; Platelet Activating Factor; Propranolol; Respiration, Artificial; Time Factors; Triazoles | 1996 |