Page last updated: 2024-09-03

4-(2-chlorophenyl)-2-(2-(4-isobutylphenyl)ethyl)-6,9-dimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine and ketotifen

4-(2-chlorophenyl)-2-(2-(4-isobutylphenyl)ethyl)-6,9-dimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine has been researched along with ketotifen in 1 studies

Compound Research Comparison

Studies
(4-(2-chlorophenyl)-2-(2-(4-isobutylphenyl)ethyl)-6,9-dimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine)
Trials
(4-(2-chlorophenyl)-2-(2-(4-isobutylphenyl)ethyl)-6,9-dimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine)
Recent Studies (post-2010)
(4-(2-chlorophenyl)-2-(2-(4-isobutylphenyl)ethyl)-6,9-dimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine)
Studies
(ketotifen)
Trials
(ketotifen)
Recent Studies (post-2010) (ketotifen)
51181,212275151

Protein Interaction Comparison

ProteinTaxonomy4-(2-chlorophenyl)-2-(2-(4-isobutylphenyl)ethyl)-6,9-dimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine (IC50)ketotifen (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.16
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.838
Muscarinic acetylcholine receptor M4Homo sapiens (human)1.009
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.374
Alpha-2A adrenergic receptorHomo sapiens (human)2.187
Muscarinic acetylcholine receptor M1Homo sapiens (human)1.112
Alpha-2B adrenergic receptorHomo sapiens (human)0.71
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)2.537
Muscarinic acetylcholine receptor M3Homo sapiens (human)2.209
D(1A) dopamine receptorHomo sapiens (human)0.872
Histamine H2 receptorHomo sapiens (human)4.129
Alpha-1D adrenergic receptorHomo sapiens (human)3.727
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.031
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.16
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)2.537
Histamine H1 receptorHomo sapiens (human)0.0011
D(3) dopamine receptorHomo sapiens (human)1.963
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.046
5-hydroxytryptamine receptor 6Homo sapiens (human)1.141

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Komatsu, H; Tomomatsu, N; Yamaguchi, S1

Other Studies

1 other study(ies) available for 4-(2-chlorophenyl)-2-(2-(4-isobutylphenyl)ethyl)-6,9-dimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine and ketotifen

ArticleYear
Effect of Y-24180, a receptor antagonist to platelet-activating factor (PAF), on allergic cutaneous reactions in actively sensitized mice.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2000, Volume: 49, Issue:11

    Topics: Administration, Oral; Administration, Topical; Allergens; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Arylsulfonates; Azepines; Dermatitis, Allergic Contact; Ear; Eosinophils; Histamine H1 Antagonists; Hydrocortisone; Immunoglobulin E; Immunoglobulin G; Ketotifen; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Ovalbumin; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sulfonium Compounds; Time Factors; Triazoles

2000