4-(2-amino-6-chloro-9h-purin-9-yl)-1,3-dioxolane-2-methanol has been researched along with glutamic acid in 7 studies
| Studies (4-(2-amino-6-chloro-9h-purin-9-yl)-1,3-dioxolane-2-methanol) | Trials (4-(2-amino-6-chloro-9h-purin-9-yl)-1,3-dioxolane-2-methanol) | Recent Studies (post-2010) (4-(2-amino-6-chloro-9h-purin-9-yl)-1,3-dioxolane-2-methanol) | Studies (glutamic acid) | Trials (glutamic acid) | Recent Studies (post-2010) (glutamic acid) |
|---|---|---|---|---|---|
| 27 | 0 | 5 | 41,757 | 452 | 12,876 |
| Protein | Taxonomy | 4-(2-amino-6-chloro-9h-purin-9-yl)-1,3-dioxolane-2-methanol (IC50) | glutamic acid (IC50) |
|---|---|---|---|
| Chain A, GLUTAMATE RECEPTOR SUBUNIT 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Chain A, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Chain B, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Metabotropic glutamate receptor 8 | Homo sapiens (human) | 0.0057 | |
| Glutamate receptor ionotropic, NMDA 2D | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 3B | Homo sapiens (human) | 0.07 | |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor 1 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor 2 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor 3 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | 0.38 | |
| Excitatory amino acid transporter 1 | Homo sapiens (human) | 207 | |
| Glutamate receptor 4 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2C | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 3A | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 0.1533 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Clusmann, H; Dietrich, D; Friedl, M; Kral, T; Schramm, J | 1 |
| Shahraki, A; Stone, TW | 1 |
| Ishige, K; Ito, M; Ito, Y; Saito, H; Takagi, N | 1 |
| Albers, HE; Haak, LL; Mintz, EM | 1 |
| Dolińska, M; Grajkowska, E; Klauzińska, M; Luchenko, V; Pshenichkin, S; Wroblewski, JT | 1 |
| Barger, SW; Li, GG; McMullan, SM; Phanavanh, B | 1 |
| Enger, R; Helm, PJ; Hvalby, Ø; Jensen, V; Looger, LL; Nagelhus, EA; Sprengel, R; Szokol, K; Tang, W; Trivedi, CA | 1 |
7 other study(ies) available for 4-(2-amino-6-chloro-9h-purin-9-yl)-1,3-dioxolane-2-methanol and glutamic acid
| Article | Year |
|---|---|
Presynaptic group II metabotropic glutamate receptors reduce stimulated and spontaneous transmitter release in human dentate gyrus.
Topics: Action Potentials; Antiviral Agents; Dentate Gyrus; Dioxolanes; Excitatory Postsynaptic Potentials; Glutamic Acid; Humans; Neurotransmitter Agents; Purines; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Stimulation, Chemical | 2002 |
Interactions between adenosine and metabotropic glutamate receptors in the rat hippocampal slice.
Topics: Adenosine; Animals; Baclofen; Dioxolanes; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Male; Methoxyhydroxyphenylglycol; Protein Kinase C; Purines; Rats; Rats, Wistar; Receptors, GABA-B; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Time Factors | 2003 |
Neurotoxicity induced by amyloid beta-peptide and ibotenic acid in organotypic hippocampal cultures: protection by S-allyl-L-cysteine, a garlic compound.
Topics: Amino Acid Chloromethyl Ketones; Amyloid beta-Peptides; Animals; Cell Death; Cysteine; Dioxolanes; Drug Interactions; Excitatory Amino Acid Agonists; Garlic; Glutamic Acid; Hippocampus; Ibotenic Acid; Neurons; Neuroprotective Agents; Organ Culture Techniques; Purines; Rats; Rats, Wistar | 2003 |
Modulation of photic response by the metabotropic glutamate receptor agonist t-ACPD.
Topics: Animals; Circadian Rhythm; Cricetinae; Dioxolanes; Excitatory Amino Acid Agonists; Glutamic Acid; Light; Light Signal Transduction; Male; Mesocricetus; Neural Pathways; Purines; Receptors, Metabotropic Glutamate; Suprachiasmatic Nucleus | 2006 |
Dual neurotoxic and neuroprotective role of metabotropic glutamate receptor 1 in conditions of trophic deprivation - possible role as a dependence receptor.
Topics: Animals; Cell Survival; Cells, Cultured; Cerebellum; Cerebral Cortex; Chromones; Dioxolanes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gene Expression; Glutamic Acid; Green Fluorescent Proteins; Intercellular Signaling Peptides and Proteins; Mice; Neurons; Potassium Chloride; Purines; Pyridines; Rats; Receptors, Metabotropic Glutamate; RNA, Small Interfering; Time Factors; Transfection | 2008 |
Metabotropic glutamate receptors inhibit microglial glutamate release.
Topics: 1-Methyl-3-isobutylxanthine; Analysis of Variance; Animals; Animals, Newborn; Brain; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dioxolanes; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agents; Glutamic Acid; Lipopolysaccharides; Neuroglia; Nitrites; Purines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; RNA, Messenger | 2012 |
Stimulation-evoked Ca2+ signals in astrocytic processes at hippocampal CA3-CA1 synapses of adult mice are modulated by glutamate and ATP.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Calcium; Calcium Signaling; Calmodulin; Dioxolanes; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glial Fibrillary Acidic Protein; Glutamic Acid; Glycine; Hippocampus; Humans; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phenylacetates; Purines; Synapses; Synapsins; Time Factors | 2015 |